A5078885991- Atrial Fibrillation Management and Outcomes
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Erythropoietin and Anemia Treatment
- Venous Thromboembolism Diagnosis and Management
- Healthcare Systems and Practices
- Health Systems, Economic Evaluations, Quality of Life
- Thermal Regulation in Medicine
- Antimicrobial Resistance in Staphylococcus
- Viral Infections and Immunology Research
- Microscopic Colitis
- Pericarditis and Cardiac Tamponade
- Ultrasound in Clinical Applications
- Biosimilars and Bioanalytical Methods
- Orthopedic Infections and Treatments
- Cardiac Arrest and Resuscitation
- Pneumothorax, Barotrauma, Emphysema
- Neurological Disorders and Treatments
- Peptidase Inhibition and Analysis
- Quality and Safety in Healthcare
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Climate Change and Health Impacts
- Antibiotic Use and Resistance
New Cross Hospital
2022-2024
Birmingham City Hospital
2024
University of Birmingham
2023-2024
University Hospitals Birmingham NHS Foundation Trust
2024
Queen Elizabeth Hospital
2024
NIHR Birmingham Biomedical Research Centre
2024
Dumfries and Galloway Royal Infirmary
2023
Shrewsbury and Telford Hospital NHS Trust
2023
The Royal Wolverhampton NHS Trust
2022
Good Hope Hospital
2021
Artificial intelligence (AI) is increasingly being utilized in healthcare. This article provides clinicians and researchers with a step-wise foundation for high-value AI that can be applied to variety of different data modalities. The aim improve the transparency application methods, potential benefit patients routine cardiovascular care. Following clear research hypothesis, an AI-based workflow begins selection pre-processing prior analysis, type (structured, semi-structured, or...
Abstract Background and Aims The role of gender in decision-making for oral anticoagulation patients with atrial fibrillation (AF) remains controversial. Methods population cohort study used electronic healthcare records 16 587 749 from UK primary care (2005–2020). Primary (composite all-cause mortality, ischaemic stroke, or arterial thromboembolism) secondary outcomes were analysed using Cox hazard ratios (HR), adjusted age, socioeconomic status, comorbidities. Results 78 852 included AF,...
The prevention of thromboembolism in atrial fibrillation (AF) is typically restricted to patients with specific risk factors and ignores outcomes such as vascular dementia. This population-based cohort study used electronic healthcare records from 5,199,994 primary care (UK; 2005-2020). A total 290,525 (5.6%) had a diagnosis AF were aged 40-75 years, which 36,340 no history stroke, low perceived stroke based on clinical oral anticoagulant prescription. Matching was performed for age, sex...
Abstract Aims The aim is to describe the rationale, design, delivery, and baseline characteristics of Stroke prevention rhythm control Treatment: Evaluation an Educational programme European society cardiology in a cluster-Randomized trial patients with Atrial Fibrillation (STEEER-AF) trial. Methods results STEEER-AF pragmatic designed objectively robustly determine whether guidelines are adhered routine practice evaluate targeted educational for healthcare professionals. Seventy centres...
Background Iron deficiency (ID) has been shown to be a significant co-morbidity in patients with heart failure (HF), independent of their anaemia status. Correction ID improve quality life, recurrent hospitalizations and morbidity. A improvement project was designed the assessment treatment iron HF our tertiary care centre. Methods results An initial baseline dataset collected, followed by two cycles interventions help admitted hospital over two-month period. The Plan-Do-Study-Act (PDSA)...
This case report describes the successful treatment of severe accidental hypothermia with cardiopulmonary bypass (CPB). A known intravenous drug misuser aged 22 years was found to be unresponsive at his home (winter evening) a Glasgow coma scale 3/15. In ambulance, patient went into cardiac arrest, resuscitation being started. On arrival emergency department, he had core body temperature 27°C which refractory conservative management. He underwent femoro-femoral CPB, in rewarming slowly. The...
<h3>Introduction</h3> Heart failure (HF) and atrial fibrillation (AF) are increasingly prevalent associated with substantial morbidity. When HF AF co-exist, the outcome profile is significantly worse than for either condition in isolation. Ethnic background known to influence disease outcomes treatment efficacy, but there limited knowledge about how HF, ethnicity interact on mortality hospital admission. <h3>Methods</h3> Individual patient data were obtained from 12 randomized controlled...
A 43-year-old man was referred to a specialised liver unit with progressive abdominal distension and sarcopoenia. He had background of moderate-to-high alcohol intake. His exercise tolerance appropriate for his age, he denied having exertional dyspnoea or orthopnoea. On examination, there shifting-dullness abdomen, bilateral pitting oedema, an elevated jugular venous pressure sarcopenia. Other than clinical ascites, were no stigmata disease. observations stable, urine output acceptable. His...
This is a commentary article, there no abstract section.
<h3>Background</h3> Thromboembolism in patients with atrial fibrillation (AF) can be prevented, however oral anticoagulation is typically reserved for older or those specific historical comorbidities. Risk scores are widespread use, but limited predictive accuracy stroke and no consideration of current major challenges such as dementia. This study provides contemporary data on the risk thromboembolism, including both cardiac cerebral damage. <h3>Methods</h3> Population-based matched cohort...
<h3>Introduction</h3> Sarcoidosis is a multi-systemic inflammatory disorder characterised by non-caseating granulomata. Cardiac sarcoidosis (CS) typified the presence of myocardial inflammation and confers adverse prognosis, as it can be associated with conduction abnormalities, congestive heart failure, ventricular arrhythmias (VA) sudden cardiac death. European Society Cardiology (ESC) guidelines advocate implantable cardioverter-defibrillator (ICD) implantation concurrent...
<h3>Introduction</h3> Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, accounting for nearly 30% total deaths based on World Health Organization (WHO) statistics. Cholesterol a key risk factor atheroma coronary heart disease. Lipid-lowering drugs play crucial role in secondary prevention CVD. Current national guidelines recommend checking lipid profile all patients admitted with acute syndrome (ACS). Lipid profiles should be checked every patient...
<h3>Introduction</h3> Recent evidence has shown that iron deficiency is a significant co-morbidity in heart failure patients independent of their anaemia status. Iron present about 55% chronic and 80% acute been associated with reduced exercise capacity, recurrent hospitalisations, high cardiovascular all-cause mortality. A quality improvement project was therefore designed to improve the diagnosis treatment our tertiary care centre. <h3>Methods</h3> An initial baseline dataset collected,...
<h3>Introduction</h3> Vedolizumab is a fully humanised monoclonal IgG-1 antibody. It selectively inhibits the interaction between α4β7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1). approved for treatment of moderate to severely active IBD. This study aimed provide real-world data on drug effectiveness in anti-TNF exposed population with high disease burden. <h3>Methods</h3> A retrospective cohort all patients commenced at Good Hope Hospital, Birmingham, UK was...