A5013353192- Endodontics and Root Canal Treatments
- Dental Radiography and Imaging
- Long-Term Effects of COVID-19
- Global Maternal and Child Health
- COVID-19 Clinical Research Studies
- Liver physiology and pathology
- Mesenchymal stem cell research
- SARS-CoV-2 and COVID-19 Research
- Dental Trauma and Treatments
- Drilling and Well Engineering
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bone health and osteoporosis research
- Respiratory Support and Mechanisms
- Mathematical Biology Tumor Growth
- Molecular Communication and Nanonetworks
- Immune cells in cancer
- Gene Regulatory Network Analysis
- Alkaline Phosphatase Research Studies
- Fluid dynamics and aerodynamics studies
- Aortic Thrombus and Embolism
- Sports and Physical Education Research
- Microfluidic and Bio-sensing Technologies
- Liver Disease Diagnosis and Treatment
- Cardiovascular Issues in Pregnancy
- Cervical Cancer and HPV Research
University at Buffalo, State University of New York
2020-2025
Bangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders
2020-2024
Oklahoma State University
2020-2022
Dhaka Medical College and Hospital
2020
Mymensingh Medical College Hospital
2019
Missouri University of Science and Technology
2017-2019
Bangabandhu Sheikh Mujib Medical University
2013-2014
Abstract The 2019 novel coronavirus, SARS-CoV-2, is a pathogen of critical significance to international public health. Knowledge the interplay between molecular-scale virus-receptor interactions, single-cell viral replication, intracellular-scale transport, and emergent tissue-scale propagation limited. Moreover, little known about immune system-virus-tissue interactions how these can result in low-level (asymptomatic) infections some cases acute respiratory distress syndrome (ARDS) others,...
Particle size is a key parameter for drug-delivery nanoparticle design. It believed that the of may have important effects on its ability to overcome transport barriers in biological tissues. Nonetheless, such remain poorly understood. Using multiscale model, this work investigates particle tissue distribution and penetration efficacy nanoparticles. We developed spatiotemporal model The implements time-adaptive Brownian Dynamics algorithm links microscale particle-cell interactions adhesion...
The severity of the COVID-19 pandemic has created an emerging need to investigate long-term effects infection on patients. Many individuals are at risk suffering pulmonary fibrosis due pathogenesis lung injury and impairment in healing mechanism. Fibroblasts central mediators extracellular matrix (ECM) deposition during tissue regeneration, regulated by anti-inflammatory cytokines including transforming growth factor beta (TGF-β). TGF-β-dependent accumulation fibroblasts damaged site excess...
Butyrate, a short-chain fatty acid produced by the gut microbiota, has pivotal roles in regulation of immune system. Recent studies have revealed that butyrate increases differentiation peripheral regulatory T cells gut–bone axis and promotes osteoblasts' bone forming activity. However, mechanism therapeutic benefit remodeling remains incompletely understood. Here, we develop multicompartment mathematical model to quantitatively predict contribution on expansion gut, blood, compartments. We...
Bone health is determined by factors including bone metabolism or remodeling. Wnt-10b alters osteoblastogenesis through pre-osteoblast proliferation and differentiation osteoblast apoptosis rate, which collectively lead to the increase of density. To model this, we adapted a previously published The resulting for compartment includes differential equations active osteoclasts, pre-osteoblasts, osteoblasts, osteocytes, amount present at remodeling site. Our alterations original consist...
Abstract The severity of the COVID-19 pandemic has created an emerging need to investigate long-term effects infection on patients. Many individuals are at risk suffering pulmonary fibrosis due pathogenesis lung injury and impairment in healing mechanism. Fibroblasts central mediators extracellular matrix (ECM) deposition during tissue regeneration, regulated by anti-inflammatory cytokines including transforming growth factor beta (TGF-β). TGF-β-dependent accumulation fibroblasts damaged...
This case report represents assessment and management of a maxillary left first molar tooth containing five root canals by endodontic treatment. In this Mesiobuccal 2 (MB2), Mesiopalatal (MP) Distobuccal (DB) were missed as well very poor obturation at palatal mesiobuccal1(MB1) canal during previous treatment history. Three mesiobuccal (MB1, MB2, MP), DB identified retreatment was done followed final restoration. provides an evidence variations in the tooth. Complete clinical radiographic...
Reattachment of a fractured fragment to the remaining tooth is challenging but one best treatment protocol in regards aesthetics, function as well patients acceptance. This case report presents 20 years old male with an oblique complicated crown fracture maxillary left central incisor tooth. The procedure used repair regarding this included flap surgery endodontic treatment. root canal was filled sealer and gutta-percha. After obturation, fragments were reattached duel cure composite resin...
Background: The presence of a single root canal in mandibular first premolar cannot be assumed always. variability morpholohy includes the number & shape as well pathways canals. Methods: In this study, 100 teeth were evaluated by clearing technique. Collected cleaned and merged with 5.25% NaOCl for 48 hours. Then decalcified 5% nitric acid 72 hours followed dehydrated sequentially 80-100% alcohol. After dehydration, Indian Ink was injected into through previously prepared access cavity....
A BSTRACT Background: There is continuing debate regarding universal screening, the use of a thyroid-stimulating hormone (TSH) cutoff value, and levothyroxine replacement in frequently encountered issues like subclinical hypothyroidism pregnancy. The study was intended to compare American Thyroid Association (ATA)-2011 defined trimester-specific TSH with conventional values diagnosis newly detected pregnancy, as there are no reference ranges Bangladesh. Methods: This cross-sectional,...
Postmenopausal osteoporosis is a chronic inflammatory disease characterized by decreased bone mass and increased fracture risk. Estrogen deficiency during menopause plays major role in postmenopausal influencing bone, immune, gut cell activity. In the gut, estrogen loss decreases tight junction proteins that bind epithelial cells of intestinal barrier together. This increases permeability alters balance T cells, increasing helper (Th17) decreasing anti-inflammatory regulatory (Tregs)....
Abstract Understanding the phenotypic transitions of cancer cells is crucial for elucidating tumor progression mechanisms, particularly transition from a non-invasive spheroid phenotype to an invasive network phenotype. We developed agent-based model (ABM) using Compucell3D, open-source biological simulation software, investigate how varying biophysical and biochemical parameters influence emerging properties cellular communities, including cell growth, division, migration. Our focus was on...
Abstract Patient-specific premorbidity, age, and sex are significant heterogeneous factors that influence the severe manifestation of lung diseases, including COVID-19 fibrosis. The renin-angiotensin system (RAS) plays a prominent role in regulating effects these factors. Recent evidence shows patient-specific alterations RAS homeostasis concentrations with premorbidity expression level angiotensin-converting enzyme 2 (ACE2) during COVID-19. However, conflicting suggests decreases,...
Objective: To evaluate the clinical and radiological outcome of MTA in nonvital teeth with open apices. Methods: Twenty-five non-vital apices were treated apexification procedure. Standard endodontic procedures followed an apical plug at least 5 mm was created by using after a calcium hydroxide intra-canal dressing for 1 week. Final obturation done 24 hours vertical compaction technique gutta percha. Patients recalled 3, 6, 9 12 months interval. Clinical evaluated assessing pain, tenderness,...
Cell signaling and gene transcription occur at faster time scales compared to cellular death, division, evolution. Bridging these multiscale events in a model is computationally challenging. We introduce framework for the systematic development of cell population models. Using message passing interface (MPI) parallelism, creates from single-cell biochemical network model. It launches parallel simulations on treats each stand-alone process as object. MPI mediates cell-to-cell...
Bone health is determined by factors including bone metabolism or remodeling. Wnt-10b alters osteoblastogenesis through pre-osteoblast proliferation and differentiation osteoblast apoptosis rate, which collectively lead to the increase of density. To model this, we adapted a previously published The resulting for compartment includes differential equations active osteoclasts, pre-osteoblasts, osteoblasts, osteocytes, amount present at remodeling site. Our alterations original consist...
The aim of this report is to discuss a case about traumatized upper left central incisor presented with chronic periapical pathology unusual presentation. In case, the apical area tooth was exposed for long period and apex open due loss affected materials its surrounding bone soft tissue loss. corrected curettage retrograde filling Mineral Trioxide Aggregate (MTA) as well managed pedicle flap design. discolouration mild shortening crown intrusive effect by lamination cosmetic restorative...
Palato-gingival groove is a developmental anomaly often affecting the maxillary lateral incisor. The aim of this presentation to describe clinical management incisor tooth with palato-gingival perio-endo lesion having immature apex. Despite complex anatomy, case was managed by using Mineral Trioxide Aggregate plug technique as non-surgical endodontic treatment. functional without any complication on basis regular and radiological evaluation. DOI: http://dx.doi.org/10.3329/updcj.v2i2.15534...