Enhancement, followed by segmentation, quantification and modelling of blood vessels in retinal images plays an essential role computer-aided retinopathy diagnosis. In this paper, we introduce the bowler-hat transform method a new approach based on mathematical morphology for vessel enhancement. The proposed combines different structuring elements to detect innate features vessel-like structures. We evaluate qualitatively quantitatively compare it with state-of-the-art methods using both...

Abstract Three-dimensional fluorescence time-lapse imaging of the beating heart is extremely challenging, due to heart’s constant motion and a need avoid pharmacological or phototoxic damage. Although real-time triggered can computationally “freeze” for 3D imaging, no previous algorithm has been able maintain phase-lock across developmental timescales. We report new capable maintaining day-long phase-lock, permitting routine acquisition synchronised + time video datasets zebrafish heart....

Radiation-induced fatigue is a common side effect of breast cancer radiotherapy (RT). This study compares the induction and persistence radiation-induced in accelerated partial irradiation (APBI), hypofractionated RT, standard whole RT.Eighty patients were treated with novel, 3-week regimen 333 centigrays (cGy) for 15 fractions to 4995 cGy; these, 45 using APBI, whereas 35 RT. These matched receiving 200 cGy 30 irradiation. Fatigue score, Common Terminology Criteria Adverse Events version...

The 'Bridging Imaging Users to Analysis' survey was conducted in 2022 by the Center for Open Bioimage Analysis (COBA), BioImaging North America (BINA) and Royal Microscopical Society Data Section (RMS DAIM) understand needs of imaging community. Through multichoice open-ended questions, inquired about demographics, image analysis experiences, future suggestions on role tool developers users. Participants were from diverse roles domains life physical sciences. To our knowledge, this is first...

Runways are vital descriptive features of airports and knowledge their location is important to many aviation military applications. With the recent wide availability remote sensing data, there demand for an automatic process extracting runway geometry from satellite imagery. In particular, Very High Resolution (VHR) data makes it feasible extract a runway's area precisely. this paper we establish novel method accurate precise extraction geometric polygons arbitrary number runways in VHR...

Helical objects occur in medicine, biology, cosmetics, nanotechnology, and engineering. Extracting a 3D parametric curve from 2D image of helical object has many practical applications, particular being able to extract metrics such as tortuosity, frequency, pitch. We present method that is straighten the derive robust peaks boundary. The algorithm small number stable parameters require little tuning, validated against both synthetic real-world data. results show extracted comes within close...

Breast lymphedema has supplanted upper extremity as a common and debilitating sequela of breast cancer treatment, but no objective measurement. We assessed the utility ultrasound-measured difference in dermal thickness between affected unaffected breasts measure lymphedema. associated this with patient characteristics, treatment parameters, patient-reported impact on quality life.We enrolled 30 invasive carcinoma patients treated breast-conserving surgery, sentinel lymph node biopsy,...

A wide range of biomedical applications require enhancement, detection, quantification and modelling curvilinear structures in 2D 3D images. Curvilinear structure enhancement is a crucial step for further analysis, but many the approaches still suffer from contrast variations noise. This can be addressed using multiscale approach that produces better quality low noisy images compared with single-scale Here, we propose Multiscale Top-Hat Tensor (MTHT) approach, which combines morphological...

AMA Zhang M, Chen T, Kim L, et al. Original paperThree-dimensional dosimetric considerations from different point A definitions in cervical cancer low-dose-rate brachytherapy. Journal of Contemporary Brachytherapy. 2013;5(4):222-226. doi:10.5114/jcb.2013.38836. APA Zhang, M., Chen, T., Kim, L., Nelson, C., Gabel, & Narra, V. (2013). Brachytherapy, 5(4), 222-226. https://doi.org/10.5114/jcb.2013.38836 Chicago Miao, Ting Leonard H. Carl Molly Venkat and Bruce Haffty 2013. "Original...

There is a paucity of data regarding factors affecting enrollment onto radiation oncology clinical trials. The purpose this study was to determine patients and tumor characteristics that influenced breast cancer hypofractionated radiotherapy trials (HBRTs) at single institution. In retrospective cohort study, enrolled on HBRTs the Rutgers Cancer Institute New Jersey (n = 132) were compared with eligible for, but not treated during same time period 132). Charts retrospectively reviewed...

Blobs and curves occur everywhere in plant bioimaging: from signals of fluorescence-labelled proteins, through cytoskeletal structures, nuclei staining cell extensions such as root hairs. Here we look at the problem colocalisation blobs with (protein-protein colocalisation) (organelle-cytoskeleton colocalisation). This article demonstrates a clear quantitative alternative to pixel-based methods and, using object-based methods, can quantify not only level but also distance between objects....

ABSTRACT The “Bridging Imaging Users to Analysis” survey was conducted in 2022 by the Center for Open Bioimage Analysis (COBA), Bioimaging North America (BINA), and Royal Microscopical Society Data Section (RMS DAIM) understand needs of imaging community. Through multi-choice open-ended questions, inquired about demographics, image analysis experiences, future needs, suggestions on role tool developers users. Participants were from diverse roles domains life physical sciences. To our...

We present a segmentation software package primarily targeting medical and biological applications, with high level of visual feedback several usability enhancements over existing packages. Specifically, we provide substantially faster GPU implementation the local Gaussian distribution fitting energy model, which can segment inhomogeneous objects poorly defined boundaries as often encountered in biomedical images. also interactive brushes to guide process semiautomated framework. The speed...

Enhancement and detection of 3D vessel-like structures has long been an open problem as most existing image processing methods fail in many aspects, including a lack uniform enhancement between vessels different radii at the junctions. Here, we propose method based on mathematical morphology to enhance biomedical images. The proposed method, bowler-hat transform, combines sphere line structuring elements structures. is validated synthetic real data compared with state-of-the-art methods. Our...

How do you use imaging to analyse the development of heart, which not only changes shape but also undergoes constant, high-speed, quasi-periodic changes? We have integrated ideas from prospective and retrospective optical gating capture long-term, phase-locked developmental time-lapse videos. In this paper we demonstrate success approach over a key time period: heart looping, where large in prevent previous approaches capturing comparison with other vivo highlight importance collecting most...

Abstract Three-dimensional fluorescence time-lapse imaging of structural, cellular and sub-cellular processes in the beating heart is an increasingly achievable goal using latest computational techniques. However, previous approaches have had significant limitations. Temporarily arresting drugs disrupts heart’s physiological state, use ultra-high frame-rates for image acquisition causes phototoxic cell damage. Real-time triggered imaging, synchronized to a specific phase cardiac-cycle, can...