BACKGROUND The sensitivity of cytology for the detection urothelial carcinoma (UC) is limited. Newer methods such as fluorescence in situ hybridization (FISH), immunocytology (uCyt+), and protein markers have been developed to improve urine‐based UC. As only little known regarding combined application these markers, we investigated whether combinations 4 most broadly available tests (cytology, FISH, uCyt+, nuclear matrix 22 [NMP22‐ELISA]) may their diagnostic performance. METHODS study was...

Background: The classification of fractures is necessary to ensure a reliable means communication for clinical interaction, research, and education. Distal humeral coronal plane shear (CSF) are very rare in the growing-age population, despite that multiple schemes exist. Objective: aim this study was assess inter- intra-rater reliability 4 most commonly used CSF classifications their role guiding treatment decisions everyday practice. Materials methods: 51 patients with were retrospectively...

Abstract To determine dose-optimized image acquisition parameters for good quality (IQ) in neonatal chest radiography with a computed (CR) CsBr needle detector vs. wireless digital (DR) CsI using different doses and filters. Physical resolution of the two detectors unprocessed imaging contrast-detail phantom was automatically evaluated. Post-processed radiographic used Visual Grading Analysis (VGA) by three radiology raters. Different kVp, mAs, filter settings were used. The VGA score (VGAS)...

The role of urine markers in the surveillance patients with non-muscle invasive bladder cancer (NMIBC) is discussed extensively. In case negative cystoscopy additional prognostic value these has not been clearly defined yet. present study first systematic approach to directly compare ability a marker panel predict risk recurrence and progression (BC) no evidence relapse during for NMIBC. One hundred fourteen who underwent testing NMIBC had BC were included. For all cytology,...

Abstract Objective To identify textural features on dual-energy CT (DECT)–based bone marrow images in myeloma which correlate with serum markers of activity and the degree medullary involvement. Methods A total 110 patients (63.0 ± 11.0 years, 51 female) who underwent unenhanced whole-body DECT between September 2015 February 2019 were retrospectively included, was approved by our institutional ethics committee a waiver informed consent requirement. All had current hematologic laboratory...

Background . The optimal use of urine markers in the surveillance non-muscle-invasive bladder cancer (NMIBC) remains unclear. Aim present study was to investigate combined and stepwise four most broadly available detect tumor recurrence patients undergoing NMIBC. Patients Methods 483 with history NMIBC were included. Cytology, UroVysion, fluorescence situ hybridization (FISH), immunocytology (uCyt+), NMP22 ELISA performed before cystoscopy. Characteristics single tests combinations assessed...

Abstract Objectives Computed tomography (CT) imaging of the clavicula displays reference standard for forensic bone age diagnostics in adolescents and young adults. Consequently, highest efforts on radiation reduction are warranted. Therefore, aim this study was to investigate feasibility low-dose (LD) CT estimation living adolescents. Methods A total 207 non-contrast chest 144 patients born between 1988 2012, performed 2018 due various clinical indications, were included retrospective...

Objectives . To assess the performance of urine markers determined in samples from bladder compared to collected upper urinary tract (UUT) for diagnosis UUT urothelial carcinoma (UC). Patients and Methods The study comprised 758 either (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>373</mml:mn></mml:math>) or id="M2"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>385</mml:mn></mml:math>). All patients underwent urethrocystoscopy...

(1) This study evaluates the impact of an AI denoising algorithm on image quality, diagnostic accuracy, and radiological workflows in pediatric chest ultra-low-dose CT (ULDCT). (2) Methods: 100 consecutive thorax ULDCT were included reconstructed using weighted filtered back projection (wFBP), iterative reconstruction (ADMIRE 2), (PixelShine). Place-consistent noise measurements used to compare objective quality. Eight blinded readers independently rated subjective quality a Likert scale (1...

Abstract Background To assess the feasibility and possible value of semi-automated diffusion weighted imaging (DWI) volumetry whole neuroblastic tumors with apparent coefficient (ADC) map evaluation after neoadjuvant chemotherapy. Methods Pediatric patients who underwent surgical resection at our institution from 2013 to 2019 received a preoperative MRI scan DWI chemotherapy were included. Tumor volume was assessed approach in using dedicated software prototype. Quantitative ADC values...

To analyze possible influencing factors on radiation exposure in pediatric chest CT using different approaches for dose optimization and to determine major indicators development. In this retrospective study at a clinic with maximum care facilities including radiology, 1695 examinations 768 patients (median age: 10 years; range: 2 days 17.9 years) were analyzed. Volume indices, effective dose, size-specific estimate, automatic modulation (AEC), high-pitch protocols (pitch ≥ 3.0) evaluated by...

To assess the effectiveness of whole-body MRI (WB-MRI) in early diagnosis chronic recurrent multifocal osteomyelitis (CRMO) and prediction clinical response through quantitative features.20 children (mean age, 10.3 years; range, 5-14 years) with CRMO underwent WB-MRI were assessed a score (Jansson) at baseline (median time after first encounter, 8 months) follow-up baseline, 11.5 months). Baseline scans classified as (within 6 months encounter) late. Clinical responders non-responders...

Pediatric radial neck and head fractures are rare, accounting for only 1% of all in children. The aim this study is to describe the management results respective fracture types different injury characteristics.This performs a retrospective data analysis 100 consecutive patients with proximal radius treated single high-volume pediatric trauma center.One hundred [mean age 7.5 years (1-15)] were documented between 3/2011 12/2019. gender distribution was 62 girls 38 boys. Twenty-seven had...

To analyze patterns of response in soft tissue sarcomas exposed to pazopanib using CT-morphologic and textural features their suitability for evaluating therapeutic response.Retrospective evaluation CT texture 33 patients (23 female; mean age: 61.2 years, range, 30-85 years) with treated from October 2008 July 2017. Response was based on modified (m)CHOI-criteria RECISTv.1.1 classified as partial (PR), stable disease (SD), progressive (PD). The following CT-texture (CTTA)-parameters were...

Diffusion-weighted images of the prostate can suffer from a "hazy" background in low signal-intensity areas. We hypothesize that enhanced image processing (EIP) using complex averaging reduces artifacts, noise, and distortion conventionally acquired diffusion-weighted synthesized high b-value images, thus leading to higher quality better detection potentially malignant lesions. Conventional DWI trace with 1000 s/mm2 (b1000), calculated 2000 (cb2000), ADC maps 3T multiparametric MRIs 53...

Aim Data on the depth of nasal intubation in neonates are rare, although this is preferred route some countries. Therefore, recommendations optimal depths based gestational age (GA) and weight desirable. Methods We determined distances between middle thoracic vertebrae 2 (T2) tip endotracheal tube 116 X-rays from nasally intubated neonates. The (tip to nostril distance) that was documented digital patient’s file then corrected for distance reach an insertion depth. Results were plotted...

The aim of this study was to compare image quality anatomical cardiac details without electrocardiography triggering, sedation, or heart rate-regulating drugs in contrast-enhanced pediatric chest computed tomography (CT), using high-pitch CT (HPCT) versus conventional pitch-mode technique (multidetector [MDCT]).After written informed consent, 55 patients (median age, 11 years; range, 3-17 years) were prospectively included institutional review board-approved study. Patients underwent...

Treatment of neuroblastoma metastases usually consists chemotherapy and irradiation. However, in selected cases, surgical treatment is also indicated. In this study, we present three cases patients with at rare sites that underwent surgery.We retrospectively analyzed data who surgery for our department Pediatric Surgery Urology the University Children's Hospital Tuebingen those had explicitly a metastasis.Between 2002 2020, 277 children neuroblastoma. Three exceptional are presented here...

Computed tomography (CT) as a fast and reliable diagnostic technique is the imaging modality of choice for acute bowel ischemia. However, often difficult mainly due to low attenuation differences between ischemic perfused segments.To compare efficacy new post-processing tool based on frequency selective non-linear blending with that conventional linear contrast-enhanced CT (CECT) image detection ischemia.Twenty-seven consecutive patients (19 women; mean age = 73.7 years, range 50-94 years)...

The aim of this study was to evaluate the performance an automated workflow for multiparametric magnetic resonance imaging (mpMRI) prostate compared with a manual mpMRI workflow.This retrospective approved by local ethics committee. Two MR technicians scanned 2 healthy volunteers prototypical highly (Siemens Healthineers GmbH, Erlangen, Germany) and manually adjusted scan protocol each. Thirty patients (mean age ± standard deviation, 68 11 years; range, 41-93 years) suspected cancer...