A5018189919- biodegradable polymer synthesis and properties
- Nanoplatforms for cancer theranostics
- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Polymer crystallization and properties
- Carbon dioxide utilization in catalysis
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Skin Protection and Aging
- Extracellular vesicles in disease
- Advancements in Transdermal Drug Delivery
- Laser Applications in Dentistry and Medicine
- Supercapacitor Materials and Fabrication
- Organometallic Complex Synthesis and Catalysis
- Photodynamic Therapy Research Studies
- Advancements in Battery Materials
- Natural Fiber Reinforced Composites
- Cellular Mechanics and Interactions
- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
- MXene and MAX Phase Materials
- Silicone and Siloxane Chemistry
- Magnetism in coordination complexes
- Microplastics and Plastic Pollution
- Lanthanide and Transition Metal Complexes
Sichuan University
2011-2025
State Key Laboratory of Oral Diseases
2020-2024
Quanzhou Normal University
2024
Lanzhou Jiaotong University
2024
Peking University
2024
Beijing National Laboratory for Molecular Sciences
2024
West China Hospital of Sichuan University
2022
Cornell University
2021
University of California, Davis
2021
Case Western Reserve University
2021
Bio-plastics have gained tremendous attention, due to the increasing environmental pressure on global warming and plastic pollution. Among them, poly (lactic acid) (PLA) is both bio-based bio-degradable, which has been widely used in many disposable packaging applications. The market for PLA demand doubles every 3–4 years, as estimated by Jem's law. Compared traditional petroleum-based plastics, more expensive usually less mechanical physical properties. recent compounding efforts...
Unique properties of PGA, and its modifications applications.
Conventional biomaterial-mediated osteosarcoma therapy mainly focuses on its antitumor effect yet often fails to overcome the problem of post-treatment bone tissue defect repair. Simultaneously, minimally invasive drug delivery methods are becoming spotlights for normal preservation. Herein, an injectable curcumin-microsphere/IR820 coloaded hybrid methylcellulose hydrogel (Cur-MP/IR820 gel) platform was designed and regeneration. In vitro, K7M2wt cells were eradicated by hyperthermia...
Due to its high crystallinity, tailored compostability, and superior barrier performance, poly(glycolic acid) (PGA) has great potential as a substitute for current single-use plastics used in food packaging applications with lower carbon footprint. However, susceptibility hydrolysis mechanical brittleness hinders direct suitability packaging. In this work, we circumvent limitation by first blending PGA thermoplastic polyester, poly(butylene adipate-co-terephthalate) (PBAT), glycidyl...
Abstract Tumor killing and wound healing are two complementary influential processes during the treatment of melanoma. Herein, a two-layered microneedle platform was developed with bifunctional effect chemo-photothermal synergistic melanoma therapy skin regeneration. The composed embeddable curcumin nanodrugs/new Indocyanine Green/hyaluronic acid (Cur NDs/IR820/HA) microneedles sodium alginate/gelatin/hyaluronic (SA/Ge/HA) supporting backing layer prepared through two-step casting process....
Platelet-rich fibrin (PRF) is an autologous growth factor carrier that promotes bone tissue regeneration, but its effectiveness restrained by poor storage capabilities, uncontrollable concentration of factors, unstable shape, etc. Herein, we developed a photocrosslinkable composite hydrogel incorporating lyophilized PRF exudate (LPRFe) into the carboxymethyl chitosan methacryloyl (CMCSMA)/gelatin (GelMA) to effectively solve dilemma PRF. The possessed suitable physical properties and...
Abstract Among commercial biodegradable polyesters, poly(glycolic acid) (PGA) has been rarely investigated for packaging applications, despite its unique advantages such as 100% compostability, high degree of crystallinity, thermal stability and gas barrier properties. The application PGA limited by mechanical brittleness, moisture sensitivity, melting temperature (~240°C), restricting processing applications film packaging. In this study, was modified blending with poly (butylene...
Neutral inverse-sandwich rare-earth metal complexes of the parent benzene tetraanion with an [M 3+ –(C 6 H ) 4− –M ] core electronic structure were synthesized and characterized. They behave as a four-electron reductant to reduce unsaturated substrates.
As one of the leading threats for health among women worldwide, breast cancer has high morbidity and mortality. Surgical resection is major clinical intervention primary tumor, nevertheless local recurrence risk tissue defect remain two main dilemmas, seriously affecting survival quality life patients.We developed a thermoresponsive injectable hybrid hydrogel platform (IR820/Mgel) by integration co-loaded porous microspheres (MPs) IR820 preventing postoperative via photothermal therapy...
A near-infrared light-responsive hybrid hydrogel was injected in the tumor site. IR820 could not only produce local heat for photothermal therapy, but also generate singlet oxygen to induce degradation of MSNs controllable drug release.
Abstract This study investigated the effects of urea/ethanolamine mixture (UE) on crystallinity, thermal, and mechanical properties poly(vinyl alcohol) (PVA) films. PVA films were prepared from solutions containing PVA, urea, ethanolamine, water by casting evaporating at 50°C for 12 h. The plasticization efficiency UE was compared with that glycerol (GL), conventional plasticizer PVA. plasticized GL, abbreviated to UE‐plasticized film GL‐plasticized film, respectively, Fourier‐transform...
Post-extraction alveolar bone atrophy greatly hinders the subsequent orthodontic tooth movement (OTM) or implant placement. In this study, we synthesized biodegradable bifunctional bioactive calcium phosphorus nanoflowers (NFs) loaded with abaloparatide (ABL), namely ABL@NFs, to achieve spatiotemporal management for regeneration. The NFs exhibited a porous hierarchical structure, high drug encapsulation efficacy, and desirable biocompatibility. ABL was initially released recruit stem cells,...