A5066582466- Pneumonia and Respiratory Infections
- Emergency and Acute Care Studies
- Nosocomial Infections in ICU
- Cancer survivorship and care
- Nutrition and Health in Aging
- Obstructive Sleep Apnea Research
- Antibiotic Use and Resistance
- Sepsis Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Muscle metabolism and nutrition
- Cannabis and Cannabinoid Research
- Bacterial Identification and Susceptibility Testing
- Healthcare and Venom Research
- Coffee research and impacts
- Mobile Health and mHealth Applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Coenzyme Q10 studies and effects
- Sleep and related disorders
- Prostate Cancer Treatment and Research
- Sensory Analysis and Statistical Methods
- Child Development and Digital Technology
- PI3K/AKT/mTOR signaling in cancer
- Atrial Fibrillation Management and Outcomes
- Cardiac Health and Mental Health
- Phonocardiography and Auscultation Techniques
Vanderbilt University Medical Center
2022-2025
University of Utah
2018-2022
University of Northern Colorado
2017-2019
University of California, San Francisco
2016-2018
University of Michigan
2014-2017
Christensen Fund
2016
Wayne State University
2012
Gentofte Hospital
2004
Alcon (United States)
2003
Stony Brook University
1991
Smartphones are increasingly integrated into everyday life, but frequency of use has not yet been objectively measured and compared to demographics, health information, in particular, sleep quality.The aim this study was characterize smartphone by measuring screen-time directly, determine factors that associated with increased screen-time, test the hypothesis is poor sleep.We performed a cross-sectional analysis subset 653 participants enrolled Health eHeart Study, an internet-based...
Use of empirical broad-spectrum antibiotics for pneumonia has increased owing to concern resistant organisms, including methicillin-resistant Staphylococcus aureus (MRSA). The association anti-MRSA therapy with outcomes among patients is unknown, even high-risk patients.
Non-ventilator-associated hospital-acquired pneumonia (NV-HAP) is a common and deadly infection. However, inconsistent surveillance methods unclear estimates of attributable mortality challenge prevention.
A series of contiguous 30-bp deletions were introduced into the regions upstream p19 and p40 promoters adeno-associated virus (AAV), effects these on induction AAV transcription by rep gene products was evaluated. novel complementation system devised for supplying wild-type Rep protein when mutations disrupted trans activation activity protein. Transcription from promoter eliminated upon deletion TATA sequence located between -4 -33 cap site. Deletions which removed sequences -34 to -123 bp...
Background— Ascertainment of hospitalizations is critical to assess quality care and the effectiveness adverse effects various therapies. Smartphones, mobile geolocators that are ubiquitous, have not been leveraged ascertain hospitalizations. Therefore, we evaluated use smartphone-based geofencing track Methods Results— Participants aged ≥18 years installed a application programmed geofence all hospitals using global positioning systems cell phone tower triangulation trigger questionnaire...
Surveillance of non-ventilator-associated hospital-acquired pneumonia (NV-HAP) is complicated by subjectivity and variability in diagnosing pneumonia. We compared a fully automatable surveillance definition using routine electronic health record data to manual determinations NV-HAP according criteria clinical diagnoses.We retrospectively applied an for all adults admitted Veterans' Affairs (VA) hospitals from January 1, 2015, November 30, 2020. randomly selected 250 hospitalizations meeting...
Introduction Patients with suspected bacterial infection frequently receive empiric, broad-spectrum antibiotics prior to pathogen identification due the time required for bacteria grow in culture. Direct-from-blood diagnostics identifying presence or absence of and/or resistance genes from whole blood samples within hours collection could enable earlier antibiotic optimisation patients have infections. However, few randomised trials evaluated effect using direct-from-blood testing on...
Abstract Lisano, JK, Smith, JD, Mathias, AB, Christensen, M, Smoak, P, Phillips, KT, Quinn, CJ, and Stewart, LK. Performance health-related characteristics of physically active men using marijuana. J Strength Cond Res 33(6): 1659–1669, 2019—The influence chronic marijuana use on the performance health individuals has yet to be fully elucidated. The purpose this study was explore pulmonary function, aerobic anaerobic fitness, strength, serum testosterone, cortisol, C-reactive protein (CRP),...
The control of chronic inflammation has emerged as a target for improving the health cancer survivors (CS).To examine differences in fitness and dietary characteristics CS when grouped by low vs. moderate to high serum C-reactive protein (CRP).CS (N = 26, mean age 68 ± 12 years) were evaluated body mass index (BMI), composition, cardiorespiratory fitness, intake, inflammatory (DII), CRP. Participants assigned one two groups based on CRP concentrations: (≤1 mg/L) (LWC; n 13) or (CRP > 1 (MHC;...
Asthma patients often have trouble gaining control of their disease because there is no optimal and reliable method to monitor progress. While spirometry in the clinic provides adequate information for diagnosis initial prescription, symptom journals peak flow meters used at home are not particularly helpful preventing asthma attacks. The 30-day hospital readmission rate following an attack 12%. Home spirometers available, however they can be prohibitively expensive. An affordable, accurate...
The 2019 American Thoracic Society/Infectious Diseases Society of America guidelines for community-acquired pneumonia (CAP) revised recommendations culturing and empiric broad-spectrum antibiotics. We simulated guideline adoption in Veterans Affairs (VA) inpatients.
Identification of pulmonary embolism (PE) across a cohort currently requires burdensome manual review. Previous approaches to automate capture PE diagnosis have either been too complex for widespread use or lacked external validation. We sought develop and validate the Regular Expression Aided Determination (READ-PE) algorithm, which uses portable text-matching approach identify in reports from computed tomography with angiography (CTA).
Introduction: Obstructive sleep apnea (OSA) is an established risk factor for atrial fibrillation (AF), but the mechanism unknown. Repeated hypopneas may induce mechanical stress OSA also causes poor which has been linked to other CVD. We sought determine if disruption independent of associated with AF. Methods: compared quality AF in three population-based cohorts. (1) In Health eHeart Study (HeH), internet-based cohort study, we self-reported frequent nighttime awakening (waking at night ≥...
Introduction: Reduced sleep quality, beyond that caused by obstructive apnea (OSA), has recently been associated with the development of obesity, hypertension, stroke, and death. While OSA shown to predict AF, it remains unknown if disturbances independent disease. Hypothesis: quality increases risk incident AF Methods: We performed a longitudinal analysis in sub-set participants Cardiovascular Health Study who were co-enrolled Sleep Heart Study. duration, efficiency, latency, architecture...