New heptamethine cyanine dyes with an alkylamino group at the central position were found to exhibit a large Stokes shift (>140 nm) and strong fluorescence. They suggested be new paradigm for excited-state intramolecular charge transfer (ICT). The configuration change of bridgehead amine accompanying ICT was investigated in different viscosity pH media.

Adsorbents widely utilized for environmental remediation, water purification, and gas storage have been usually reported to be either porous or crystalline materials. In this contribution, we report the synthesis of two covalent organic superphane cages, that are as nonporous amorphous superadsorbents aqueous iodine adsorption with record-breaking capability selectivity. static system, cages exhibit uptake capacity up 8.41 g g-1 in I2 solution 9.01 I3- (KI/I2) solution, respectively, even...

Herein we develop a new pillar[5]arene-mediated supramolecular polymerization strategy to control the assembly of dyes 4,7-di-2-thienyl-2,1,3-benzothiadiazole and 4,7-di-2-thienyl-2,1,3-benzoselenadiazole in solid state. The resulting polymeric structures drive dye aggregates state from parallel alignments highly ordered "head-to-tail" structures, which effectively suppresses excimer formation thus aggregation-caused quenching effects enhances solid-state emission efficiency by almost 1...

This paper mainly introduces the application of photothermal conversion MXenes in biomedical field, including therapy tumors, drug delivery, photoacoustic imaging, and antibacterial agents.

The in situ self-assembly of exogenous molecules is a powerful strategy for manipulating cellular behavior. However, the direct photochemically inert constituents into supramolecular nano-photosensitizers (PSs) within cancer cells precise photodynamic therapy (PDT) remains challenge. Herein, we developed glycosylated Aza-BODIPY compound (LMBP) capable self-assembling J-aggregate nanofibers cell membrane destruction and type I PDT. LMBP selectively entered human hepatocellular carcinoma HepG2...

Herein we report a novel host–guest complex single crystal material based on pillar[5]arene (P5) and laser dye trans-4-[p-(dimethylamino)styryl]-1-methylpyridinium iodide (DASP). Single structure characterization shows that two P5 molecules act as supramolecular nanocapsule for one isolated DASP molecule. This spatial confinement effectively restricts aggregation-caused quenching (ACQ) effects other nonradiative channels (e.g., twisted intramolecular charge transfer), leading to high...

Highly selective anion recognition and extraction is challenging yet critical for removal of pollutants from the environment effective recovery valuable chemicals low-content (at sub-ppm or ppb level) sources. In this paper, we detail gram-scale synthesis a superphane 2, an receptor that selectively binds ReO4−. Superphane 2 can extract perrhenate solid mixtures containing traces ReO4− (as low as 200 ppb) aqueous media with near 100% selectivity over large excesses competing anions....

A biscyclen molecular cabin, synthesized by connecting two cyclen macrocycles with four linkages, entraps a Li

Abstract The in situ self‐assembly of exogenous molecules is a powerful strategy for manipulating cellular behavior. However, the direct photochemically inert constituents into supramolecular nano‐photosensitizers (PSs) within cancer cells precise photodynamic therapy (PDT) remains challenge. Herein, we developed glycosylated Aza‐BODIPY compound ( LMBP ) capable self‐assembling J‐aggregate nanofibers cell membrane destruction and type I PDT. selectively entered human hepatocellular carcinoma...

Amid rising antibiotic resistance, the quest for advanced antibacterial agents to surpass microbial adaptation is paramount. This study introduces Pyrgos[ n ]cages ( = 1 4), pioneering multidecker cationic covalent organic cages engineered combat drug-resistant bacteria via a dual-targeting approach. Synthesized through successive photocatalytic bromination and cage-forming reactions, these architectures stand out their dense positive charge distribution, exceptional stability, substantial...

This work describes the one-pot synthesis of a superphane-based supramolecular receptor and its encapsulation water dimer.

Two kinds of AIE-active fluorescent organic nanoparticles were designed and constructed as anti-counterfeiting photoresponsive materials. One is (TPELs) based on a self-assembly strategy, which self-assembled from novel amphiphilic tetraphenylethylene (TPE) molecules decorated with lactose moiety different tags. The other polymeric (F-TPEs) derived the nanoprecipitation utilized pluronic copolymer F127 to encapsulate hydrophobic TPEs without lactosyl modifications. Upon UV light irradiation,...

Carcerands, special molecular constructs with enclosed interiors as a new phase of matter, have attracted immense interest because their unique structures, physicochemical properties, and potential applications in many aspects, e.g., targeted drug delivery. However, carcerands for imprisoning, inter alia, anions represent an unmet challenge. Herein, we report the design synthesis superphane-based carcerand 1, featuring up to 18 anion binding sites fully interior space. Carcerand 1 is found...

To study regulation in vivo of the promoter for neural cell adhesion molecule, N-CAM, we have used homologous recombination to insert bacterial lacZ gene between transcription and translation initiation sites N-CAM gene. This insertion disrupts places expression β-galactosidase under control promoter. Animals homozygous disrupted allele did not express mRNA or protein, but pattern heterozygous embryos was similar that wild-type animals. The homozygotes exhibited many morphological...

Superphanes, compounds in which the two benzene rings clamped parallel on top of each other by six bridges, have been attracting considerable interest because their structural beauty and symmetry. However, progress research superphane chemistry beyond has seriously hampered poor availability. Herein, we report facile scalable synthesis a collection superphanes with diversity unique photophysical properties, as well unusual host–guest behavior. A set secondary amine–linked are obtained via...

A newly synthesized multifunctional glycosylated and rhodamine-conjugated tetraphenylethylene (Lac-TR) achieved fluorescence self-reporting during photodynamic therapy induced pyroptosis under both normoxia hypoxia to kill HepG2 cells.

Type I photodynamic therapy (PDT) is well demonstrated to have low oxygen dependency. However, fully suppressing the risk of hypoxia-induced tumor metastasis during PDT remains a great challenge. In this study, tetra-lactosylated amphiphilic Aza-BODIPY glycocluster (TLBP) reported that self-assembles into supramolecular nanoglycocalyx on hepatoma cell membranes, serving as an artificial extracellular matrix (ECM) inhibit while facilitating efficient PDT. Molecular engineering demonstrates...

Macrocycle-to-macrocycle interconversions are of interest because they can allow access to a variety structures. However, reversible interconversion between different sized macrocycles remains challenging control. Herein, we report facile one-pot synthesis series self-assembled from readily prepared α,α'-linked oligopyrrolic dialdehydes and various alkyl diamines. The condensation pyridine-bridged dialdehyde 3 simple diamines proved independent solvent, always yielding the [2 + 2]...

Alzheimer’s disease (AD), an amyloid-related disease, seriously endangers the health of elderly individuals. According to current research, its main pathogenic factor is amyloid protein, which a kind fibrillar aggregate formed by noncovalent self-assembly proteins. Based on characteristics aggregation-induced emission (AIE), bislactosyl-decorated tetraphenylethylene (TPE) molecule TMNL (TPE + malononitrile lactose), bearing two substituents, was designed and synthesized in this work. The...