A5032916070- DNA Repair Mechanisms
- Sirtuins and Resveratrol in Medicine
- Poxvirus research and outbreaks
- Bacterial Infections and Vaccines
- Genomics, phytochemicals, and oxidative stress
- T-cell and B-cell Immunology
- RNA Interference and Gene Delivery
- RNA modifications and cancer
- Immune Cell Function and Interaction
- Herpesvirus Infections and Treatments
- Textile materials and evaluations
- Cell death mechanisms and regulation
- Research in Cotton Cultivation
- Epigenetics and DNA Methylation
- Rabies epidemiology and control
- Orthopedic Infections and Treatments
- Antibiotic Resistance in Bacteria
- Enterobacteriaceae and Cronobacter Research
- Bacterial Genetics and Biotechnology
- Autophagy in Disease and Therapy
Universidade Potiguar
2023
Universidade Federal do Rio Grande do Norte
2014-2021
Oxidative stress generated during inflammation is associated with a wide range of pathologies. Resveratrol (RESV) displays anti-inflammatory and antioxidant activities, being candidate for the development adjuvant therapies several inflammatory diseases. Despite this potential, cellular responses induced by RESV are not well known. In work, transcriptomic analysis was performed following lipopolysaccharide (LPS) stimulation monocyte cultures in presence RESV. Induction an response observed...
The presence of oxidized DNA lesions, such as 7,8-dihydro-8-oxoguanine (8-oxoG) and apurinic/apyrimidinic sites (AP sites), has been described epigenetic signals that are involved in gene expression control. In mammals, Apurinic-apyrimidinic endonuclease 1/Redox factor-1 (APE1/Ref-1) is the main AP base excision repair (BER) pathway active demethylation processes. addition, APE1/Ref-1, through its redox function, regulates several transcriptional factors. However, control targets each APE1...
Meningitis is a contagious infectious disease with high rates of mortality. Most pathogenic microbes in humans have the ability to cause bacterial meningitis. However, most common pathogens are Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae type b (Hib). It was found that susceptibility this may be related genetic characteristics host, such as occurrence single nucleotide polymorphisms (SNPs). In our previous work, association SNPs DNA repair genes meningitis...
Esse trabalho analisa se a hipótese de transmissão sexual por fluidos, da doença Monkeypox, é verdadeira e pode ser considerada prevalente entre as demais formas transmissão. Trata-se uma revisão bibliográfica do tipo integrativa que consultou bases dados PubMed, Biblioteca Virtual em Saúde Scielo, Outubro 2022, comparando artigos publicados 2018 2022. Após etapas triagem, foram incluídos 12 artigos. Os principais resultados agrupados duas categorias: a) sugeriram enquanto via alta...