A5086718203- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Mechanisms and Treatments
- Anesthesia and Pain Management
- Nausea and vomiting management
- Pharmacological Effects of Natural Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuropeptides and Animal Physiology
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Pediatric Pain Management Techniques
- Non-Invasive Vital Sign Monitoring
- Atomic and Subatomic Physics Research
- Optical Imaging and Spectroscopy Techniques
- Pain Management and Opioid Use
- Nerve injury and regeneration
Chungnam National University
2020-2024
Chungnam National University Hospital
2020
National University College
2020
New Generation University College
2020
Activation of nuclear factor-kappa B (NF-κB) in microglia plays a decisive role the progress neuropathic pain, and inhibitor kappa (IκB) is protein that blocks activation NF-κB degraded by kinase subunit beta (IKBKB). The IKBKB to break down IκB, which activity NF-kB. Therefore, it prevents NK-kB. This study investigated whether pain can be reduced spinal nerve ligation (SNL) rats reducing delivering small interfering RNA (siRNA)-encapsulated poly (lactic-co-glycolic acid) (PLGA)...
Activation of CX3CR1 in microglia plays an important role the development neuropathic pain. Here, we investigated whether pain could be attenuated spinal nerve ligation (SNL)-induced rats by reducing microglial activation through use poly(D,L-lactic-co-glycolic acid) (PLGA)-encapsulated small-interfering RNA (siRNA) nanoparticles. After confirming efficacy and specificity siRNA, as evidenced its anti-inflammatory effects lipopolysaccharide-stimulated BV2 cells vitro, PLGA-encapsulated siRNA...
Background and Objectives: The effect of supra-inguinal fascia iliaca compartment block (SI-FICB) in hip arthroscopy is not apparent. It also controversial whether SI-FICB can the obturator nerve, which may affect postoperative analgesia after arthroscopy. We compared analgesic effects before implementation nerve into for Materials Methods: retrospectively reviewed medical records 90 consecutive patients who underwent from January 2017 to August 2019. Since 2018, protocol was changed with...
Desflurane is known to have a larger vasodilatory effect than that of sevoflurane. However, its generalizability and size in actual clinical practice are yet be proven. Patients aged ≥ 18 years who underwent noncardiac surgery under general anesthesia using inhalation anesthetics (desflurane or sevoflurane) were matched 1:1 by propensity score. The mean intraoperative perfusion index (PI) each patient compared between the two groups. Propensity score matching 1680 patients study cohort...
Opioid-sparing effects of nefopam during patient-controlled analgesia (PCA) are well demonstrated. We hypothesized that postoperative pain control with an opioid-equivalent dose as a single analgesic agent for PCA would not be inferior to fentanyl in laparoscopic gynecologic surgery. In total, 135 patients were randomly assigned the N (nefopam 200 mg), NF (fentanyl 500 mcg + 100 and F 1000 mcg) groups (n = 45 per group). The primary outcome was numerical rating scale (NRS) score at rest 6 h...
BACKGROUND: Unlike pulse pressure variation (PPV), the Plethysmographic Variability Index (PVI) has shown limited and heterogenous reliability in predicting fluid responsiveness, especially during dynamic intraoperative periods.METHODS: This retrospective study assessed accuracy of PVI high PPV (>13%) using resolution vital records acquired neurosurgery. In addition, a new set cut-off values for >13% was derived gray-zone approach. included consecutive patients who underwent neurosurgery...
Abstract Background: Arthroscopic shoulder surgery tends to cause a drop in blood pressure due the beach chair position used during procedure, including activation of Bezold-Jarisch reflex. We hypothesized that patients with low undergoing arthroscopic would also have reduced renal function after surgery.Methods: The medical records (N = 643) between July 2013 and May 2015 were examined. vital signs measured at 5-minute intervals, number non-invasive (NIBP) measurements upper arm dropping...