Nadia Hindi
A5013226419- Sarcoma Diagnosis and Treatment
- Cardiac tumors and thrombi
- Vascular Tumors and Angiosarcomas
- Gastrointestinal Tumor Research and Treatment
- Soft tissue tumor case studies
- CAR-T cell therapy research
- Lymphoma Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Tuberous Sclerosis Complex Research
- Bone Tumor Diagnosis and Treatments
- Gastric Cancer Management and Outcomes
- Cancer Diagnosis and Treatment
- Platelet Disorders and Treatments
- Neurofibromatosis and Schwannoma Cases
- Tumors and Oncological Cases
- Oral and Maxillofacial Pathology
- Soft tissue tumors and treatment
- Cancer Genomics and Diagnostics
- Peptidase Inhibition and Analysis
- Angiogenesis and VEGF in Cancer
- Lung Cancer Treatments and Mutations
- HER2/EGFR in Cancer Research
- Gastrointestinal disorders and treatments
- COVID-19 and healthcare impacts
- Musculoskeletal synovial abnormalities and treatments
Hospital Universitario Fundación Jiménez Díaz
2021-2025
Universidad Autónoma de Madrid
2021-2024
Hospital Universitario Virgen del Rocío
2016-2023
Hospital Clínico Universitario Virgen de la Victoria
2022
Instituto de Biomedicina de Sevilla
2016-2021
Fondazione IRCCS Istituto Nazionale dei Tumori
2014-2021
Universidad de Sevilla
2017-2021
National Research Council
2020
Hospital Universitario La Paz
2012-2014
Background Sarcomas exhibit low expression of factors related to immune response, which could explain the modest activity PD-1 inhibitors. A potential strategy convert a cold into an inflamed microenvironment lies on combination therapy. As tumor angiogenesis promotes immunosuppression, we designed phase Ib/II trial test double inhibition (sunitinib) and PD-1/PD-L1 axis (nivolumab). Methods This single-arm, enrolled adult patients with selected subtypes sarcoma. Phase Ib established two dose...
Abstract Purpose: Perivascular epitheliod cell tumors (PEComas) are rare mesenchymal neoplasms for which the role of systemic treatments is not established as there no published prospective clinical trials or sufficiently large retrospective case series. The aim this study to clarify activity conventional chemotherapy and biological agents in advanced/metastatic PEComas. Experimental Design: This was an observational, retrospective, international that included patients with PEComa treated...
Preclinical data about the synergistic activity of radiotherapy (RT) and trabectedin have been reported. The combination RT in treating myxoid liposarcomas appears worth exploring.
About 500,000 patients with rare adult solid cancers (RASC) are diagnosed yearly in Europe. Delays and unequal quality of management impact negatively their survival. Since 2017, European reference networks (ERN) aim to improve the care disease. The steering committee EURACAN, including physicians, researchers review here previous actions, present objectives ERN EURACAN dedicated RASC. promoted centres, equal implementation excellence innovation Europe developed 22 clinical practice...
Abstract Background Alveolar soft part sarcoma (ASPS) is an exceedingly rare and orphan disease, without active drugs approved in the front line. Pazopanib trabectedin are licensed for treatment from second-line, but very little contradictory data available on their activity ASPS. Lacking ongoing and/or planned clinical trials, we conducted a multi-institutional study involving reference sites Europe, U.S., Japan, within World Sarcoma Network, to investigate efficacy of pazopanib...
Reference centers (RCs) are a key point for improving the survival of patients with soft-tissue sarcomas (STS). The aim this study was to evaluate selected items in management STS, comparing results between RC and local hospitals (LHs).Diagnostic therapeutic data from diagnosed January 2004 December 2011 were collected. Correlation outcome performed.A total 622 analyzed, median follow-up 40 months. Imaging primary tumor preoperatively (yes vs. no) correlated higher probability free surgical...
The effect of high-dose imatinib (800 mg/day) on survival in the adjuvant treatment patients with resected KIT exon 9-mutated gastrointestinal stromal tumors (GIST) is not established. Here, association dose and other clinicopathologic variables was evaluated a large multi-institutional European cohort.Data from 185 were retrospectively collected 23 GIST reference centers. Propensity score matching (PSM) inverse-probability weighting (IPTW) used to account for confounders. Univariate...