A5005491871- Analytical chemistry methods development
- Analytical Chemistry and Chromatography
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Adsorption and biosorption for pollutant removal
- Graphene and Nanomaterials Applications
- Luminescence and Fluorescent Materials
- Molecular Sensors and Ion Detection
- Nanoparticle-Based Drug Delivery
- Electrochemical sensors and biosensors
- Nanoplatforms for cancer theranostics
- Pharmaceutical and Antibiotic Environmental Impacts
- Carbon and Quantum Dots Applications
- Mass Spectrometry Techniques and Applications
- Covalent Organic Framework Applications
- Polymer Surface Interaction Studies
- Advanced Photocatalysis Techniques
- Pesticide Residue Analysis and Safety
- Polydiacetylene-based materials and applications
- Protein purification and stability
- Iron Metabolism and Disorders
- Forensic Toxicology and Drug Analysis
- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Sensors
- Per- and polyfluoroalkyl substances research
Xi'an Jiaotong University
2016-2025
Zhongda Hospital Southeast University
2024
Qufu Normal University
2017-2022
China XD Group (China)
2014-2021
Beihang University
2021
Dian Diagnostics (China)
2021
Yunnan University
2021
First Affiliated Hospital of Xi'an Jiaotong University
2017
Zhejiang University
2016
Nankai University
2006-2012
A general method to prepare thin, molecularly imprinted polymer (MIP) coatings on magnetic Fe3O4 nanoparticles (NPs) with a uniform core–shell structure for the recognition and enrichment of protein was developed. Four proteins (bovine serum albumin (BSA, pI = 4.9), bovine hemoglobin (BHb, 6.9), pancreas ribonuclease (RNase A, 9.4) lysozyme (Lyz, 11.2)) different isoelectric points were chosen as templates. The protein-MIPs synthesized by combining surface imprinting sol–gel techniques....
In this work, the core–shell bovine hemoglobin (BHb)-imprinted superparamagnetic nanoparticles (Fe3O4@BHb-MIPs) were synthesized by combining for first time a surface imprinting technique and two-step immobilized template strategy. Initially, amino-functionalized Fe3O4 (Fe3O4@NH2) directly through facile one-pot hydrothermal method. Next, BHb was on of Fe3O4@NH2 non-covalent interactions. Then, siloxane co-polymerization Fe3O4@NH2–protein complex resulted in polymeric network molded around...
Prostate cancer is the most common malignancy diagnosed in men. Androgens are directly related to its pathogenesis. Inhibition of androgen receptor (AR) considered be promising therapeutic approach for treatment prostate cancer. In this study, a new type pH-responsive dual androgen-blocking nanodrug (FASC MIPs) based on molecularly imprinted polymer has been designed and synthesized. The could selectively sequester testosterone from tumor through specific molecular imprinting sites...
Schematic diagram of the preparation enzyme-responsive nanoplatform HA-CP@Fe 3 O 4 and its application in study antibacterial infection vivo .
Silica-based hybrid molecularly imprinted polymer (MIP) monoliths with good chiral recognition ability are synthesized (see figure) using a novel method, room temperature ionic liquid (RTIL)-mediated, non-hydrolytic sol–gel technique. The approach avoids the cracking and shrinking of bed during drying, which is commonly associated conventional processing, overcomes shortcomings organic-polymer-based MIP matrices, offers improved selectivity.
A kind of novel multi-stimuli responsive molecularly imprinted polymers with bovine serum albumin (BSA) as a dummy template (MSR-BSA-MIPs) was fabricated for specific recognition human (HSA) modulated affinity. The MSR-BSA-MIPs were prepared through free radical polymerization using vinyl modified magnetic nanoparticles substrates, (BSA), high amino acid sequence similarity but low price compared to HSA, the template, N-(3-(dimethylamino)-propyl)-methacrylamide (DMAPMA) and...
Nonspecific interactions of conjugated polymers (CPs) with various proteins prove to be a major impediment for researchers when designing suitable CP-based probe the amplified and selective recognition particular in complex body fluids. Herein, new strategy is presented precise specific monitoring clinically important serum albumin (SA) at nanomolar level using fluorescence resonance energy transfer (FRET)-modulated CP-surfactant ensembles as superior sensing materials. In brief, newly...
The synthesis of green and lightweight hollow double-layer magnetic adsorbents creates a roadmap for developing small molecule pollutants.
Hexavalent chromium [Cr(VI)] is considered a serious environmental pollutant that possesses hazardous effect on humans even at low concentrations. Thus, the development of bifunctional material for ultratrace-selective detection and effective elimination Cr(VI) from environment remains highly desirable scarcely reported. In this work, we explore an imidazolium-appended polyfluorene derivative PF-DBT-Im as sensitive/selective optical probe smart adsorbent ions with ultralow limit 1.77 nM...