Silvia González-Nieves

ORCID: 0000-0002-4706-6184
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About
Contact & Profiles
Research Areas
  • Lymphatic System and Diseases
  • Nuclear Structure and Function
  • Wnt/β-catenin signaling in development and cancer
  • Epigenetics and DNA Methylation
  • Cancer Cells and Metastasis
  • Body Contouring and Surgery
  • Educational Outcomes and Influences
  • Angiogenesis and VEGF in Cancer
  • Child and Adolescent Psychosocial and Emotional Development
  • E-Learning and Knowledge Management
  • Protein Degradation and Inhibitors
  • Autism Spectrum Disorder Research
  • Health and Lifestyle Studies
  • Public Health and Environmental Issues
  • Alcoholism and Thiamine Deficiency
  • Education and Teacher Training
  • Adipose Tissue and Metabolism
  • Dementia and Cognitive Impairment Research
  • Adipokines, Inflammation, and Metabolic Diseases
  • Amyotrophic Lateral Sclerosis Research
  • Cancer-related gene regulation
  • Educational methodologies and cognitive development
  • Educational Innovations and Technology

Saint Louis University
2024-2025

UCLouvain Saint-Louis Brussels
2024

Universidad de Los Andes
2021-2022

Universidad de Los Andes
2019

Pedagogical and Technological University of Colombia
2016-2018

Colciencias
2016-2017

Consejo Nacional de Ciencia y Tecnología
2016-2017

ABSTRACT Inadequate angiogenesis in obesogenic adipose tissue (AT) has been implicated disrupted adipogenesis and metabolic disorders. Yet, key cellular molecular regulators of AT remain largely unidentified. This study sought to identify the dysregulated elements within Vascular Endothelial Growth Factor (VEGF) Platelet-Derived (PDGF) systems during obesity progression. We employ a mouse model, comprising both male female mice, investigate changes VEGF/PDGF concentration their receptor...

10.1101/2025.02.14.638177 preprint EN public-domain bioRxiv (Cold Spring Harbor Laboratory) 2025-02-16

Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and vessel maintenance. Altered lipid is associated with loss of integrity, which compromises organ function, protective immunity, metabolic health. Thus, understanding how affects LECs for uncovering the mechanisms underlying dysfunction. Protein palmitoylation, lipid-based post-translational modification, has emerged as regulator protein stability, interaction networks. Insulin, master systemic...

10.1016/j.jlr.2025.100775 article EN cc-by Journal of Lipid Research 2025-03-01

Due to its short-term storage and manipulation of information functions, working memory is one the most cognitive components related learning. The objective this literature review present recent evidence relationship possible implications for education. In order understand association in depth, various findings on connection between academic performance are explained detail. addition, increase capacity different studies through training methodologies shown. Finally, practical education discussed.

10.22525/sabcliber.2016v11n2.161176 article EN cc-by-nc-sa Saber ciencia y libertad 2017-07-28

Lipedema is a lipodystrophic disease that typically characterized by marked increase in lower-body subcutaneous adipose tissue purported to have increased inflammation and fibrosis, impaired microvascular/lymphatic circulation be resistant reduction weight loss therapy. However, these outcomes not been adequately studied. We evaluated body composition, insulin sensitivity, metabolic health biology women with obesity lipedema (Obese-LIP) before after moderate (~9%) diet-induced loss. At...

10.2337/db24-0890 article EN Diabetes 2024-12-09

Debido a sus funciones de almacenamiento y manipulación la información en el corto plazo, Memoria Trabajo es uno los componentes cognitivos más relacionados con aprendizaje. El objetivo esta revisión bibliográfica presentar evidencia reciente dicha relación posibles implicaciones para educación. Para entender fondo asociación, se explican detalle diversos hallazgos sobre conexión entre desempeño académico. En adición, muestra del aumento capacidad distintos estudios través diferentes...

10.18041/2382-3240/saber.2016v11n2.554 article ES cc-by-nc-sa Saber ciencia y libertad 2016-07-01

Major Depression is a complex disorder with growing incidence worldwide and multiple variables have been associated its etiology. Nonetheless, diagnosis continually changing the need to understand it from multidimensional perspective clear. The purpose of this study was identify risk factors for depression in case-control 100 depressive inpatients 87 healthy controls. A multivariate logistic regression analysis performed including psychosocial factors, cognitive maladaptive schema domains,...

10.3389/fpsyt.2021.768680 article EN cc-by Frontiers in Psychiatry 2021-12-14

ABSTRACT Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and maintenance. Altered lipid is associated with loss of vessel integrity, which compromises organ function, protective immunity, metabolic health. However, the LEC function not well understood. Insulin key regulator protein palmitoylation, reversible post-translational modification by palmitate that affects stability, trafficking, protein-protein, protein-membrane interactions. Human LECs are...

10.1101/2024.05.06.592341 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-05-07

<p dir="ltr">Lipedema is a lipodystrophic disease that typically characterized by marked increase in lower-body subcutaneous adipose tissue purported to have increased inflammation and fibrosis, impaired microvascular/lymphatic circulation be resistant reduction weight loss therapy. However, these outcomes not been adequately studied. We evaluated body composition, insulin sensitivity, metabolic health biology women with obesity lipedema (Obese-LIP) before after moderate (~9%)...

10.2337/figshare.27960645.v1 preprint EN cc-by-nc-sa 2024-12-09

<p dir="ltr">Lipedema is a lipodystrophic disease that typically characterized by marked increase in lower-body subcutaneous adipose tissue purported to have increased inflammation and fibrosis, impaired microvascular/lymphatic circulation be resistant reduction weight loss therapy. However, these outcomes not been adequately studied. We evaluated body composition, insulin sensitivity, metabolic health biology women with obesity lipedema (Obese-LIP) before after moderate (~9%)...

10.2337/figshare.27960645 preprint EN cc-by-nc-sa 2024-12-09

Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative disease of presenile onset. A better characterization disorders has been sought by using tools such as genome-wide association studies (GWAS), where associations between single nucleotide polymorphisms (SNPs) and cognitive profiles could constitute predictive biomarkers for these diseases. However, in FTD, genotypes phenotypes are yet to be explored. Here, we evaluate possible relationship genetic variants some functions an...

10.3389/fneur.2022.675301 article EN cc-by Frontiers in Neurology 2022-08-22
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