Hiroshi Kinoshita

ORCID: 0000-0002-5872-0719
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About
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Research Areas
  • Motor Control and Adaptation
  • Microbial Natural Products and Biosynthesis
  • Muscle activation and electromyography studies
  • Fungal Biology and Applications
  • Musicians’ Health and Performance
  • Tactile and Sensory Interactions
  • Entomopathogenic Microorganisms in Pest Control
  • Neuroscience and Neuropharmacology Research
  • Music Technology and Sound Studies
  • Plant Pathogens and Fungal Diseases
  • Microbial Metabolism and Applications
  • Diabetes Treatment and Management
  • Memory and Neural Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Neuropeptides and Animal Physiology
  • Action Observation and Synchronization
  • Plant biochemistry and biosynthesis
  • Silicone and Siloxane Chemistry
  • Receptor Mechanisms and Signaling
  • Neuroscience and Music Perception
  • Fungal and yeast genetics research
  • RNA and protein synthesis mechanisms
  • Enzyme Production and Characterization
  • Bacterial Genetics and Biotechnology
  • Music Therapy and Health

Japanese Red Cross Society Kyoto Daini Hospital
2025

Osaka Aoyama University
2016-2023

Kagawa University
1996-2020

Osaka University
2009-2018

Osaka International University
2004-2018

Osaka Prefecture University
2016

Tottori University
2011-2013

Tohoku University
2010

Toyama Prefectural University
2008-2009

Mahidol University
2009

The effects of two different systems on selected biomechanical parameters walking gait, while carrying loads varying magnitude, were investigated. Ten healthy males who not regularly engaged in tasks walked a distance 20 m for ten trials each the following five conditions: (i) normal without any external load; (ii) 20% and (iii) 40% body weight carried using backpack system; (iv) (v) doublepack system which distributed load equally between front back subjects. experimental set-up consisted...

10.1080/00140138508963251 article EN Ergonomics 1985-09-01

ABSTRACT Citrinin produced by Aspergillus , Penicillium and Monascus species is a polyketide compound that has nephrotoxic activity in mammals bactericidal toward gram-positive bacteria. To avoid the risk of citrinin contamination other fermentation products purpureus knowledge biosynthetic genes needed so citrinin-nonproducing strains can be generated. We cloned synthase (PKS) gene from M. with degenerate primers designed to amplify conserved region ketosynthase domain fungal PKS. A 13-kb...

10.1128/aem.71.7.3453-3457.2005 article EN Applied and Environmental Microbiology 2005-07-01

Summary Gamma‐butyrolactone signalling molecules are produced by many Streptomyces species, and several have been shown to regulate antibiotic production. In coelicolor A3(2) at least one γ‐butyrolactone (SCB1) has stimulate production, genes encoding proteins that involved in its synthesis ( scbA ) binding scbR characterized. Expression of these is autoregulated a complex mechanism involving the γ‐butyrolactone. this study, additional influenced ScbR were identified DNA microarray analysis,...

10.1111/j.1365-2958.2005.04543.x article EN Molecular Microbiology 2005-03-07

ABSTRACT Citrinin, a secondary fungal metabolite of polyketide origin, is moderately nephrotoxic to vertebrates, including humans. From the red-pigment producer Monascus purpureus , 21-kbp region flanking pksCT which encodes citrinin synthase, was cloned. Four open reading frames (ORFs) ( orf1 orf2 orf3 and orf4 ) in 5′-flanking one ORF orf5 3′-flanking were identified vicinity pksCT. encode homolog dehydrogenase (similarity, 46%), regulator 38%), an oxygenase 41%), oxidoreductase 26%),...

10.1128/aem.01979-06 article EN Applied and Environmental Microbiology 2007-06-23

We developed a simple and new insulin resistance index derived from glucose clamp meal tolerance test (MTT) in Japanese patients with type 2 diabetes mellitus. Fifteen [mean age: 53 years, fasting plasma (FPG) 7.7 mmol/L, HbA1c 7.1% (54 mmol/mol), body mass 26.8 kg/m2] underwent MTT clamp. Participants were given (450 kcal). Plasma measured at 0 (fasting), 30, 60, 120, 180 min. Serum C-peptide immunoreactivity (CPR) was (fasting; F-CPR) 120 Homeostasis model assessment of (HOMA-IR)...

10.1186/1475-2840-12-21 article EN cc-by Cardiovascular Diabetology 2013-01-01

Individual finger position and external grip forces were investigated while subjects held cylindrical objects from above using circular precision grips. Healthy females (n = 11) males 15) lifted of various weights (0.5, 1.0 2.0 kg), varied diameters (5.0, 7.5 10.0 cm) the 5-finger mode. The effects 4-, 3- 2-finger modes in also investigated. was nearly constant for all 5.0 cm. mean angular positions index, middle, ring little fingers relative to thumb 98 degrees, 145 181 236 respectively. At...

10.1080/00140139608964536 article EN Ergonomics 1996-09-01

The present study investigated the differential effects of emotions evoked by music on heart rate (HR) and its variability (HRV) during playing piano compared to those in persons listening same music. Thirteen elite pianists underwent experiments under expressive playing, nonexpressive listening, conditions. conditions produced significantly higher levels HR low-frequency component HRV, as well a lower level high-frequency component. A greater modulation these was also revealed for...

10.1111/j.1749-6632.2009.04788.x article EN Annals of the New York Academy of Sciences 2009-07-01

BarA of Streptomyces virginiae is a specific receptor protein for butanolides (VBs), member the butyrolactone autoregulators species. Sequencing around barA gene revealed two novel open reading frames: one upstream, barX, encoding homolog AfsA griseus and another downstream, barB. Northern (RNA) blot analysis S. demonstrated that addition VB during cultivation switched on expression An in vivo system lividans with use xylE reporter indicated conjunction controlled barB promoter. Furthermore,...

10.1128/jb.179.22.6986-6993.1997 article EN Journal of Bacteriology 1997-11-01

Using fast tapping tasks with each of the four fingers (single-finger tapping) and two used alternately (double-finger tapping), ability to make rapid movement by individual was compared between expert pianists nonmusician controls in both genders. Maximal pinch grasp forces were also measured assess strength whole hand, respectively. Movement ring little slower than that index middle controls. The slowness was, however, much less evident tasks. had smaller intertap interval variability for...

10.1123/mcj.9.1.23 article EN Motor Control 2005-01-01

Few studies have investigated the control of grip force when manipulating an object with extremely small mass using a precision grip, although some related information has been provided by conducted in unusual microgravity environment. Grip-load coordination was examined while healthy adults (N = 17) held moveable instrumented apparatus its changed between 6 g and 200 14 steps, surface set as either sandpaper or rayon. Additional measurements grip-force-dependent finger-surface contact area...

10.1371/journal.pone.0138506 article EN cc-by PLoS ONE 2015-09-16

The effect of gloves on the spatio-temporal characteristics prehensile forces during lifting and holding tasks was investigated. Participants (n = 10) lifted a force transducer equipped object (weight 0.29 N) with various types barehanded using two-fingered precision grip. Rubber surgical varied thicknesses (0.24, 0.61 1.02 mm) were worn to examine glove thickness rayon surface. It found that grip increased because participants employed higher safety margin above minimum required hold...

10.1080/001401399185018 article EN Ergonomics 1999-10-01

10.1007/bf00334416 article EN European Journal of Applied Physiology and Occupational Physiology 1996-06-01

The relationship between the key depression force on an upright piano and level of loudness a generated tone was examined when pianists hit force-sensor built-in with "struck" or "pressed" type touch. vertical displacement key, radiated sounds were also recorded. It found that for both types touch, simple exponential functions could adequately describe relation amplitude as well impulse tone. before maximum moment commonly amounted to above 80% total produced at below mezzo-forte. It,...

10.1121/1.2717493 article EN The Journal of the Acoustical Society of America 2007-05-01

Analysis of fermentation broth the entomopathogenic fungus Metarhizium anisopliae has led to isolation aurovertin D ( 1) and three new aurovertin-type metabolites, F 2), G 3), H 4). Their structures were determined on basis spectroscopic analyses chemical conversions.

10.1021/np070494e article EN Journal of Natural Products 2008-01-23
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