A5017147299- Spectroscopy Techniques in Biomedical and Chemical Research
- Spectroscopy and Chemometric Analyses
- Optical Coherence Tomography Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Cutaneous Melanoma Detection and Management
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Oral Health Pathology and Treatment
- Optical Imaging and Spectroscopy Techniques
- Colorectal Cancer Treatments and Studies
- Innovations in Medical Education
- Breast Cancer Treatment Studies
- Medical and Pharmaceutic Studies
- Effects of Radiation Exposure
- Cancer Diagnosis and Treatment
- Anorectal Disease Treatments and Outcomes
- Venous Thromboembolism Diagnosis and Management
- AI in cancer detection
- Laser Applications in Dentistry and Medicine
- Neuroblastoma Research and Treatments
- Neurofibromatosis and Schwannoma Cases
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Bee Products Chemical Analysis
- Ultrasound and Hyperthermia Applications
- Intraperitoneal and Appendiceal Malignancies
Samara State Medical University
2009-2024
Samara Regional Clinical Oncology Center
2019-2024
Russian Medical Academy of Continuous Professional Education
2020-2021
In recent years, Raman spectroscopy has been used to study biological tissues. However, the analysis of experimental spectra is still challenging, since most tissue components overlap significantly and it difficult separate individual components. New methods are needed that would allow for decomposition into evaluation their contribution. The aim our work possibilities multivariate curve resolution alternating least squares (MCR-ALS) method skin tissues in vivo. We investigated human...
The paper is devoted to the identification of skin tumors and interpretation their component composition based on multidimensional analysis Raman scattering spectral data dermoscopic images. dataset contains 65 samples malignant melanomas, 107 seborrheic keratoses, 166 nevi. multivariate curve resolution alternating least squares was performed for spectra extract profiles main components composition. obtained biochemical neoplasms were analyzed by gradient boosting method. Dermoscopic image...
In this work the study of optical properties skin tissues using Raman spectroscopy and autofluorescence analysis was performed. The different neoplasms carried out based on spectra stimulated by 785 nm laser. spectral data processed mathematical methods allowed for effective classification malignant benign tumors. proposed diagnostic helped to achieve 82.1-87% differentiation accuracy neoplasms.
In this study, patient data were combined with Raman and autofluorescence spectral parameters for more accurate identification of skin tumors. The tumors classified by projection on latent structures discriminant analysis. importance risk factors was determined using statistical improvement ROC AUCs when factors. Gender, age tumor localization found significant classification malignant versus benign neoplasms, resulting in from 0.610 to 0.818 (p < 0.05). To distinguish melanoma pigmented...
The huge global burden of oncological diseases is growing and measures to counter this complex challenge are high on national health agendas. Russian National Long-Term Oncology Strategy 2030 defines priorities, goals directions in the fight against cancer. Italso contains action plans for more effective prevention, earlier specific diagnosis treatment options. Against backdrop, experts now suggest complement standard oncology strategies by adding Patient Blood Management (PBM). For many...
Early diagnosis of cancer the oral mucosa is still an unsolved problem current Oncology. Despite large number proposed methods precancerosis and cancer, incidence advanced malignant tumors are quite high. The analysis available scientific articles on early has been performed. given literature review studies most common their availability for practical health care Russian Federation.
В данной статье рассматриваются инновационные методы обучения студентов и молодых онкологов, которые внедряются в ВУЗах РФ. Целью является обобщение текущих изменений дидактике России для использования инновационных методов врачей. раскрыты актуальные проблемы внедрения, развития учебном процессе обучения.
Aim – assessment of the effectiveness complex therapy to reduce development early cardiovascular complications. Materials and methods. Information from medical histories outpatient follow-up cards 139 patients with invasive breast cancer was analyzed: in G.V. Bondar Republican Cancer Center 64 (main control groups); as an additional comparison group, study included 75 Samara Regional Clinical Oncology Dispensary. Patients group (33 people) Dispensary (75 received standard (RUSSCO,...
Introduction . Recent decades indicate a significant increase in the incidence of skin cancer. Aim To upgrade specialized device and to improve quality neoplasm diagnostics. Materials methods The study mainly involved method non-invasive differential diagnostics neoplasms. relies upon optical research methods, including Raman spectroscopy, spectroscopic technique. A 10-year study, conducted by Department Oncology, Samara Regional Clinical Oncology Dispensary (SOKOD), included more than 500...
In this in vivo pilot clinical trial, an estimation of NIR spectral features malignant and benign tumors normal skin was carried out. The human tissue spectra simultaneously including Raman spectroscopy autofluorescence signals were registered using the portable spectroscopic equipment with 785 nm excitation laser registration 800-950 area. Spectral data analyzed PLS-DA method extracted relevant information that allow for classification neoplasm type. most important bands found variable...
Relevance. In spite of successes in diagnostic and treatment cancer, malignant neoplasm the esophagus remain an acute problem. Cancer gastroesophageal zone are most prognostically unfavorable disease digestive tract. At time treatment, more than 70% patients with esophageal cancer suffer from grade II – IV dysphagia, which significantly impairs functional state quality life. Dysphagia indicates that lumen is filled a tumor.Purpose. Improve results dysphagia through use fluorescent...
Pulse magnetic fields are widely used in modern technology. We studied the antiaggregation properties of pentoxifylline and aspirin irradiated by a pulsed field at certain parameters: intensity H, frequency f, number pulses n. The impact was carried out both on powdered dissolved drugs solution. aim study is to effect high-intensity PMF antiplatelet activity Evaluation anti-aggregation using method thromboelastography. TEG 5000 apparatus. In analysis thromboelastograms, general coagulation...
This article is dedicated to the issue of quality life patients with colostomy who were operated on for complicated colorectal cancer. Quality after resection obstructive colon has been studied using a scale FACT-C, which consisted sum values FACT-G and special module cancer CRC - concerns. The comparative analysis operation was performed each scales FACT-G, total value FACT-C TOI. study concluded that dynamics totals TOI additional questions show improving colostomy. Colostomy formed in...
We led out the comparative analysis of treatments results in two groups patients with diagnosis colorectal cancer after surgical treatment with progressive process: single Mts in lungs. There were made lungs atypical resections 1 group (42 patients), 2 group (27 patients) - RFA Mts. The greatest percent postoperative complications was in the (9,5%), but this number only 3,7% (р=0,64) RFA. Two-years survival of patients 64%, RFA - 71% (р=0,17). research lifes quality both by Karnovskys...
Skin melanoma is spread inhomogeneously worldwide, particularly in Samara region there are high figures of skin neoplasms sick rate as well—18.6%. Research goal: to develop a new method early non-invasive differential diagnostics neoplasms. Registration Raman spectrum was implemented the distance 3–4 mm, registration from pathologically changed zone subsequently conducted, then healthy zone. The test time for 1 patient no longer than 3–5 min. In range experiments ex vivo were following...