A5014552103- CAR-T cell therapy research
- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- Cardiac Valve Diseases and Treatments
- Acute Lymphoblastic Leukemia research
- Coronary Interventions and Diagnostics
- Retinoids in leukemia and cellular processes
- Cardiac Imaging and Diagnostics
- CRISPR and Genetic Engineering
- Virus-based gene therapy research
- Multiple Myeloma Research and Treatments
- Psoriasis: Treatment and Pathogenesis
- Cardiovascular Function and Risk Factors
- Hematopoietic Stem Cell Transplantation
- Cytokine Signaling Pathways and Interactions
- Acute Myeloid Leukemia Research
- Pluripotent Stem Cells Research
- Histone Deacetylase Inhibitors Research
- COVID-19 Clinical Research Studies
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Thermal Regulation in Medicine
- COVID-19 Impact on Reproduction
- Protein Degradation and Inhibitors
- Coronary Artery Anomalies
Tehran University of Medical Sciences
2018-2023
Moffitt Cancer Center
2023
Universal Scientific Education and Research Network
2021
University of Tehran
2021
Iran University of Science and Technology
2017
Cleveland Clinic
1998-2005
Cleveland Foundation
1998
The successful ex vivo expansion of T-cells in great numbers is the cornerstone adoptive cell therapy. We aimed to achieve most optimal T-cell condition by comparing at various seeding densities, IL-2 concentrations, and bead-to-cell ratios. we first expanded peripheral blood mononuclear cells (PBMCs) a healthy donor range 20 500 IU/mL 125 × 103 1.5 106 cell/mL, 1:10 10:1 B:C (Bead-to-cell) ratios compared results. then PBMC three donors using optimized conditions examined growth kinetics....
Carotid stenting has emerged as an alternative revascularization modality to endarterectomy for the treatment of carotid artery disease. Restenosis a stent may be occasionally seen. Our experience in intravascular radiation therapy coronary restenosis provided us opportunity explore this strategy restenosis. We report our initial with brachytherapy after stenting.
Although AML-M3 (APL) and HLA-DR negative non-APL are characterized by antigen, they different entities with similar morphology in some cases. The aim of this study is the precise, differential diagnosis APL from flow cytometry to narrow window. Bone marrow or blood samples 580 AML patients were analyzed, molecular analysis performed for disorders. In 105 patients, expression HLA-DR, CD33, CD117, CD11b, CD64, CD34, CD9 myeloperoxidase staining pattern evaluated. Fifty-six diagnosed APL, 49...
Abstract Background Cytokine-induced killer (CIK) cells have shown promising results in adoptive immunotherapy. However, serum may play a determining role the large-scale expansion of these for clinical applications. According to Good Manufacturing Practice (GMP) guidelines reduce use animal products cell-based therapies; therefore, this study sought investigate impact origin and reduced concentration on pattern cell function. Methods Peripheral blood mononuclear (PBMCs) isolated from...
The goal of this preclinical investigation was to evaluate the healing tapered roughened surfaced dental implants that were delivered by either a manual torque limiting wrench or an electronically controlled device. Three canines underwent bilateral extraction third and fourth premolars first molar. sites allowed heal for 2 months before two placed bilaterally. All animals normal process. One animal sacrificed at 1 month remaining perform histologic evaluations including bone-to-implant...
He has had fever, chills, night sweats, shortness of breath, and productive cough for 3 days. What is the cause?
Abstract- Rheumatoid arthritis (RA) is the most common autoimmune inflammatory disease of joints among adults. Regulatory T cells (Treg) control immune responses in this illness. Through expression FoxP3, a Treg transcription factor, Vitamin D keeps diseases check. Yet, molecular mechanism FoxP3 by vitamin not well-inspected. It may influence via epigenetic changes. This study aimed to investigate correlation between plasma levels and demethylation TSDR region Foxp3 promoter patients with...
This paper introduces a device, algorithm and graphical user interface to obtain anthropometric measurements of foot.Presented device facilitates obtaining scale image processing by taking one from side foot underfoot simultaneously.Introduced minimizes noise criterion, which is suitable for object detection in single images outperforms famous thresholding methods when lighting condition poor.Performance image-based method compared manual method.Image-based average was 4mm less than actual...