Patricia Ryan
A5017998778- Respiratory viral infections research
- Influenza Virus Research Studies
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- COVID-19 and healthcare impacts
- Food Safety and Hygiene
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Streptococcal Infections and Treatments
- Long-Term Effects of COVID-19
- Corporate Finance and Governance
- Chronic Disease Management Strategies
- COVID-19 epidemiological studies
- COVID-19 Impact on Reproduction
- Animal Disease Management and Epidemiology
- Neurogenetic and Muscular Disorders Research
- Protease and Inhibitor Mechanisms
- Telemedicine and Telehealth Implementation
- Primary Care and Health Outcomes
- Connective tissue disorders research
- Diabetes Management and Education
- SARS-CoV-2 and COVID-19 Research
- Data-Driven Disease Surveillance
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
Maryland Department of Health
2015-2025
Association for Computing Machinery
2008-2024
Colorado State University
2000-2023
Georgia Department of Public Health
2014-2023
Minnesota Department of Health
2014-2023
Emory University
2023
Rockefeller University
1997-2022
Hunter College
2013-2022
Centers for Disease Control and Prevention
2010-2021
Oregon Health Authority
2010-2021
Since SARS-CoV-2, the novel coronavirus that causes disease 2019 (COVID-19), was first detected in December (1), approximately 1.3 million cases have been reported worldwide (2), including 330,000 United States (3). To conduct population-based surveillance for laboratory-confirmed COVID-19-associated hospitalizations States, COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) created using existing infrastructure of Influenza (FluSurv-NET) (4) and Respiratory Syncytial Virus...
Between July 2003 and December 2007, the Veterans Health Administration (VHA) introduced a national home telehealth program, Care Coordination/Home Telehealth (CCHT). Its purpose was to coordinate care of veteran patients with chronic conditions avoid their unnecessary admission long-term institutional care. Demographic changes in population necessitate VHA increase its noninstitutional (NIC) services 100% above 2007 level provide for 110,000 NIC by 2011. By 2011, CCHT will meet 50% VHA's...
COVID-NET conducts population-based surveillance for laboratory-confirmed COVID-19-associated hospitalizations in 99 counties † 14 states (California, Connecticut, Colorado, Georgia, Iowa, Maryland, Michigan, Minnesota, New Mexico, York, Ohio, Oregon, Tennessee, and Utah), representing all 10 U.S. Department of Health Human Services regions (2,3).Laboratory-confirmed COVID-19associated among residents a predefined catchment area who had positive SARS-CoV-2 molecular test during...
The surface of Streptococcus pneumoniae is decorated with a family choline‐binding proteins (CBPs) that are non‐covalently bound to the phosphorylcholine teichoic acid. Two examples (PspA, protective antigen, and LytA, major autolysin) have been well characterized. We identified additional CPBs characterized new CBP, CbpA, as an adhesin determinant virulence. Using choline immobilized on solid matrix, mixture from pspA ‐deficient strain pneumococcus was eluted in choline‐dependent fashion....
Prospective cohort study to characterize the clinical features and course of spinal muscular atrophy type I (SMA-I).Patients were enrolled at 3 sites followed for up 36 months with serial clinical, motor function, laboratory, electrophysiologic outcome assessments. Intervention was determined by published standard care guidelines. Palliative options offered.Thirty-four 54 eligible subjects SMA-I (63%) 50% these completed least 12 follow-up. The median age reaching combined endpoint death or...
Pregnant women might be at increased risk for severe coronavirus disease 2019 (COVID-19) (1,2). The COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) (3) collects data on hospitalized pregnant with laboratory-confirmed SARS-CoV-2, the virus that causes COVID-19; to date, such have been limited. During March 1-August 22, 2020, approximately one in four aged 15-49 years COVID-19 was pregnant. Among 598 COVID-19, 54.5% were asymptomatic admission. 272 who symptomatic hospital...
Abstract Background Data on risk factors for coronavirus disease 2019 (COVID-19)–associated hospitalization are needed to guide prevention efforts and clinical care. We sought identify independently associated with COVID-19–associated hospitalizations. Methods Community-dwelling adults (aged ≥18 years) in the United States hospitalized laboratory-confirmed COVID-19 during 1 March–23 June 2020 were identified from COVID-19–Associated Hospitalization Surveillance Network (COVID-NET), a...
To characterize the natural history of spinal muscular atrophy type 2 and 3 (SMA 2/3) beyond 1 year to report data on clinical biological outcomes for use in trial planning.
Foodborne diseases represent a major health problem in the United States.The Diseases Active Surveillance Network (FoodNet) of CDC's Emerging Infections Program monitors cases laboratory-diagnosed infection caused by eight pathogens transmitted commonly through food 10 U.S. sites.*This report summarizes preliminary 2018 data and changes since 2015.During 2018, FoodNet identified 25,606 infections, 5,893 hospitalizations, 120 deaths.The incidence most infections is increasing, including those...
<h3>Importance</h3> Racial and ethnic minority groups are disproportionately affected by COVID-19. <h3>Objectives</h3> To evaluate whether rates of severe COVID-19, defined as hospitalization, intensive care unit (ICU) admission, or in-hospital death, higher among racial compared with non-Hispanic White persons. <h3>Design, Setting, Participants</h3> This cross-sectional study included 99 counties within 14 US states participating in the COVID-19–Associated Hospitalization Surveillance...
Foodborne diseases represent a substantial public health concern in the United States. CDC's Diseases Active Surveillance Network (FoodNet) monitors cases reported from 10 U.S. sites* of laboratory-diagnosed infections caused by nine enteric pathogens commonly transmitted through food. This report describes preliminary surveillance data for 2016 on and changes incidences compared with 2013-2015. In 2016, FoodNet identified 24,029 infections, 5,512 hospitalizations, 98 deaths these pathogens....
Clinical trials of COVID-19 vaccines currently authorized for emergency use in the United States (Pfizer-BioNTech, Moderna, and Janssen [Johnson & Johnson]) indicate that these have high efficacy against symptomatic disease, including moderate to severe illness (1-3). In addition clinical trials, real-world assessments vaccine effectiveness are critical guiding policy building confidence, particularly among populations at higher risk more from COVID-19, older adults. To determine three...
Adults aged ≥65 years remain at elevated risk for severe COVID-19 disease and have higher COVID-19-associated hospitalization rates compared with those in younger age groups. Data from the COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) were analyzed to estimate during January-August 2023 identify demographic clinical characteristics of hospitalized patients January-June 2023. Among adults years, more than doubled, 6.8 per 100,000 week ending July 15 16.4 August 26,...
(See the editorial commentary by Walsh, on pages 1–3.) Background. Statins may have anti-inflammatory and immunomodulatory effects that could reduce risk of mortality from influenza virus infections. Methods. The Centers for Disease Control Prevention's Emerging Infections Program conducts active surveillance persons hospitalized with laboratory-confirmed in 59 counties 10 states. We analyzed data adults during 2007–2008 season to evaluate association between receiving statins...
Despite ongoing food safety measures in the United States, foodborne illness continues to be a substantial health burden. The 10 U.S. sites of Foodborne Diseases Active Surveillance Network (FoodNet)* monitor cases laboratory-diagnosed infections caused by nine pathogens transmitted commonly through food. This report summarizes preliminary 2017 data and describes changes incidence since 2006. In 2017, FoodNet reported 24,484 infections, 5,677 hospitalizations, 122 deaths. Compared with...
To evaluate progress toward prevention of enteric and foodborne illnesses in the United States, Foodborne Diseases Active Surveillance Network (FoodNet) monitors incidence laboratory-confirmed infections caused by nine pathogens transmitted commonly through food 10 U.S. sites. This report summarizes preliminary 2015 data describes trends since 2012. In 2015, FoodNet reported 20,107 confirmed cases (defined as culture-confirmed bacterial parasitic infections), 4,531 hospitalizations, 77...
Health care personnel (HCP) can be exposed to SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), both within and outside workplace, increasing their risk for infection. Among 6,760 adults hospitalized during March 1-May 31, 2020, whom HCP status was determined by COVID-19-Associated Hospitalization Surveillance Network (COVID-NET), 5.9% were HCP. Nursing-related occupations (36.3%) represented largest proportion of with COVID-19. Median age 49 years, 89.8% had at least...
Background. The 2010–2011 influenza season was dominated by A(H3N2) virus, but A(H1N1) pdm09 (pH1N1) and B viruses cocirculated. This provided an opportunity to explore within-season predictors of severity among hospitalized patients, avoiding biases associated with season-to-season differences in strain virulence, population immunity, healthcare seeking.
Data on the range and severity of influenza-associated complications among children are limited. We describe frequency in hospitalized aged <18 years with seasonal influenza (during 2003-2009) 2009 pandemic A(H1N1) 2009-2010).Population-based surveillance for laboratory-confirmed hospitalizations was conducted 5.3 million 10 states. Complications were identified by International Classification Diseases, Ninth Revision (ICD-9) codes medical records.During 2003-2010, 7293 identified, whom 6769...
COVID-19 adolescent hospitalization rates peaked at 2.1 per 100,000 in early January 2021, declined to 0.6 mid-March, and rose 1.3 April. Among hospitalized adolescents, nearly one-third required intensive care unit admission 5% invasive mechanical ventilation, but no associated deaths occurred.
Persons with influenza can develop complications that result in hospitalization and death. These are most commonly respiratory related, but cardiovascular or neurologic exacerbations of underlying chronic medical conditions may also occur. Patterns observed during pandemics differ from typical seasons, characterizing variations influenza-related provide a better understanding the impact guide appropriate clinical management planning for future.Using population-based surveillance system, we...
In mid-June 2021, B.1.671.2 (Delta) became the predominant variant of SARS-CoV-2, virus that causes COVID-19, circulating in United States. As July Delta was responsible for nearly all new SARS-CoV-2 infections States.* The is more transmissible than previously variants (1); however, whether it severe disease adults has been uncertain. Data from CDC COVID-19-Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system COVID-19-associated...
<h3>Importance</h3> Racial and ethnic minority groups, such as Black, Hispanic, American Indian or Alaska Native, Asian Pacific Islander persons, often experience higher rates of severe influenza disease. <h3>Objective</h3> To describe influenza-associated hospitalization, intensive care unit (ICU) admission, in-hospital death by race ethnicity over 10 seasons. <h3>Design, Setting, Participants</h3> This cross-sectional study used data from the Influenza-Associated Hospitalization...