A5017947422- COVID-19 Clinical Research Studies
- Lung Cancer Research Studies
- Radiopharmaceutical Chemistry and Applications
- Infection Control and Ventilation
- Effects of Radiation Exposure
- Neuroendocrine Tumor Research Advances
- Urinary and Genital Oncology Studies
- Prostate Cancer Treatment and Research
- COVID-19 and healthcare impacts
- Particle accelerators and beam dynamics
- DNA Repair Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Mass Spectrometry Techniques and Applications
- Radiation Therapy and Dosimetry
- Vaccine Coverage and Hesitancy
- PARP inhibition in cancer therapy
- Medical Imaging Techniques and Applications
- Gyrotron and Vacuum Electronics Research
- Lung Cancer Treatments and Mutations
- Bladder and Urothelial Cancer Treatments
Steve Biko Hospital
2023-2024
University of Pretoria
2023-2024
A 61-y-old man underwent [18F]FDG PET/CT for staging of right-lung small cell neuroendocrine carcinoma. The images ([Fig. 1A][1]) showed a tracer-avid mass. As part feasibility study approved by the University Pretoria Ethics Committee, subject gave written informed consent to
Patients with cancer are presumed to be vulnerable an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and clinical outcomes due the immunocompromised state mediated by their underlying malignancies therapy. The aim this study was estimate SARS-CoV-2 seroprevalence, following second fourth waves in solid tumour patients attending Steve Biko Academic Hospital (SBAH) for diagnosis treatment cancer. We used single-prick COVID-19 IgG/IgM Rapid Test...
Introduction: PARP (poly[ADP-ribose] polymerase) inhibitors (PARPi) are effective oncology agents for tumors harboring certain genetic mutations that make them resistant to conventional therapies such as chemotherapy and radiotherapy. We demonstrate, the first time, iodine-123 radiolabeled PARPi SPECT/CT imaging can be used a marker of upregulation predictor resistance in patient with small cell neuroendocrine tumor.
Introduction: 225Ac-PSMA in its various drug forms has been reported as a competitive alternative or adjunct therapy castration resistance male prostate cancer. While it shown great efficacy to those who respond well, much effort needs be directed understanding the stability and radiobiology of this derivatives. Under principles Good Radiopharmacy Practice (GRPP), we produced at least three [225Ac]-PSMA bolus injections cleanroom environment approved under quality control (QC) testing...
A correlation between neutralization activity after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and protection against disease 2019 (COVID-19) has been demonstrated by several studies. Here, we detect SARS-CoV-2 neutralizing antibody (NAB) production in COVID-19 patients from the Steve Biko Academic Hospital complex (SBAH), South Africa (SA). Samples (mild to severe) were collected. rapid assays, genotyping (Delta Omicron variants) enzyme-linked immunosorbent...