A5052793874- Malaria Research and Control
- Mosquito-borne diseases and control
- Obesity, Physical Activity, Diet
- Travel-related health issues
- Parasites and Host Interactions
- Birth, Development, and Health
- Nutritional Studies and Diet
- Disaster Response and Management
- Global Maternal and Child Health
- Parasite Biology and Host Interactions
- Resilience and Mental Health
- Posttraumatic Stress Disorder Research
- Global Public Health Policies and Epidemiology
- Child Nutrition and Water Access
- Maternal Mental Health During Pregnancy and Postpartum
- Genetic diversity and population structure
- Mitochondrial Function and Pathology
- Aquatic Ecosystems and Biodiversity
- Amyotrophic Lateral Sclerosis Research
- Pharmacogenetics and Drug Metabolism
- Zoonotic diseases and public health
- Vibrio bacteria research studies
- Cognitive and psychological constructs research
- Pacific and Southeast Asian Studies
- Forensic Anthropology and Bioarchaeology Studies
Osaka Metropolitan University
2022-2025
Tokyo Metropolitan University
2022-2024
Metropolitan University
2023-2024
Osaka International University
2024
Osaka City University
2019-2021
Binghamton University
2006-2021
Karolinska Institutet
2014-2019
National Institute of Economic Research
2017
State University of New York
2007
Abstract Kenya is intensifying its national efforts in malaria control to achieve elimination. Detailed characterization of infection among populations living the areas where disease endemic a crucial priority, especially for planning and evaluating future elimination strategy. This study aimed investigate distribution extent on islands Lake Victoria aid designing new interventions Five cross-sectional surveys were conducted between January 2012 August 2014 four (Mfangano, Takawiri, Kibuogi...
Introduction Malaria is still a major health problem in sub-Saharan Africa, where 98% of global malaria mortality occurs. In addition, the spread Plasmodium falciparum with partial artemisinin resistance East Africa and beyond great concern. The establishment more effective vector control, addition to current long-lasting insecticide-treated net distribution programme, an urgent task these areas. One novel control candidate pyrethroid-PBO ceiling nets (OlysetPlus nets) which can overcome...
Abstract The South Pacific archipelago of Vanuatu, like many developing countries, is currently experiencing a shift in disease burdens from infectious to chronic diseases with economic development. A rapid increase obesity prevalence represents one component this “health transition.” Objective: To identify behaviors associated measures Vanuatu. Design and Methods: Five hundred thirty four adults three islands varying level development were surveyed. Height, weight, waist, hip...
Abstract Background Five years after successful malaria elimination, Aneityum Island in Vanuatu experienced an outbreak of Plasmodium vivax unknown origin 2002. Epidemiological investigations revealed several potential sources P. . We aimed to identify the genetic responsible for resurgence. Methods microsatellite markers were genotyped using DNA extracted from archived blood samples. A total 69 samples four populations was included: 29 2002, seven 1999 and 2000, 18 visitors 15 nearby Tanna...
Health patterns are changing in developing countries; as diet and activity change with economic development, chronic disease prevalence increases, which is a characteristic of health transition. The islands Vanuatu (South Pacific) have varying rates development provide natural experimental model transition.To characterize behavioral changes associated modernization.We surveyed 425 children 559 adults on three degree development. We assessed (24-h dietary recall), physical (mode transport,...
Abstract Background: Archaeological and linguistic evidence suggests the Marianas Islands were settled around 3,600 years before present (ybp) from Island Southeast Asia (ISEA). Around 1,000 ybp latte stone pillars first of rice cultivation appear in Marianas. Both traditions are absent rest prehistoric Oceania. Objective: To examine genetic origins postsettlement gene flow Chamorros Islands. Methods: infer we analyzed ∼360 base pairs hypervariable‐region 1 (HVS1) mitochondrial DNA 105 Guam,...
Seroepidemiology can provide evidence for temporal changes in malaria transmission and is an important tool to evaluate the effectiveness of control interventions. During early 2000s, Vanuatu experienced acute increase incidence due a lapse funding vector control. After distribution subsidised insecticide-treated nets (ITNs) resumed 2003, decreased subsequent years. This study was conducted find serological supporting impact ITN on exposure Anopheles bites parasite prevalence.On Ambae...
Abstract Background Long-lasting insecticidal nets (LLIN) and vaccines are effective malaria control tools. However, inadequate uptake has been reported in countries where both interventions available. To maximize the impact these tools provide, it is crucial to identify populations that not being reached barriers uptake. Methods In a cross-sectional study conducted April 2024 Kanyamwa Kologi Ward Homa Bay County, Kenya, 4,662 households 58 randomely selected villages were visited...
Abstract Objective Rapid economic development and subsequent changes in lifestyle disease burdens (‘health transition’) is associated with increasing prevalence of obesity among both adults children. However, because continued infectious diseases undernutrition during the early stages transition, monitoring childhood has not been prioritized many countries scope problem unknown. Therefore we sought to characterize patterns overweight an transitional area, South Pacific archipelago Vanuatu....
Objective The Republic of Vanuatu, similar to other South Pacific island nations, is undergoing a rapid health transition as consequence modernization. pace modernization uneven across Vanuatu's 63 inhabited islands, resulting in differential impacts on overall body composition and prevalence obesity among between men women. In this study, we investigated (1) how adult male female Melanesians living four islands varying economic development (2) differs Polynesians rural Vanuatu. Methods...
As markers of exposure anti-malaria antibody responses can help characterise heterogeneity in malaria transmission. In the present study to Plasmodium falciparum AMA-1, MSP-119 and CSP were measured with aim describe transmission patterns meso-endemic settings Lake Victoria. Two cross-sectional surveys conducted Victoria January August 2012. The area comprised three settings: mainland (Ungoye), large island (Mfangano) small islands (Takawiri, Kibuogi, Ngodhe). Individuals provided a...
Abstract Although WHO recommends mass drug administration (MDA) for malaria elimination, further evidence is required understanding the obstacles optimum implementation of MDA. Just before long rain in 2016, two rounds MDA with artemisinin/piperaquine (Artequick) and low-dose primaquine were conducted a 35-day interval entire population Ngodhe Island (~500 inhabitants) Lake Victoria, Kenya, which surrounded by areas moderate high transmission. With approximately 90% compliance, Plasmodium...
Malaria control initiatives require rapid and reliable methods for the detection monitoring of molecular markers associated with antimalarial drug resistance in Plasmodium falciparum parasites. Ngodhe island, Kenya, presents a unique malaria profile, lower P. incidence rates than surrounding region, high proportion sub-microscopic low-density infections. Here, using custom dual-indexing Illumina next generation sequencing, we generate profiles on seventy asymptomatic infections from mass...
Abstract Objective The present study evaluates the use of multiple correspondence analysis (MCA), a type exploratory factor designed to reduce dimensionality large categorical data sets, in identifying behaviours associated with measures overweight/obesity Vanuatu, rapidly modernizing Pacific Island country. Design Starting seventy-three true/false questions regarding variety behaviours, MCA identified twelve most significantly modernization status and transformed aggregate binary responses...
Abstract Characterising the genomic variation and population dynamics of Plasmodium falciparum parasites in high transmission regions Sub-Saharan Africa is crucial to long-term efficacy regional malaria elimination campaigns eradication. Whole-genome sequencing (WGS) technologies can contribute towards understanding epidemiology structural landscape P. populations, including those within Lake Victoria basin, a region intense transmission. Here we provide baseline assessment diversity...
Rapid diagnosis of malaria using acridine orange (AO) staining and a light microscope with halogen lamp interference filter was deployed in some malaria-endemic countries. However, it has not been widely adopted because: (1) the weak as an excitation set-up did work well under unstable power supply; and, (2) samples frequently inconsistent. The replaced by low-cost, blue light-emitting diode (LED) lamp. Using reformulated AO solution, protocol revised to make use concentration gradient...
Abstract Background In the Lake Victoria Basin of western Kenya, malaria remains highly endemic despite high coverage interventions such as insecticide-impregnated long-lasting insecticidal nets (LLIN). The malaria-protective effect LLINs is hampered by insecticide resistance in Anopheles vectors and its repurposing community. Ceiling LLIN with synergist piperonyl butoxide (PBO-LLIN) are novel tools that can overcome problems behavioral variation net use metabolic to insecticide,...
Understanding the transmission and movement of Plasmodium parasites is crucial for malaria elimination prevention resurgence. Located at limit in Pacific, Vanuatu an ideal candidate programs due to low endemicity isolated nature its island setting. We analyzed variation merozoite surface protein 1 (msp1) circumsporozoite (csp) P. falciparum vivax populations examine patterns gene flow population structures among seven sites on five islands Vanuatu. Genetic diversity was general higher than...
The Republic of Vanuatu, like many developing nations, is undergoing a rapid health transition. Our previous study identified several behavioral risk factors for the rising prevalence obesity. Unexpectedly, daily time spent using television and radio was revealed as protective factor obesity in 2007. In this study, we sought to explore associations between ownership consumer electronics (CE) measures adiposity Vanuatu 2011.We surveyed 873 adults from five islands varying level economic...
Abstract Background Simple and accurate diagnosis is a key component of malaria control programmes. Microscopy the current gold standard, however it requires extensive training results largely rely on skill microscopists. Malaria rapid diagnostic tests (RDT) can be performed with minimal offer timely diagnosis, but are not quantitative. Moreover, some Plasmodium falciparum parasites have evolved no longer detected by existing RDT. Developed Sysmex Corporation, XN-31 prototype (XN-31p) an...
Abstract Background Past studies show relationships between disaster-related displacement and adverse psychosocial health outcomes. The development of interventions following is thus increasingly prioritized. However, data from low- middle-income countries (LMICs) are lacking. In October 2017, the population Ambae Island in Vanuatu, a lower-middle income country, was temporarily displaced due to volcanic activity. We analyzed distress among adults event differences based on support they...