A5028694539- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Organometallic Complex Synthesis and Catalysis
- Metal complexes synthesis and properties
- Catalytic Cross-Coupling Reactions
- Crystallography and molecular interactions
- Catalytic Alkyne Reactions
- Magnetism in coordination complexes
- Catalytic C–H Functionalization Methods
- Coordination Chemistry and Organometallics
- Organometallic Compounds Synthesis and Characterization
- Asymmetric Hydrogenation and Catalysis
- Cyclopropane Reaction Mechanisms
- Synthesis and characterization of novel inorganic/organometallic compounds
- Synthetic Organic Chemistry Methods
- Inorganic and Organometallic Chemistry
- Fluorine in Organic Chemistry
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Organic and Molecular Conductors Research
- Oxidative Organic Chemistry Reactions
- Ferrocene Chemistry and Applications
- Phosphorus compounds and reactions
- Synthesis and Reactivity of Heterocycles
- Crystal structures of chemical compounds
- Chemical Synthesis and Reactions
Universidad de Murcia
2014-2025
Universitat Politècnica de València
2024
Rede de Química e Tecnologia
2014-2015
Centro Médico Sanitas Murcia
2015
Hospital Reina Sofía de Murcia
2015
Central University of Venezuela
2012
Instituto de Investigaciones Químicas
2009
Technische Universität Braunschweig
1990-2008
Universidad Autónoma de Madrid
1993
Universidad de Zaragoza
1975-1981
The reaction between [Pd(C6H3NNR-2, X-5)Cl]2 and phosphines gives [Pd(C6H3NNTo-2,Me-5)Cl(L)] [To = C6H4Me-4, L PEt3 (1a), PPh2Me (1b)] or trans-[Pd(C6H3N2To-2,Me-5)ClL2] (L (2a), (2b), L2 bis(diphenylphosphino)methane dppm (2c)) trans-[Pd(C6H3N2X-2, R-5)Cl(μ-dppm)]2 (X Me, R To (3a); X H, Ph (3b)), depending on the molar ratio of reagents. Tl(OTf) (OTf O3SCF3), AgClO4, AgSbF6 react with 1a,b, 2a, 2c, 3a to give, variously, [Pd(C6H3NNTo-2,Me-5)(Y)(L)] PEt3, Y TfO (4a); PPh2Me, (4b), ClO4...
Insertion of CO into 2-aminophenylpalladium complexes leads to 2-aminobenzoylpalladium derivatives. When these compounds are forced coordinate a carbon donor and phosphane ligand in the trans position, C−P coupling process or an insertion oxygen occurs (see scheme). In this case, dinuclear palladium complex containing bridging anthranilato is isolated.
Reactions of AuCl(tht) (tht = tetrahydrothiophene) with various ylides in equimolar amounts give the complexes [AuCl(ylide)]Xn (n 0, ylide C(PPh3)2 (1a), 4-MeC6H4SO2CHPPh3 (1b); n 1, X TfO, [HC(PPh3)2]+ (2)) and [(AuCl)2{μ-C(PPh3)2}] (3) when using a 2:1 molar ratio. The complex 1a reacts (i) Tl(acac) to [Au(acac){C(PPh3)2}] (4) (ii) terminal alkynes (with or without added Et3N) [HC(PPh3)2][Au(C⋮CC6H4R-4)Cl] (R H (5a), CN (5b), OMe (5c), NO2 (5d)) instead desired [Au(C⋮CC6H4R-4){C{PPh3}2}]....
By the refluxing of an acetonitrile solution [Pd(OAc)2]3 and primary amines 4-XC6H4CH2NH2 (F, Cl, NO2, OMe), 3,5-X2C6H3CH2NH2 (X = or PhCH2CH2NH2 (Pd:amine 1:1) subsequent addition excess NaBr, corresponding orthometalated complexes [Pd{C6H3(CH2NH2)-2,X-5}(μ-Br)]2, [Pd{C6H3(CH2NH2)-2,(OMe)2-4,6}(μ-Br)]2, [Pd{C6H3(CH2NH2)-2}(μ-Br)]2 are obtained. Alternatively, hydrochloride F, NO2) can also be used to prepare [Pd{C6H3(CH2NH2)-2,X-5}(μ-Cl)]2 complexes. These results show that benzylamines...
IV gewinnt: Der Komplex 1⋅OAc (siehe Schema) reagiert mit 2-Iodbenzoesäure zu den stabilen Palladium(IV)-Komplexen 2 a,b. Diese sind Präkatalysatoren für die Orthovinylierung von CH2CHCO2Me und AgClO4 bei Raumtemperatur. Die Reaktion wird durch einen Überschuss an Hg nicht gestoppt liefert kein Dibenzyl in Gegenwart Benzylchlorid, woraus folgern ist, das weder Palladium-Nanopartikel noch ein Palladium(0)-Komplex beteiligt sind. Detailed facts of importance to specialist readers are...
We have studied the reactivity of complexes [Pd(C6H4X-2)Br(bpy)] (bpy = 2,2'-bipyridine; X C(O)Me (1a), CN (1b), CHO (1c)), [Pd{C6H4CHCH2-2}(PPh3)(bpy)](TfO) (TfO CF3SO3; 2d), trans-[Pd(C6H4X-2)Br(PPh3)2] (X (3a), (3b), CHCH2 (3d)), and [Pd(μ-Br)(C6H4X-2)(PPh3)]2(X (4a), (4b)). Their reactions with XyNC (Xy 2,6-dimethylphenyl) depend on nature other ligands reaction conditions. The products these are mono- triinserted complexes. Among former [Pd{C(NXy)C6H4X-2}Br(L2)] (L2 bpy, (5a), (5b); L...
Cyclopalladation reactions are well known processes widely studied, because they represent a facile method for the activation of C–H bond in aromatic rings and have potential applications organic synthesis. A large variety N-containing ligands has been cyclometalated, including tertiary amines. Nevertheless, only very recently, general to ortho-palladate primary aryl-alkylamines reported. This review deals mainly with synthesis, but also structure reactivity, ortho-metalated complexes...
Cyclometalation of 3-(2-naphthyl)-d-alanine methyl ester is achieved by reacting the corresponding hydrochloride salt and Pd(OAc)2 in a 1:1 molar ratio (acetonitrile, room temperature, 6 days). Although chloro-bridged dimer (A) cannot be isolated pure form, addition RNC to reaction mixture affords mononuclear derivatives (R)-[Pd{κ2(C,N)-C10H6CH2CH(CO2Me)NH2-2}Cl(CNR)] (R = tBu (1a-tBu), Xy (C6H3Me2-2,6) (1a-Xy)). Similar complexes (S)-[Pd{κ2(C,N)-C8H5N(CH2CH(CO2Me)NH2)-2}Cl(CNR)] (1b-tBu),...
Phosphonium salts (Ph3PCH2CO2R)ClO4(R = Me or Et) react with [Au(acac)L′](acac acetylacetonate, L′= PPh3 AsPh3), displacing acac as acetylacetone and yielding cationic complexes of the corresponding phosphorus ylides L (L Ph3PCHCO2Me, PPh3; Ph3PCHCO2Et, AsPh3). These [Au(acac) L′] to give dinuclear species [(AuL′)2{µ-C(PPh3)CO2R}]ClO4(R Et, AsPh3; R Me, PPh3). The displacement ligand tetrahydrothiophene (tht) in [AuCl(tht)] by Ph3PCHCO2R (R forms [AuCl(L)], which (i) chlorine [AuCl3L] (ii)...
[AuCl(SMe2)] reacts with HC≡CR (R = bpyl 2,2′-bipyridine-5-yl (1), phtpyl phenyl-4-(2,2′:6′,2′′-terpyridine-4-yl) (2)) and NEt3 (1:1:3) to afford the polymers [Au(C≡CR)]n (3), (4)). The new alkyne HC≡Cphccbpyl (5, phccbpyl 4-C6H4C≡Cbpyl) has been prepared by Sonogashira coupling of 4-Me3SiC≡CC6H4I 1 followed desilylation resulting 4-Me3SiC≡Cphccbpyl. alkynyl Au(I) complexes [Au(C≡CR)L] bpyl, L PPh3 (6), PTol3 (7, Tol 4-MeC6H4), PEt3 (8); R phtpyl, XyNC (9), (10); phccbpyl, (11)) have...
Tetrahydrothiophen (tht) and/or chloride may readily be displaced from [ClAu(tht)] or [Cl3Au(tht)] with LiC6F5 to give novel organometallic anionic complexes of gold(I) gold(III).
[(PPh3)2N][Au(acac)2] (acac = acetylacetonate) reacts with terminal alkynes RC⋮CH to give [(PPh3)2N][Au(C⋮CR)2] (R H, tBu, SiMe3, CH2X (X Cl, Br, OH)) complexes. The reactions between [(PPh3)2N][Au(C⋮CH)2] and [(PPh3)2N][AuX2] I) [(PPh3)2N][Au(C⋮CH)X] Neutral mononuclear [Au(C⋮CR)(NHEt2)] tBu), [Au(C⋮CR)(PR‘3)] R‘ Ph, C6H4OMe-4; R CH2Cl, CH2Br, CH2OH, Cy cyclohexyl; C6H4OMe-4, Cy; Cy, C6H4OMe-4), [Au(C⋮CR)(CNtBu)] [Au(C⋮CR){C(NHtBu)(NEt2)}] tBu) or dinuclear [(AuL)2{μ-C⋮C(CH2)5C⋮C}] (L PPh3,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGold in organic synthesis. Preparation of symmetrical and unsymmetrical biaryls via carbon-carbon coupling from cis-diarylgold(III) complexesJose Vicente, Maria Dolores Bermudez, Jaime EscribanoCite this: Organometallics 1991, 10, 9, 3380–3384Publication Date (Print):September 1, 1991Publication History Published online1 May 2002Published inissue 1 September...
Two new types of gold–gold interactions are described. Crystals 1 contain polymeric chains with short contacts between cationic gold centers, while in 2 one atom is coordinated nearly trigonally by three others.
The complex [[graphic omitted]Ph-2)Cl2] reacts with [HgR2](R = C6H4NO2-2 or C6F5) and NMe4Cl (2 : 1 2) to give omitted]Ph-2)(R)Cl][R C6H4NO2-2, (1); C6F5(2)]. Similarly, omitted])Cl2](3)[C–N C6H3(NNC6H4Me-4′)-2-Me-5], prepared by the reaction of [AuCl3(tht)](tht tetrahydrothiophene) [Hg(C–N)Cl] (1 1), Tl(acac)(Hacac =acetylacetone)(1 1) omitted])(acac-C)Cl](4). Reaction (2) PPh3(1 leads omitted]Ph-2)(C6F5)Cl(PPh3)](5), which upon standing in dichloromethane solution decomposes a mixture...
The ortho-metalated complex (S,S)-[Pd2{κ2(C,N)-C6H4CH2CH(CO2Me)NH2-2}2(μ-Br)2] (1b) can be prepared by refluxing in acetonitrile equimolecular amounts of Pd(OAc)2 and l-phenylalanine methyl ester hydrochloride, followed addition an excess NaBr. Complex 1b reacts with 4-picoline to give the mononuclear derivative (S)-[Pd{κ2(C,N)-C6H4CH2CH(CO2Me)NH2-2}2Br(NC5H4Me-4)] (2), whose crystal structure has been determined X-ray diffraction. precursor 1b,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of gold(I), gold(III), and silver(I) complexes with ylide ligands derived from carbonylbis(methylenetriphenylphosphonium)diperclorate. Crystal molecular structures [Au2{.mu.-{{CH(PPh3)}2CO}}2](ClO4)2, [(Ph3PCCl2)2CO][AuCl4](ClO4), [(AuL)2{.mu.-{C(PPh3)C(O)CH(PPh3)(AuL)}}](ClO4)2 (L = PPh3), [{Au(PMe2Ph)}4{.mu.-{{C(PPh3)}2CO}}](ClO4)2Jose Vicente, Maria Teresa Chicote, Isabel Saura-Llamas, Peter G. Jones, Karen Meyer-Baese, Cristina Freire...
1-(2-Iodophenyl)-3-p-tolylurea (1) reacts with Pd(dba)2 ([Pd2(dba)3]·dba; dba = dibenzylideneacetone) in the presence of appropriate ligands to give ortho-palladated arylureas [Pd{C6H4NHC(O)NHTo-2}IL2] (To C6H4Me-4; L2 tbubpy (4,4'-di-tert-butyl-2,2'-bipyridine) (2a), tmeda (N,N,N',N'-tetramethylethylenediamine) (2b); L PPh3 (2c)). Reaction 2b Tl(TfO) (TfO triflate, CF3SO3) results formation cyclopalladated [Pd{κ2C,O-C6H4NHC(O)NHTo-2}(tmeda)]OTf (3b). The latter yield...
The reaction between [AuCl(tht)](tht = tetrahydrothiophene) and the ylide Ph3PCHC(O)NMe2 gives [AuCl{CH(PPh3)C(O)NMe2}]1, which reacts with chlorine to [AuCl3{CH(PPh3)C(O)NMe2}]2 same NaClO4 form [Au{CH(PPh3)C(O)NMe2}2]ClO43. analogous silver complex [Ag{CH(PPh3)C(O)NMe2}2]ClO44 is obtained by of AgClO4 in molar ratio 1 : 2. phosphonium salt [Ph3PCH2C(O)NMe2]ClO4 [Au(acac)(PPh3)](acac acetylacetonate) [Au{CH(PPh3)C(O)NMe2}(PPh3)]ClO45 or [(AuPPh3)2{µ-C(PPh3)C(O)NMe2}]ClO46 depending on...