A5101413950- Ziziphus Jujuba Studies and Applications
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Ginseng Biological Effects and Applications
- Metabolomics and Mass Spectrometry Studies
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Ginkgo biloba and Cashew Applications
- Neurological Disease Mechanisms and Treatments
- Polysaccharides and Plant Cell Walls
- Plant and animal studies
- Analytical Chemistry and Chromatography
- Essential Oils and Antimicrobial Activity
- Traditional Chinese Medicine Studies
- Phytochemicals and Antioxidant Activities
- Ginger and Zingiberaceae research
- Food Quality and Safety Studies
- Folate and B Vitamins Research
- Immune cells in cancer
- Chromatography in Natural Products
- Biochemical Analysis and Sensing Techniques
- Medicinal Plant Pharmacodynamics Research
- Polysaccharides Composition and Applications
- Spectroscopy and Chemometric Analyses
- Plant biochemistry and biosynthesis
Nanjing University of Chinese Medicine
2015-2024
University Town of Shenzhen
2015
Tsinghua University
2015
Shanghai Innovative Research Center of Traditional Chinese Medicine
2015
Nanjing University
2009
In this study, a sensitive and rapid method for the simultaneous determination of free amino acids without derivatization using hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry (HILIC-MS/MS) was developed. The performed on an ultra-high-performance (UHPLC) separation system triple-quadrupole (TQ-MS) instrument. Sufficient 23 underivatized achieved Acquity BEH Amide column (2.1 mm × 100 mm, 1.7 μm) in single run 12 min. Then applied analysis 46 batches...
The leaf of Lycium barbarum L. (LLB) has been widely used as a tea, vegetable, and herb in China Southeast Asia for centuries; this is because the hypoglycemic effect it has, but mechanism behind still unclear. In study, type 2 diabetic mellitus (T2DM) rat model, induced by high-fat diet combined with low-dose streptozotocin (STZ) injections, was adopted. biochemical index determined histopathological metabolomics analyses serum urine 16S rDNA sequencing gut microbiota were performed. We...
Ginger powder (GP) is a popular spice in the world. Duo to its nutritional value, GP regarded as an attractive target for adulteration, which not easily detected. In this study, chromaticity analysis and Fourier transform near-infrared (FT-NIR) spectroscopy combined with chemometrics were developed identify quantify of adulterants. The result showed that GPs adulterated cannot be completely distinguished by analysis. While, optimized NIR spectra could accurately distinguish authentic from...
Ginger (Zingiber officinale Roscoe) is one of the most popular spices in world, with its unique odor. Due to health benefits, ginger also widely used as a dietary supplement and herbal medicine. In this study, main flavor components gingers processed by different drying methods including hot air drying, vacuum sun-drying, vacuum-freeze were identified on basis headspace-gas chromatography coupled mass spectrometry (HS-GC-MS) fast gas electronic-nose (fast GC e-nose) techniques. The results...
The fruits of Ziziphus species have been utilized as food well crude drugs for their health benefits in China thousands years. This paper reported a reversed-phase high-performance liquid chromatography (HPLC) method the simultaneous characterization and quantitation 11 triterpenic acids chloroform extracts jujube by using an evaporative light scattering detector (ELSD) electrospray ionization-mass spectrometry (ESI-MS). results showed that contents jujuba var. spinosa were higher than those...
As a traditional Chinese medicine, the root of Astragalus membranaceus var. mongholicus (AMM) or A. (AM) has been widely used in China and other Asian countries for thousands years. Till now, flavonoids, phenolic acids saponins are considered as main active components contributing to their therapeutic effect these plants. In order clarify distribution contents compounds different organs plants, rapid sensitive analytical method simultaneous determination 25 including seven types (i.e....
Salvia miltiorrhiza is a traditional Chinese herbal medicine containing multiple components that contribute to its notable bioactivities. This article investigated the distribution and dynamic changes of chemical constituents in various parts S. from different growth periods. An ultra-high performance liquid chromatography-triple quadrupole mass spectrometer (UPLC-TQ-MS/MS) high-performance chromatography coupled with evaporative light scattering detector (HPLC-ELSD) methods were developed...
Mulberry leaf is one of the commonly used traditional Chinese medicines, has been shown to exert hypoglycemic effects against diabetes. The aim this study investigate and mechanism mulberry flavonoids (MF), polysaccharides (MP) alkaloids (MA) on diabetic its liver kidney injury. db/db mice was adopted results showed that FBG (fasting blood glucose) model group continued increase associated After intervention MP MA, value exhibited most obvious effect. MF have improved effect injury, which...
Present studies have shown that Flos Chrysanthemi has anti-inflammatory and other effects regulates intestinal function, while the chrysanthemum stem leaf as non-medicinal parts of similar chemical components with chrysanthemum, but activity mechanisms are rarely elucidated. Therefore, this study used a DSS-induced zebrafish inflammatory bowel disease model to antioxidant extracts. The results indicate DSS induction leads increased secretion acidic mucin in intestines juvenile fish,...
The fruit of Ziziphus jujuba, named dazao in Chinese, has been utilized as food well crude drugs China for thousands years. To explore the profiles nucleosides and nucleobases this fruit, an ultraperformance liquid chromatograph coupled with a photodiode array detector electrospray ionization−mass spectrometer method (UPLC-DAD-MS) established validated paper. was successfully applied simultaneous characterization quantitation 9 49 samples, which comprised 43 cultivars from 26 cultivation...
Abstract Frankincense and myrrh are highly effective in treatment of inflammatory diseases, but lacking the therapy mechanisms. We undertook this study to evaluate effects on Adjuvant-induced Arthritis (AIA) rats explore underlying mechanisms by analyzing metabolic profiling signaling pathway evaluated expression cytokines, c-jun c-fos corresponding phosphorylation levels. The results stated elevated levels TNFα, PGE 2 , IL-2, NO MDA serum swelling paw AIA were significantly decreased after...