A5001123710- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Oral health in cancer treatment
- Cancer Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Effects of Radiation Exposure
- Advanced X-ray and CT Imaging
- Radiation Effects and Dosimetry
- Skin Protection and Aging
- Ultrasound and Hyperthermia Applications
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Medical Imaging and Analysis
- Ultrasound in Clinical Applications
- RNA modifications and cancer
- Advancements in Battery Materials
- Cutaneous lymphoproliferative disorders research
- Peripheral Artery Disease Management
- Cancer Cells and Metastasis
- Radiopharmaceutical Chemistry and Applications
Sir Charles Gairdner Hospital
2017-2025
The University of Western Australia
2024
Odense University Hospital
2024
Centre for Cancer Biology
2024
Princess Margaret Hospital for Children
2024
Perth Children's Hospital
2024
Curtin University
2022-2024
National Cancer Centre Japan
2022
WA Country Health Service
2022
Townsville Hospital
2007-2014
Abstract Objective . Clinical implementation of synthetic CT (sCT) from cone-beam (CBCT) for adaptive radiotherapy necessitates a high degree anatomical integrity, Hounsfield unit (HU) accuracy, and image quality. To achieve these goals, vision-transformer anatomically sensitive loss functions are described. Better quantification quality is achieved using the alignment-invariant Fréchet inception distance (FID), uncertainty estimation sCT risk prediction implemented in scalable plug-and-play...
Aim Chronic radiation injuries, although uncommon, are associated with poor quality of life in oncology patients. The present study assesses the efficacy and safety hyperbaric oxygen therapy management chronic radiation-induced tissue injuries. Methods A retrospective analysis was performed 276 consecutive patients treated for injuries at Hyperbaric Medicine Unit, Townsville, Queensland, between March 1995 2008. Of these patients, 189 (68%) had complete follow-up data were assessed. Results...
Pigment epithelium-derived factor (PEDF) is a natural immunomodulator, anti-inflammatory, anti-angiogenic, anti-tumour growth and anti-metastasis factor, which can enhance tumour response to PEDF but also conversely have pro-cancerous effects. Inflammation major cause of cancer, it has been proven that anti-inflammatory properties. PEDF’s functional activity be investigated through measuring metastatic metabolic biomarkers will discussed in this review.
In this retrospective analysis, we describe the efficacy and tolerability of weekly cisplatin 40 mg/m(2) used in concurrent chemoradiation head neck cancer at Townsville Cancer Centre.Review medical records patients who received radical chemoradiotherapy for Centre from 2003 to 2009.In all 102 were analysed, 62 whom had definitive remainder adjuvant chemoradiotherapy. Median follow up was 20.1 months (range 5-86 months). Overall 68.6% 5 weeks or more planned chemotherapy. Radiotherapy...
Abstract Artificial Intelligence (AI) based auto-segmentation has demonstrated numerous benefits to clinical radiotherapy workflows. However, the rapidly changing regulatory, research, and market environment presents challenges around selecting evaluating most suitable solution. To support adoption of AI systems, Selection Criteria recommendations were developed enable a holistic evaluation vendors, considering not only raw performance but associated risks uniquely related deployment AI....
Abstract Radiotherapy is an essential component of cancer treatment, but healthy tissues can be exposed to out-of-field doses, potentially causing adverse effects and secondary cancers. This study investigates peripheral doses outside the electron beam applicator in Elekta Versa HD linear accelerator. Peripheral were measured using 6, 9, 12 MeV beams at their respective maximum dose depths while maintaining a 100 cm source-to-surface distance. Measurements employed EBT3 films within Plastic...
Abstract Purpose A fundamental parameter to evaluate the beam delivery precision and stability on a clinical linear accelerator (linac) is focal spot position (FSP) measured relative collimator axis of radiation head. The aims this work were comprehensive data FSP acquired linacs in use establish ability alternative phantoms detect effects patient plan related FSP. Methods measurements conducted using rigid phantom holding two ball-bearings at different distances from source. Images these...
Abstract Over the past decade, our institution delivered conventional total body irradiation (TBI) using Elekta's Monaco treatment planning system (TPS) with an extended SSD field arrangement and 18 megavoltage (MV) energy lateral fields. In 2020, there was a transition to Eclipse™ Truebeam® linear accelerators 6 MV 10 energies. These changes meant that essential components of existing technique were unavailable for clinical use new approach required ensure continuation service. The aim...
Abstract A fundamental parameter to evaluate the beam delivery precision and stability on a clinical linear accelerator (linac) is focal spot position (FSP) measured relative collimator axis of radiation head. The aims this work were comprehensive data FSP acquired linacs in use establish ability alternative phantoms detect effects patient plan related FSP. measurements conducted using rigid phantom holding two ball-bearings at different distances from source. Images these electronic portal...
Abstract Background Radiotherapy is an essential component of cancer treatment, but healthy tissues can be exposed to out-of-field doses, potentially causing adverse effects and secondary cancers. This study investigates peripheral doses outside the electron beam applicator in Elekta Versa HD linear accelerator. Methods Peripheral were measured using 6, 9, 12 MeV beams at their respective maximum dose depths while maintaining a 100 cm source-to-surface distance. Measurements employed EBT3...
Abstract Purpose Total skin electron therapy (TSET) is a complex radiotherapy technique, posing challenges in commissioning and quality assurance (QA), especially due to significant variability patient body shapes. Previous studies have correlated dose with factors such as obesity index, height, gender. However, current treatment planning systems cannot simulate TSET plans, necessitating heavy reliance on QA methods using standardized anthropomorphic phantoms in‐vivo dosimetry. Given the...
Introduction In 2020, the Australian Medical Services Advisory Committee (MSAC) recommended new proton beam therapy (PBT) item numbers be added to Medicare Benefits Schedule. During MSAC 1638 application process, recognised uncertainties inherent in cost-utility modelling of PBT. To address these uncertainties, proposed establishment a national registry with intention gather evidence validate claim PBT’s superior toxicity outcomes and cost-effectiveness compared conventional photon radiation...