- Environmental Toxicology and Ecotoxicology
- Aquaculture disease management and microbiota
- Aquatic Ecosystems and Phytoplankton Dynamics
- Aquaculture Nutrition and Growth
- Pesticide and Herbicide Environmental Studies
- Pesticide Exposure and Toxicity
- Zebrafish Biomedical Research Applications
- Melamine detection and toxicity
- Heavy Metal Exposure and Toxicity
- Reproductive biology and impacts on aquatic species
- Soil and Water Nutrient Dynamics
- Iron Metabolism and Disorders
- Trace Elements in Health
- Pharmaceutical and Antibiotic Environmental Impacts
- Soil erosion and sediment transport
- Electrochemical Analysis and Applications
- S100 Proteins and Annexins
- Mercury impact and mitigation studies
- Physiological and biochemical adaptations
- MicroRNA in disease regulation
- Retinoids in leukemia and cellular processes
- Drug Transport and Resistance Mechanisms
- Toxic Organic Pollutants Impact
- Mathematical and Theoretical Epidemiology and Ecology Models
- Mesenchymal stem cell research
Henan Normal University
2019-2025
Trichlorfon is an organophosphorus pesticide widely used in aquaculture and has potential neurotoxicity, but the underlying mechanism remains unclear. In present study, zebrafish embryos were exposed to trichlorfon at concentrations (0, 0.1, 2 5 mg/L) from 144 h post fertilization. exposure reduced survival rate, hatching heartbeat body length increased malformation rate of larvae. The locomotor activity larvae was significantly reduced. results molecular docking revealed that could bind...
Water eutrophication leads to the frequent occurrence of cyanobacterial blooms, which pose a serious threat health and survival fish, top consumer in freshwater ecosystems. The hepatotoxicity induced by microcystin-LR (MC-LR) has been well studied; however, its impact on intestinal flora gut-liver axis rarely reported. This study aimed investigate harmful effects acute oral (303.89 µg/kg.bw) intraperitoneal (i.p., 101.3 exposure MC-LR intestine liver common carp. results showed that...
Previous studies have indicated that the harmful heavy metal lead (Pb) contamination in aquatic systems has caused intelligence development disorders and nervous system function abnormalities juveniles due to increased permeability of blood-brain barrier. Ionic liquids (ILs) are considered "green" organic solvents can replace traditional solvents. Studies found presence ILs soil water chemical applications or unintentional leakage. Therefore, what would happen if Pb interacted with a body...
A subacute toxicity test of 52.077 and 104.154 mg/L glyphosate-based herbicide (GBH) on common carp for 7 days was conducted. The results qPCR reveled that GBH treatment generally promoted the HSP70, HSC70, HSP90 levels in fish liver, kidney, spleen, intestine, suggesting induction HSPs might be associated with GBH. Further research revealed exposure remarkably expressions IL-1β, IL-6, IL-8, IFN-γ, TNF-α at mRNA level altered protein IL-10 TGF-β, inhibited T-AOC activity, but increased MDA...
Chlorpyrifos (CPF) and glyphosate (GLY) are the most widely used organophosphate insecticide herbicide worldwide, respectively; co-occurrence of CPF GLY in aquatic environments occurs where they inevitably have potential hazards to fish. However, mechanisms induce toxicity not been fully explored. To identify adverse impacts on fish, either alone or combination (MIX), (25 μg/L) (3.5 mg/L) were set up according an environmentally relevant concentration expose common carp for 21 days. After...
Previous studies have shown that ILs can induce toxicity in animals, plants, and cells. However, the effect of imidazolium-based on hypothalamus-pituitary-thyroid (HPT) axis fish remains unknown. The present study aimed to evaluate acute [C8mim]Cl embryonic development thyroid-controlled internal secretion system zebrafish by determining thyroid hormone level expression HPT-related genes. results obtained for developmental showed survival rate, heart beats, body length had decreased 96 h...