The diagnosis of cutaneous leishmaniasis (CL) might be difficult, in particular endemic areas where different species Leishmania can cause lesions very similar appearance and other skin diseases with clinical symptoms occur. Even today, the parasitological CL remains gold standard it is based on direct identification amastigotes microscopy smears and/or culture promastigotes from infected tissues. Although these techniques are highly specific, they not sensitive enough. objective this study...

Abstract Emerging reports show that coronavirus disease 2019 (COVID‐19) may lead to autoimmune and autoinflammatory diseases. However, COVID‐19 triggered systemic lupus erythematosus (SLE) has never been reported our knowledge. also associated cutaneous manifestations. Here we present a case of SLE with antiphospholipid antibody syndrome in previously healthy patient COVID‐19, who subsequently developped varicella‐like exanthem on the trunk. The resulted death patient. pathophysiological...

Autoimmune bullous diseases (AIBDs) are a heterogeneous group of characterized by cutaneous and mucosal vesicles, blisters, erosions. Several factors can trigger this disease, including vaccines; but entity remains very rare. We hypothesized that vaccination against coronavirus disease 2019 (COVID-19) could an immunological response in genetically predisposed individuals. report five cases new-onset autoimmune triggered the COVID-19 vaccine. Clinical histopathological examinations confirmed...

Skin metastases from endometrial adenocarcinoma, particularly cutaneous lymphangitis carcinomatosis, are rare. We present two cases of adenocarcinoma that recurred as lymphangitic carcinomatosis after presumed complete resection. Case 1 is a 71-year-old woman with history breast who developed painful erythematous lesions and verrucous plaque in the pubic area three months surgery for adenocarcinoma. A skin biopsy confirmed carcinomatous lymphangitis, she died four later. 2 56-year-old stage...

Waardenburg syndrome (WS) is an autosomal dominant disorder caused by mutations in genes involved the development of neural crest cells, affecting pigmentation, hearing, and craniofacial structures. This article presents a case 2-year-old girl diagnosed with WS type 1, who exhibited key characteristics such as white forelock, heterochromia iridum, dystopia canthorum, without hearing loss or other systemic abnormalities. The absence impairment does not exclude diagnosis this highlights...

Nail melanoma is rare and has a poor prognosis. It represents between 0.18 2.8% of all cutaneous melanomas. Amputation usually performed for invasive nail melanoma, but not melanomas invade or attach to the distal phalanx. Our aim was report case 56-year-old patient with history manipulated melanonychial band right big toe since 5 years presenting bone infiltration .Our illustrates consequences late diagnosis which led deep progression invasion by malignant melanocytes.

Cutaneous leishmaniasis (CL) is commonly seen in pediatric patients endemic areas, including Morocco. This retrospective, single center study details 64 confirmed cases of CL treated with oral clarithromycin 15 mg/kg/day for 10 days per month, a total three months. Lesions improved 96.8% and the treatment was well tolerated. Clarithromycin seems safe effective alternative to intralesional injections meglumine antimoniate.

Tinea capitis is a fungal infection affecting school-age children in Morocco. A study at Ibn Rochd University Hospital Casablanca found 267 patients, mostly males (69.6%), with an average age of 7.24 years. Microsporum. canis was the most prevalent pathogen (56.5%), followed by Trichophyton. violaceum (18.3%). The indicates that Microsporum emerging as leading cause, linked to changes animal populations and pet ownership. Systematic mycological exams before treatment are crucial.

A 60-year-old female developed symptoms of eosinophilic fasciitis 10 days after receiving the second dose COVID-19 vaccine, characterized by sclerotic and hyperpigmented lesions, hypereosinophilia, positive antinuclear antibodies. The diagnosis was confirmed through deep skin biopsy MRI, treatment with prednisone methotrexate showed great improvement. This case highlights potential for to be triggered although exact mechanisms relationship remain unclear

Sweet syndrome is a rare inflammatory dermatosis in infants, characterized by atypical symptoms. We report case of 9-month-old infant presented with fever and migratory ascending erythematous plaques on the left foot leg. Laboratory results histology confirmed without underlying malignancies or infections. Treatment ibuprofen topical corticosteroids led to significant improvement. infancy often linked infections but can indicate serious issues, generally has good prognosis corticosteroids.

The global rollout of COVID-19 vaccines has been a significant step in controlling the SARS-CoV-2 pandemic. While have proven to be generally safe, adverse reactions, including both local and systemic effects, observed. Cutaneous manifestations, though rare, reported some instances. We report case 67-year-old male who developed pruritic erythematous-to-violaceous papules plaques three days after receiving second dose vaccine. lesions were found on right inner thigh, forearms, trunk, neck....

Infantile hemangiomas (IHs) are the most prevalent benign vascular tumors in pediatric populations, with an incidence of approximately 5 to 10% infants under one year age. IHs otorhinolaryngological (ENT) region present significant diagnostic and therapeutic challenges due their potential impact on critical functions such as respiration phonation. This study provides a comprehensive analysis epidemiological clinical characteristics, modalities, outcomes ENT region. Despite advancements,...

Neutrophilic dermatosis of the dorsum hands (NDDH) is a rare inflammatory condition that belongs to spectrum neutrophilic dermatoses and frequently associated with systemic diseases, particularly hematologic malignancies. We report case an 80-year-old woman NDDH revealing underlying myelodysplastic syndrome, later complicated by panniculitis face. Cutaneous lesions can often be misdiagnosed due their variable sometimes atypical presentation, leading delays in appropriate management. The...

Melkersson-Rosenthal syndrome is a rare condition classically characterized by orofacial edema, furrowed tongue, and peripheral facial paralysis. Miescher's cheilitis or granulomatous macrocheilitis represents the monosymptomatic form of this syndrome. It in childhood, more common young adults, its etiopathogenesis remains poorly understood. We report pediatric case treated with clarithromycin.

Wells' syndrome (WS), or eosinophilic cellulitis, is a rare inflammatory dermatosis with variety of clinical presentations. It typically manifests recurrent pruritic erythematous plaques and edematous swellings, which can be mistaken for other conditions, such as erysipelas angioedema. We report an unusual presentation WS localized on the face 60-year-old male history facial plaques, mistakenly treated After extensive evaluation, diagnosis smoldering multiple myeloma was revealed underlying...

Carvajal syndrome is a rare hereditary disease, stemming from recessive mutation in the desmoplakin gene, crucial for cell adhesion. Its hallmark features include woolly hair, palmoplantar keratoderma, and dilated cardiomyopathy, primarily affecting left ventricle of heart 1.We report case an 18-month-old infant early diagnosed with revealed by dermatological symptoms confirmed genetic testing.

Lucie Frey Syndrome, or "gustatory sweating," is a rare autonomic neuropathy caused by aberrant parasympathetic reinnervation following nerve damage. While commonly associated with traumatic surgical etiologies, infectious causes such as herpes zoster are exceptionally in pediatric cases. We report the case of 3-year-old female who developed unilateral erythema and focal hyperhidrosis on right hemiface.