A5063613818- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Ion channel regulation and function
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Cardiac tumors and thrombi
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Heart rate and cardiovascular health
- Cardiovascular Disease and Adiposity
- Cardiomyopathy and Myosin Studies
- Pericarditis and Cardiac Tamponade
- Receptor Mechanisms and Signaling
- Atherosclerosis and Cardiovascular Diseases
- Neuroscience and Neuropharmacology Research
- ECG Monitoring and Analysis
- Paraoxonase enzyme and polymorphisms
Hiroshima City Asa Citizens Hospital
2016-2023
Citizens Specialty Hospitals
2019-2023
Japanese Circulation Society
2023
Society for Vascular Surgery
2023
Hiroshima University Hospital
2009-2019
National Yang Ming Chiao Tung University
2009-2017
Taipei Veterans General Hospital
2009-2017
National Science and Technology Council
2017
Hiroshima University
2007-2017
Hiroshima Prefectural Hospital
2012-2017
Background— Catheter ablation of atrial fibrillation (AF) became an effective therapy for patients with drug-refractory AF, and the indications have broadened to include nonparoxysmal AF patients. However, data about long-term effectiveness in are lacking. The aim present study was investigate outcomes catheter AF. Methods Results— A total 88 who received a stepwise (isolation pulmonary veins plus substrate modification) from 2006 2008 were enrolled. Freedom recurrence defined as absence...
<h3>Objective</h3> The atrial electromechanical (PA–PDI) interval was reported to be a useful predictor of new-onset fibrillation (AF) and the occurrence AF after coronary artery bypass surgery. aim this study investigate associations with substrate properties outcome catheter ablation in paroxysmal patients. <h3>Methods</h3> 132 patients who had received were enrolled. determined as time from initiation P-wave deflection peak mitral inflow A-wave on pulse-wave Doppler imaging. left voltage...
Background: Renal dysfunction was reported to be associated with a higher recurrence rate after electric cardioversion of atrial fibrillation (AF). The aim this study investigate the associations between renal function, substrate properties and outcome catheter ablation in paroxysmal AF patients. Methods Results: A total 232 patients that underwent were enrolled study. estimated glomerular filtration (GFR) calculated using Cockcroft-Gaut equation normalized by body surface area, divided into...
Background— Heat shock protein (HSP) 27 is related to the pathogenesis of AF. However, clinical relationship between HSP27 and AF unclear. The present study was conducted determine atrial fibrillation (AF). Methods Results— A case-control (AF, n=114; control, n=100). Serum (HSP27S) levels were measured by ELISA, its correlations with electrophysiological characteristics catheter ablation outcomes investigated. patients had a larger left diameter (LAD), waist circumference, body mass index,...
The HATCH score (hypertension <1 point>, age >75 years stroke or transient ischemic attack <2 points>, chronic obstructive pulmonary disease and heart failure points>) was reported to be useful for predicting the progression of atrial fibrillation (AF) from paroxysmal persistent permanent AF patients who participated in Euro Heart Survey. goal current study investigate whether a scheme new-onset AF. Furthermore, we aimed use scoring system estimate individual risk developing with different...
Previous studies have indicated that atrial fibrillation (AF) in patients over the age of 60 at diagnosis is a risk factor for substantial increase cardiovascular events. However, information about impact on substrate and clinical outcome after catheter ablation AF limited.This study included 350 (53 ± 12 years, 254 males) who underwent circumferential pulmonary vein isolation (CPVI) AF, guided by NavX mapping system. The subjects were divided into three groups according to their age, as...
Ivabradine is a novel heart rate decreasing agent with selective and specific antagonist effects on the pacemaker current (I(f)). The aim of this study was to investigate pharmacological ivabradine pulmonary vein (PV) cardiomyocytes.Whole-cell patch-clamp techniques indo-1 fluorimetric ratio technique were used characteristics I(f) intracellular calcium (Ca(2+)(i)) in single isolated rabbit PV cardiomyocytes activity before after an administration (0.3, 3, 10, 30 μM). μM) concentration...
Additional ablation in the pulmonary vein (PV) carina region is sometimes required to achieve electrical isolation following circumferential (PVI).This study investigated procedural predictors for requirement of additional complete with PVI. Methods and resultsEighty patients drug-refractory paroxysmal AF underwent PVI.After first round PVI, we placed circular catheters inside veins identify residual PV potentials, also performed electroanatomic mapping observe earliest activation sites...
Gender Differences in Patients With AVNRT. Introduction: The detailed electrophysiological characteristics of the gender differences associated with atrioventricular nodal reentrant tachycardia (AVNRT) have not been clarified. This study investigated gender‐related a large series patients undergoing radiofrequency catheter ablation. Methods and Results: A total 2,088 consecutive AVNRT (men/women 869/1,219) who underwent ablation were enrolled this study. We evaluated their characteristics....
Macroreentrant and Focal Atrial Tachycardias. Background: tachycardias (ATs) are commonly observed following catheter ablation of atrial fibrillation (AF). The aim this study was to identify ECG characteristics that differentiate focal from macroreentrant ATs after circumferential pulmonary vein isolation (CPVI). Methods Results: One hundred twenty occurred CPVI were mapped using a 3-dimensional mapping system in 87 patients with AF. Further performed eliminate the ATs. surface ECGs 68 41...
Unexplained cardiac arrest (UCA) with documented ventricular fibrillation (VF) is a major cause of sudden death. Abnormal sympathetic innervations have been shown to be trigger fibrillation. Further, adequate expression SEMA3A was reported critical for normal patterning innervation. We investigated the relevance semaphorin 3A (SEMA3A) gene located at chromosome 5 in etiology UCA. Eighty-three Japanese patients diagnosed UCA and 2,958 healthy controls from two different geographic regions...
Early restoration of sinus rhythm following ablation atrial fibrillation (AF) facilitates reverse remodeling and improves the long-term outcome. The purpose this study was to determine predictors outcome in patients with very early AF recurrences (< 2 days).Ablation performed 339 consecutive (paroxysmal = 262). Biatrial voltage mapped during rhythm. If recurrent occurred within days ablation, electrical cardioversion restore Very 39 (15%) paroxysmal 26 (34%) nonparoxysmal AF. Patients...
Nonpulmonary vein (PV) ectopy initiating atrial fibrillation (AF)/atrial tachycardia (AT) is not uncommon in patients with AF. The relationship of complex fractionated electrograms (CFAEs) and non-PV AF/AT has been assessed. We aimed to characterize the CFAEs AF/AT.Twenty-three (age 53 +/- 11 y/o, 19 males) who underwent a stepwise AF ablation coexisting PV or AT were included. CFAE mapping was applied before after isolation both atria by using real-time NavX electroanatomic system. A...