A5060656048- Pesticide Exposure and Toxicity
- Heat shock proteins research
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Cardiovascular Disease and Adiposity
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Adipokines, Inflammation, and Metabolic Diseases
- Epigenetics and DNA Methylation
- Pancreatic function and diabetes
- Carcinogens and Genotoxicity Assessment
- Biomarkers in Disease Mechanisms
- Antioxidant Activity and Oxidative Stress
- SARS-CoV-2 and COVID-19 Research
- Exercise and Physiological Responses
- Circular RNAs in diseases
- Environmental Toxicology and Ecotoxicology
- Lipoproteins and Cardiovascular Health
- Meat and Animal Product Quality
- CRISPR and Genetic Engineering
- Pesticide and Herbicide Environmental Studies
- Thermoregulation and physiological responses
- Systemic Lupus Erythematosus Research
- Asthma and respiratory diseases
- Chemotherapy-induced organ toxicity mitigation
Kerman University of Medical Sciences
2018-2025
Tehran University of Medical Sciences
2014-2023
Mashhad University of Medical Sciences
2010-2012
Abstract Cholestatic liver disease is recognized by extreme collagen formation and deposition, which mediated free radicals. The aim of the current study was to investigate probable hepatoprotective effects hydroalcoholic extract watercress (WC) against oxidative stress injury in bile duct ligation (BDL)‐ induced cholestatic rats. A total 32 male Wistar rats were divided into four groups; sham control (SC), BDL, SC + WC BDL WC. WC‐treated received daily 500 mg/kg/day for 10 days. Biochemical...
Asthma is an inflammatory disease of the airways. We assessed anti-inflammatory and antioxidative impacts quercetin, a plant derivative, on oxidative indices in lung tissue serum rats with asthma.Asth ma was induced by ovalbumin. Rats were divided into 4 groups: control, asthma+vehicle (Receieved normal saline), asthma+dexamethasone, asthma+quercetin. After asthma induction, quercetin (50 mg/kg) dexamethasone (2.5 injected intraperitoneally once daily for 1 week. On day 50, histopathology...
Asthma is known as a disease that causes breathing problems in children and adults also associated with chronic inflammation oxidative stress of the airways. Nasturtium officinale (NO) possesses wide range pharmacological properties, particularly anti-inflammation antioxidant potentials. Thus, this study for first time was aimed to investigate anti-inflammatory antioxidative activities NO extract (NOE) an ovalbumin-induced rat model asthma.Forty-four male Wistar rats were sensitized...
Coronary artery bypass graft surgery is one of the most frequently performed surgeries worldwide. induces an inflammatory response. Interleukin-8 a pro-inflammatory cytokine that plays role in pathogenesis cardiovascular diseases. C1q/TNF-related protein-12 implicated mitigating inflammation and cardiomyocyte damage. This study aimed to compare interleukin-8 levels before 45 days after coronary surgery. A total 43 patients who underwent were studied. Serum concentrations evaluated using...
Antibody titers to several heat shock proteins (anti-Hsps) have been reported be associated with the severity and progression of cardiovascular disease. However, there are little data regarding anti-Hsp27 in patients coronary artery disease (CAD). A total 400 suspected CAD were recruited. Based on results angiography, these classified into CAD(+) (n = 300) CAD(-) 100) groups defined as ≥50% <50% stenosis any major artery, respectively. Eighty-three healthy subjects also recruited control...
Abstract Chemical pesticides or insecticides with complex structures are highly abundant in the biosphere and have inevitable side effects on farmland, natural resources, human health. Deltamethrin is most popular widely used pesticide that disrupts cellular calcium channels. In present study, isolated strains of bacteria were examined to determine ones capable degrading deltamethrin. Different species evaluated terms capability degrade It important note Streptomyces rimosus was able up 200...
Parkinson's disease (PD) is a complex disorder that arises from genetic and environmental factors. The current investigation endeavors to investigate the role of exposure organochlorine (OCPs) organophosphate pesticides (OPPs), recognized as main elements, in genesis PD. In this case-control study, 29 PD patients 51 healthy subjects were involved. Gas chromatography was performed measure serum levels chemicals (2,4-DDT, 4,4-DDT, 2,4-DDE, 4,4-DDE, α-HCH, β-HCH, γ-HCH). Furthermore,...
It has been suggested that antioxidized low-density lipoprotein (anti-oxLDL) antibodies play a role in the pathogenesis of atherosclerosis. The aim this study was to measure serum ox-LDL IgG levels 31 patients with angiographically defined coronary artery disease (CAD) (≥50% stenosis at least one major artery; CAD + group) and compare these those 32 subjects <50% (CAD − 24 healthy age- sex-matched controls using ELISA. We did not find any significant difference between , control groups...