- Pharmaceutical Practices and Patient Outcomes
- Pharmacovigilance and Adverse Drug Reactions
- Medication Adherence and Compliance
- Diabetes Treatment and Management
- Blood Pressure and Hypertension Studies
- Thyroid Disorders and Treatments
- Antibiotic Use and Resistance
- Atrial Fibrillation Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Pharmaceutical Economics and Policy
- Thyroid Cancer Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Pharmaceutical studies and practices
- Antibiotics Pharmacokinetics and Efficacy
- Parathyroid Disorders and Treatments
- Nutrition and Health in Aging
- Folate and B Vitamins Research
- Cancer Treatment and Pharmacology
- Diabetes Management and Research
- Cardiac Arrhythmias and Treatments
- Hormonal Regulation and Hypertension
- Soft tissue tumor case studies
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
University Hospital Dubrava
2015-2025
University of Zagreb
2014-2025
Diabetes Australia
2024
Unité de Nutrition Humaine
2019
Universidade de São Paulo
2015
Libera Università Internazionale degli Studi Sociali Guido Carli
2015
BACKGROUND: Most diabetic and hypertensive patients, principally the elderly, do not achieve adequate disease control consume 5%-15% of annual health care budgets. Previous studies verified that pharmaceutical is useful for achieving in diabetes hypertension. OBJECTIVE: To evaluate economic cost incremental cost-effectiveness ratio (ICER) per quality-adjusted life-year (QALY) management hypertension elderly patients a primary public system developing country. METHODS: A 36-month randomized...
To examine the effect of a pharmaceutical care program on coronary heart disease risk in elderly diabetic and hypertensive patients.A total 200 (> 60 years) and/or patients were recruited into randomized, controlled, prospective clinical trial with 36-month follow-up, developed public primary health unit municipality Brazilian State Sao Paulo. A range measurements evaluated at baseline up to 36 months afterwards. The intervention group received from pharmacist, whereas control their usual...
Purpose. The primary objective of this study was to investigate the prevalence clinically important potential drug-drug interactions (DDIs) in elderly patients attending public health care system Brazil. secondary possible predictors DDIs. Methods. A cross-sectional carried out 5 Brazilian cities located Ourinhos Micro-region, Sao Paulo State, between November 2010 and April 2011. selected sample divided according presence (exposed) or absence (unexposed) one more DDIs (defined as a minimum...
BackgroundCombined oral contraceptive (COC) use is the most commonly used reversible method of birth control. The incorrect COCs frequent and one common causes unintended pregnancies. Community pharmacists (CPs) are in a strategic position to improve COC because they last health professional interact with patients before drug use. ObjectiveTo evaluate dispensing practices CPs developing country. MethodA cross-sectional study was conducted community pharmacies Assis Ourinhos microregions,...
The aim of the study was to explore (a) prevalence and grade nonalcoholic fatty liver (NAFL) among outpatients referred for abdominal ultrasound (US) examination (b) relationship between presence severity steatosis metabolic syndrome (MS). This a retrospective analysis patients without history disease examined by US in University hospital setting. used detect semiquantitatively (0-3) steatosis. Data on patients' age, gender, body mass index (BMI), impaired glucose metabolism (IGM),...
To evaluate the clinical pharmacist-led medication reconciliation process in practice by quantifying and analyzing unintentional discrepancies at hospital admission.An observational prospective study was conducted Clinical Department of Internal Medicine, University Hospital Dubrava, during a 1-year period (October 2014 - September 2015) as part implementation Safe Practice, Medication Reconciliation European Network for Patient Safety Quality Care Joint Action (PASQ JA) project. Patients...
SUMMARY: A case of mesalazine‐induced acute interstitial nephritis (AIN) in a 41‐year‐old patient with ulcerative colitis (UC) is reported here. Clinical symptoms such as fever and arthralgia, laboratory findings eosinophilia renal failure suggested AIN, which was confirmed by biopsy. With withdrawal mesalazine intravenous methylprednisolone the patient's function recovered. It observed that early discontinuation associated amelioration most patients, so recommendation patients receiving...
As a cost-saving measure, the Drug and Therapeutics Committee (DTC) removed ceftriaxone from list of restricted antibiotics in May, 2008, which permitted its use as first-line antibiotic. To evaluate impact this change, occurrence extended-spectrum beta-lactamase (ESBL)-positive bacterial strains antibiotic consumption were monitored for 2 years before after intervention. In post-intervention period, utilization increased, while total did not change significantly. The all decreased (p <0.05)...
Aims. To investigate morbidity and mortality in a real-life cohort of patients with type 2 diabetes (T2D) relation to prevalence severity nonalcoholic fatty liver disease (NAFLD). Methods. Patients T2D were referred for assessment fibrosis by the FIB-4 test stiffness measurement (LSM) vibration-controlled transient elastography (VCTE). Liver steatosis was quantified controlled attenuation parameter (CAP). These followed until death or censored date. Results. Among 454 (52% males, mean age...
Objective To understand primary care physicians’ perspectives on academic detailing from an antimicrobial stewardship team to combat antibiotic overuse for upper respiratory infections and bronchitis in the COVID-19 era, which will help prevent avoidable outpatient visits. Methods In this prospective study, 14 female Croatian physicians completed standardized qualitative interviews using a semi-structured guide. The data were analyzed inductive methodology based reflexive thematic analysis....
To evaluate the impact of pharmacotherapeutic education on 30-day post-discharge medication adherence and adverse outcomes in patients with type 2 diabetes mellitus (T2DM).The prospective, randomized, single-center study was conducted at Medical Department University Hospital Dubrava, Zagreb, between April June 2018. One hundred thirty adult T2DM who were discharged to community randomly assigned either intervention or control group. Both groups during hospital stay received usual education....
The aim of this study was to evaluate the incidence and type adverse drug reactions (ADRs) identify risk factors for ADRs in elderly patients within 30 days following discharge from an internal medicine clinic.A prospective observational conducted at Internal Medicine Clinic University Hospital Dubrava, Zagreb, Croatia, between September 1(st) November 30(th) 2012. Patients aged ≥ 65 years discharged clinic during period were eligible inclusion study. follow-up visit scheduled ~ after...