A5079658285- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Nail Diseases and Treatments
- Bacteriophages and microbial interactions
- Animal Virus Infections Studies
- Microbial infections and disease research
- Yeasts and Rust Fungi Studies
- Plant Pathogens and Fungal Diseases
- Science and Education Research
- Oral and gingival health research
- Phytoplasmas and Hemiptera pathogens
- HIV/AIDS oral health manifestations
- Plant Pathogens and Resistance
- Women's cancer prevention and management
- Amoebic Infections and Treatments
Universidade Federal do Triângulo Mineiro
2013-2023
Cryptococcosis is an important fungal infection in immunocompromised individuals, especially those infected with HIV. In Brazil, despite the free availability of antiretroviral therapy (ART) public health system, mortality rate due to Cryptococcus neoformans meningitis still high. To obtain a more detailed picture population genetic structure this species southeast we studied 108 clinical isolates from 101 patients and 35 environmental isolates. Among patients, 59% had fatal outcome mainly...
Cryptococcal infections are mainly caused by members of the Cryptococcus neoformans species complex (molecular types VNI, VNII, VNB, VNIV and AD hybrid VNIII). PCR mating type loci MLST typing using ISHAM-MLST consensus scheme were used to evaluate genetic relationship 102 (63 clinical 39 environmental) C. isolates from Uberaba, Brazil correlate obtained genotypes with clinical, antifungal susceptibility virulence factor data. All alpha. identified 12 known five new sequence (ST). Fourteen...
Entamoeba gingivalis is considered an oral commensal but demonstrates a pathogenic potential associated with periodontal disease in immunocompromised individuals. Therefore, this study evaluated the occurrence, opportunistic conditions, and intraspecific genetic variability of E. HIV(+)/AIDS patients. was studied using fresh examination (FE), culture, PCR from bacterial plaque samples collected 82 Genetic characterization lower ribosomal subunit region 18S (18S-SSU rRNA) conducted 9 positive...
Background Although Cryptococcus laurentii has been considered saprophytic and its taxonomy is still being described, several cases of human infections have already reported. This study aimed to evaluate molecular aspects C. isolates from Brazil, Botswana, Canada, the United States. Methods In this study, 100 phenotypically identified were evaluated by sequencing 18S nuclear ribosomal small subunit rRNA gene (18S-SSU), D1/D2 region 28S large (28S-LSU), internal transcribed spacer (ITS)...
Abstract Among Cryptococcus gattii genotypes, VGII has gained pivotal relevance in epidemiological, clinical and genetic contexts due to its association with several outbreaks temperate regions the high variability of this genotype. The aim study was compare 25 isolates C. from Southeast region Brazil previously described other country around world. isolates, 24 were one VGI. All them newly identified. Three new allele types (AT) (AT47 for URA5 locus, AT56 LAC1 AT96 IGS1 region) also...
In recent decades, emerging fungal infections have changed the clinical mycology scenario as a consequence of advances in medical diagnostics and therapeutic procedures, long hospitalization times, growing number individuals with debilitating chronic diseases impaired immune systems. This report presents 19 months old Brazilian female patient who developed severe sepsis by an uncommon yeast. She was admitted at intensive care unit pneumonia, bronchopulmonary dysplasia, weight-for-age z score...
Statins are used as cholesterol-lowering drugs and may also have direct antimicrobial effects.To evaluate synergic interactions between simvastatin both amphotericin B fluconazole, against environmental strains of Cryptococcus neoformans isolated from captive birds' droppings.Experimental study conducted at Federal University Piauí, Parnaíba, in collaboration with Triângulo Mineiro, Uberaba, Brazil.Statin susceptibility tests samples were performed prescribed standards. Interactions...
Abstract Phage display (PD) is a tool for developing new molecules to control pathogens. Peptides selected by PD are commonly synthesised and tested, but the use of phage M13 displaying peptides as direct biding in intestinal tract has not yet been tested. This study evaluated whether can remain viable chicken gastrointestinal it causes injury or humoral immune response. We inoculated E. coli ER2738 (ECR) infected with into birds at different ages. found virus faeces 5 13 days after...
Data about the relationship between their molecular types, virulence factors, clinical presentation, antifungal susceptibility profile, and outcome are still limited for Cryptococcus deuterogattii. This study aimed to evaluate phenotypic characteristics of 24 C. deuterogattii isolates from southeast region Brazil. The characterization was performed by multilocus sequence typing (MLST). profile obtained according CLSI-M27-A3 EUCAST-EDef 7.1 methods. factors were evaluated using classic...
Abstract Phage display (PD) is a tool for developing new molecules to control pathogens. Peptides selected by PD are commonly synthesised and tested, but the use of phage M13 displaying peptides as direct biding in intestinal tract has not yet been tested. This study evaluated whether can remain viable chicken gastrointestinal it causes injury or humoral immune response. We inoculated E. coli ER2738 (ECR) infected with into birds at different ages. found virus faeces 5 13 days after...