Sampath Chinnam

ORCID: 0000-0002-5334-9076
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Research Areas
  • Synthesis and biological activity
  • Synthesis and Characterization of Heterocyclic Compounds
  • Organophosphorus compounds synthesis
  • Computational Drug Discovery Methods
  • Synthesis and Reactivity of Sulfur-Containing Compounds
  • Nanocomposite Films for Food Packaging
  • Graphene and Nanomaterials Applications
  • Multicomponent Synthesis of Heterocycles
  • Cholinesterase and Neurodegenerative Diseases
  • Carbon and Quantum Dots Applications
  • Thermochemical Biomass Conversion Processes
  • Nanoparticles: synthesis and applications
  • Click Chemistry and Applications
  • Phytochemicals and Antioxidant Activities
  • Advanced Photocatalysis Techniques
  • Essential Oils and Antimicrobial Activity
  • Nonlinear Optical Materials Research
  • X-ray Diffraction in Crystallography
  • Crystallography and molecular interactions
  • Advanced Nanomaterials in Catalysis
  • biodegradable polymer synthesis and properties
  • Natural Antidiabetic Agents Studies
  • Alzheimer's disease research and treatments
  • Advanced biosensing and bioanalysis techniques
  • Metal complexes synthesis and properties

M S Ramaiah University of Applied Sciences
2022-2025

Visvesvaraya Technological University
2022-2025

University of Lahore
2024

The University of Texas at El Paso
2024

Dr. D. Y. Patil Medical College, Hospital and Research Centre
2023

Dr. D.Y. Patil Vidyapeeth, Pune
2023

Heidelberg University
2023

Tribhuvan University Teaching Hospital
2023

Bangalore Medical College and Research Institute
2020

University of KwaZulu-Natal
2017

Waste oil treatment and the burning of fossil fuels are causing environmental problems, thus using waste oils as pyrolysis feedstock to produce high-grade biofuels is receiving a lot attention. Higher hydrogen volatile matter contents make them an optimal raw material for biofuel production. Conversely, attaining satisfactory effects employing traditional disposal methods such gasification, solvent extraction, transesterification, membrane technology, hydro-treating strenuous. Clean secure...

10.1016/j.jfueco.2024.100108 article EN cc-by-nc-nd Fuel Communications 2024-02-01

ABSTRACT The increasing demand for sustainable food packaging has driven the development of films based on biopolymers. However, enhancing their functional properties remains a challenge. In current study, potato starch–pectin (PSP) composite were fabricated and enriched with juniper berry essential oil (JBEO) to improve physicochemical properties. effects incorporating different concentrations JBEO (0.1%–1% v/v) various PSP‐based evaluated, including surface color, transparency, barrier...

10.1002/fsn3.4688 article EN cc-by Food Science & Nutrition 2025-01-01

Nanoparticles have received much attention in biomedical applications due to their unique physicochemical properties. The metal/metal oxide nanoparticles are involved various applications, including drug delivery, therapy, and diagnosis. Subsequently, many hazardous chemicals organic solvents were utilized synthesize the metallic nanoparticles. Therefore, green synthesis came into limelight overcome economic environmental burden. represents production of that reduce or terminate use...

10.1016/j.jddst.2022.103305 article EN cc-by Journal of Drug Delivery Science and Technology 2022-04-08

The inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) and papain-like (PLpro) prevents viral multiplications; these enzymes have been recognized as one the most favorable targets for drug discovery against SARS-CoV-2. In present study, we screened 225 phytocompounds in 28 different Indian spices to identify compounds potential inhibitors SARS-CoV-2 Mpro PLpro. Molecular docking, molecular dynamics simulation, mechanics Poisson-Boltzmann surface...

10.1016/j.sjbs.2022.02.028 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2022-02-25

In the present study novel heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) (1, 2, 3, 4a-e 5a-e) were designed synthesized investigated for their antimicrobial (against selected bacteria fungi) anticancer potential. The molecules 4e 5e 4-fluoro phenyl benzyl substituents showed promising (antibacterial antifungal activities with MICs ranging between 0.5 8 µg/mL. Compounds 3 exhibited potent activity an IC50 value of 0.49 ± 1.45 µM against human gastric...

10.1016/j.jscs.2022.101447 article EN cc-by-nc-nd Journal of Saudi Chemical Society 2022-03-03

In recent years, zinc oxide nanoparticles (ZNPs) have gained tremendous attention attributed to their unique properties. It is the most desirable group of nanostructures as far both structure and properties are concerned. an adaptable material that has distinctive properties, such high sensitivity, large specific area, non-toxicity, good compatibility, a isoelectric point, which favors it be considered with few exceptions. They utilized in expanding number mechanical items, for example,...

10.1016/j.jscs.2023.101774 article EN cc-by-nc-nd Journal of Saudi Chemical Society 2023-11-25

A new series of 3-aryl/heteroaryl-2-(1H-tetrazol-5-yl) acrylamides have been synthesized through catalyst-free, one-pot cascade reactions, utilizing click chemistry approach and evaluated for their anti-COVID activities against two proteins in silico. The structural properties the molecules were based on DFT calculations. Total energy tetrazole compounds obtained computational analysis which indicate high stability compounds. Frontier Molecular Orbitals (FMO) associated energies molecular...

10.1080/10406638.2022.2036778 article EN Polycyclic aromatic compounds 2022-02-16

10.1016/j.jarmap.2022.100400 article EN Journal of Applied Research on Medicinal and Aromatic Plants 2022-05-25

AbstractStructural modifications of ethyl-3-((5-bromopyridin-2-yl)imino)butanoate ester enhances its biological activities. In the present work, synthesis a Schiff base by reacting 2-amino-5-bromo pyridine and ethyl acetoacetate was reported. Electronic properties were investigated computational method density functional theory (DFT). The pass prediction score supported anti-viral efficacy which satisfied Lipiniski rule overall HOMO-LUMO. most important part this investigation docking study...

10.1080/10406638.2023.2173618 article EN Polycyclic aromatic compounds 2023-02-17

Abstract Graphene-based nanomaterials (graphene, graphene oxide, reduced quantum dots, graphene-based nanocomposites, etc.) are emerging as an extremely important class of primarily because their unique and advantageous physical, chemical, biological, optoelectronic aspects. These features have resulted in uses across diverse areas scientific research. Among all other applications, they found to be particularly useful designing highly sensitive biosensors. Numerous studies established...

10.1186/s11671-024-04032-6 article EN cc-by Discover Nano 2024-06-17

In the present study, a new series of α-Aminophosphonates bearing 6-amino-1,3-dimethyluracil was synthesized in good to excellent yields (78–95%) by one-pot, three-component reaction 6-amino-1,3-dimethyluracil, aromatic aldehydes and diethylphosphite via Kabachnik–Fields using an eco-friendly Eaton's reagent. All compounds were screened for vitro antioxidant studies 2,2-diphenyl-1-picrylhydrazyl (DPPH) hydrogen peroxide (H2O2) methods. Among bioactive molecules, 4a, 4d, 4g, 4h exhibited...

10.1080/10799893.2020.1722166 article EN Journal of Receptors and Signal Transduction 2020-02-05

Abstract In the history of catalysis and organic synthesis, boric chemistry has been developed into one most varied practical disciplines. Several useful Suzuki–Miyaura cross-coupling (SMC) reactions as well hydroborylation are regarded essential tools inside chemical synthesis toolkit accompanied by researchers industry or academia. Novel less electrically sterically ongoing carbon–boron synthetic reagents is carried out to ensure a unique coupling reaction utilizing metals along with these...

10.1186/s43094-023-00520-1 article EN cc-by Future Journal of Pharmaceutical Sciences 2023-08-11

The current research centred on estimating kinetic parameters and examining the composition of pyrolysis vapours from neem seeds COVID-19 waste nitrile gloves (NG) using Pyro-GC–MS. Owing to intricacy co-pyrolysis process, were studied KAS, OFW, FM, VZ models. Biomass plastic mixed in different proportions (1:1, 3:1, 5:1), whereas feed catalyst was at 5:1 8:1, respectively. estimation NMS NG confirmed that 3:1 ratio feeds-to-catalyst found be most effective producing maximum hot vapours....

10.1016/j.biteb.2024.101899 article EN cc-by Bioresource Technology Reports 2024-07-08
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