- Celiac Disease Research and Management
- Child Nutrition and Feeding Issues
- Liver Disease Diagnosis and Treatment
- Microscopic Colitis
- Liver Disease and Transplantation
- Digestive system and related health
- Organ Transplantation Techniques and Outcomes
- Food Allergy and Anaphylaxis Research
- Gastroesophageal reflux and treatments
- Mast cells and histamine
- Child Nutrition and Water Access
- Gastrointestinal disorders and treatments
- Helicobacter pylori-related gastroenterology studies
- Immunodeficiency and Autoimmune Disorders
- Hepatitis Viruses Studies and Epidemiology
- Congenital gastrointestinal and neural anomalies
- Drug-Induced Adverse Reactions
- Inflammatory Bowel Disease
- Clinical Nutrition and Gastroenterology
- Gastrointestinal motility and disorders
- Infant Health and Development
- Hemoglobinopathies and Related Disorders
- Respiratory viral infections research
- Streptococcal Infections and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
Istanbul Aydın University
2023-2024
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2020-2023
Sağlık Bilimleri Üniversitesi
2020-2022
University of Health Science
2021
Bakırköy Psychiatric Hospital
2020
Ministry of Health
2020
Istanbul University-Cerrahpaşa
2016-2018
Istanbul University
2016-2018
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2008-2011
Many screening methods, such as the Screening Tool Risk on Nutritional Status and Growth (STRONGkids) Pediatric Yorkhill Malnutrition Score (PYMS), have been developed to detect malnutrition in pediatric patients. We aimed explore prevalence of risk hospitalized children via symptoms identification contributing factors, examine efficacy tools for children.STRONGkids PYMS were applied 1513 inpatients at 37 hospitals 26 cities from different regions Turkey. Physical measurements collected...
Myosin Vb (MYO5B) is a motor protein that facilitates trafficking and recycling in polarized cells by RAB11- RAB8-dependent mechanisms. Biallelic MYO5B mutations are identified the majority of patients with microvillus inclusion disease (MVID). MVID an intractable diarrhea infantile onset characteristic histopathologic findings requires life-long parenteral nutrition or intestinal transplantation. A large number such eventually develop cholestatic liver disease. Bi-allelic also subset...
Congenital diarrheal disorders (CDD) comprise > 50 monogenic entities featuring chronic diarrhea of early-onset, including defects in nutrient and electrolyte absorption, enterocyte polarization, enteroendocrine cell differentiation, epithelial integrity. Diarrhea is also a predominant symptom many immunodeficiencies, congenital glycosylation, some the vesicular sorting transporting machinery. We set out to identify etiology an intractable 2 consanguineous families by whole-exome sequencing,...
Abstract Aim The prevalence of congenital cerebral palsy (CP) worldwide ranges from 0.15 to 0.4%. CP causes several gastrointestinal complications that inhibit normal eating behavior. This single-center observational study aimed determine the tolerability and benefits percutaneous endoscopic gastrostomy (PEG) in pediatric patients with malnutrition. Materials Methods included 41 All patient data were retrospectively obtained Bakırköy Dr. Sadi Konuk Research Training Hospital, Department...
The aim of this study was to compare the accuracy rate liver stiffness calculated by shear wave elastography with biopsy results in obese and overweight children.Obese children between 3 18 years age, who had hepatic steatosis a healthy control group were included study. A blood sample obtained for laboratory tests performed all subjects. Liver biopsies only patients hepatosteatosis, providing permission biopsy, whom procedure not contraindicated.A cohort 142 (78 overweight/obese 64 healthy)...
Benzalkonium chloride (BAC) is a caustic agent which used in farms, homes and hospitals for cleaning skin wounds as an antiseptic solution. It may lead to digestive system injuries case of ingestion. We present two-days-old newborn was carried the emergency unit with complaints poor breastfeeding, uneasiness crying 4-6 hours. Her mom confessed that she had given spoon 10% BAC solution her cough. Initial laboratory tests were normal ranges. A gastroscopy performed second hour admission...
We aimed to evaluate the frequency of extraintestinal manifestations (EIM) in children with inflammatory bowel disease (IBD) and correlation EIM activity index, type age.Records patients who were under 18 years age followed up diagnosis IBD included study. The demographic characteristics patients, sex recorded. When enrolled study indexes calculated by examining physical examination laboratory values their last visits, using Pediatric Ulcerative Colitis Activity Index (PUCAI) (UC) Crohn's...
To assess the effects of a gluten-free diet on bone structure in children with celiac disease using fractal analysis panoramic radiographs.A total 49 patients aged 6 to 13 years, separated into two groups as previously and newly diagnosed, control group 32 healthy individuals were evaluated. In diagnosed disease, body mass index Z-scores calculated, calcium, alkaline phosphatase, vitamin D3, parathormone levels measured, mineral density obtained from dual energy x-ray absorptiometry. all...
Tufting enteropathy (TE) is caused by recessive EPCAM mutations, and characterized intractable diarrhea of congenital onset disorganization enterocytes. TE generally requires parenteral nutrition (PN) during childhood or intestinal bowel transplantation. We report three unrelated families with six children TE. highlight the high rate disease-related mortality. observe adequate weight gain PN, but low to normal stunted body length, supporting recent notion that a short stature might be...
Annular pancreas is a rare congenital anomaly that consists of ring pancreatic tissue partially or completely encircling the second part duodenum. It can affect anyone from neonates to adults, and difficult diagnose because it present in wide range clinical conditions. Although cases have also been reported symptomatic are often referred infancy early childhood. A 17-year-old female patient who was diagnosed as having annular reported. The had non-bilious vomiting accompanied by abdominal...
Objective: Helicobacter pylori is rdescribed as the major etiological factor for gastritis and also associated with gastroesophageal reflux disease, vitamin B12 deficiencies.Therefore, we aimed to evaluate relationship between status well determine prevalence of esophagitis in children H.pylori infections.Method: A total number 556 who underwent eso-gastro-duodenoscopy were evaluated retrospectively.Diagnosis H infection, esophagitis, was performed histopathologic examination.Patients...
We aimed to evaluate type, frequency, and variety of pathogenic variants according clinical demographic features children diagnosed with cystic fibrosis (CF). Twenty-five CF patients were evaluated retrospectively. Patients' demographics, physical examination, imaging, laboratory, molecular variant analysis findings evaluated. Phe508del was the most frequently (33.3%) detected variant, followed by point E92K, 1898 + lGA/7T/7T, 2789 5GA, respectively. Statistically higher rates in male...
Objective: Upper gastrointestinal bleeding (UGB) is one of the most important and serious cause emergency admission in childhood. The aim study was to evaluate etiological factors treatment approaches patients with UGB. Methods: In this retrospective study, children UGB admitted clinics Istanbul Health Sciences University Kanuni Sultan Suleyman Research Training Hospital, Bakirkoy Sadi Konuk Hospital Diyarbakir Children’s were evaluated between January 2014 August 2017. Results: Of 198...
Superior mesenteric artery syndrome, also known as Wilkie's Syndrome, is a life threatening clinical entity which developes result of obstructed second or third part duodenum compressed between aorta and superior artery.In this rare rapid weight loss accompanied by stomach ache, abdominal distension, lack appetite, nausea vomiting after meals.In patients admitted for acute abdomen, syndrome should be included in the differential diagnosis case preceeding loss.X-ray barium passage,...