A5101919045- Impact of Technology on Adolescents
- Functional Brain Connectivity Studies
- Child Development and Digital Technology
- Tryptophan and brain disorders
- Treatment of Major Depression
- Plant Molecular Biology Research
- Mind wandering and attention
- Neuroscience and Neuropharmacology Research
- Cultural and Historical Studies
- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Photosynthetic Processes and Mechanisms
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Plant Reproductive Biology
- Mental Health Research Topics
- EEG and Brain-Computer Interfaces
- Nutrition, Health and Food Behavior
- Carbon and Quantum Dots Applications
- Digital Mental Health Interventions
- Diverse Approaches in Healthcare and Education Studies
- Transcranial Magnetic Stimulation Studies
- Obsessive-Compulsive Spectrum Disorders
- Lipid Membrane Structure and Behavior
- Air Quality and Health Impacts
- Inflammasome and immune disorders
Massachusetts Institute of Technology
2019-2025
Samsung Medical Center
2007-2025
Sungkyunkwan University
2006-2025
Keimyung University
2023-2025
Korea University
2014-2023
Korea Research Institute of Bioscience and Biotechnology
2021-2023
Korea University of Science and Technology
2021-2023
Boramae Medical Center
2016-2022
Dongguk University
2017-2021
National Institute of Mental Health
2016-2018
Gibberellins (GAs) are a class of phytohormones, important for plant growth, and very difficult to distinguish because their similarity in chemical structures. Herein, we develop the first nanosensors GAs by designing engineering polymer-wrapped single-walled carbon nanotubes (SWNTs) with unique corona phases that selectively bind bioactive GAs, GA3 GA4, triggering near-infrared (NIR) fluorescence intensity changes. Using new coupled Raman/NIR fluorimeter enables self-referencing nanosensor...
Abstract Arsenic is a highly toxic heavy‐metal pollutant which poses significant health risk to humans and other ecosystems. In this work, the natural ability of wild‐type plants pre‐concentrate extract arsenic from belowground environment exploited engineer plant nanobionic sensors for real‐time detection. Near‐infrared fluorescent nanosensors are specifically designed sensitive selective detection arsenite. These optical embedded in tissues non‐destructively access monitor internal...
Abstract Plants are naturally abundant and display high sensitivity to ecological factors thrive in diverse environmental conditions. As sessile organisms, they have evolved complex, internal, interplant signaling pathways with distinct structures promptly adjust the constantly changing environment. In past five years, unique ways which exchange information function environment inspired an emerging field of plant nanobionics, describes interface between living plants nanotechnology impart...
Corona phase molecular recognition (CoPhMoRe) is a technique whereby an external, adsorbed around colloidal nanoparticle selected such that its conformation or interaction recognizes specific target analyte. In this work, we employ high-throughput screening of library poly(ethylene glycol) (PEG)-conjugated lipids onto near-infrared fluorescent single-walled carbon nanotubes to discover corona selective for insulin. We find C16–PEG(2000 Da)–ceramide causes 62% intensity decrease the (10,2)...
The identification of the predictive factors and biological markers associated with treatment-related changes in symptoms Internet gaming disorder (IGD) may provide a better understanding pathophysiology underlying this condition. Thus, present study aimed to identify neurophysiological symptom IGD patients that predict improvements following outpatient treatment pharmacotherapy. included 20 (mean age: 22.71 ± 5.47 years) 29 healthy control subjects 23.97 4.36 years); all completed 6-month...
Synthetic auxins such as 1-naphthalene acetic acid (NAA) and 2,4-dichlorophenoxyacetic (2,4-D) have been extensively used in plant tissue cultures herbicides because they are chemically more stable potent than most endogenous auxins. A tool for rapid planta detection of these compounds will enhance our knowledge about hormone distribution signaling facilitate efficient usage synthetic agriculture. In this work, we show the development real-time nondestructive NAA 2,4-D nanosensors based on...
The Interleukin-6 (IL-6) family of cytokines regulates inflammation and plays important roles in numerous biochemical pathways. Typically, cytokine levels are measured using enzyme-linked immunosorbent assay (ELISA) or western blot. However, these techniques usually require substantial processing time, cost, machinery, specialist training. Understanding the fundamental molecular recognition mechanism with synthetic substrates is key to developing new biomedical technologies such as assays,...
As the male gametophyte of flowering plants, pollen grains are ideal targets for introduction transgenes plant genetic engineering and crop improvement. However, difficulty delivering exogenous DNA into grains, because chemically inert cell walls, has hindered their widespread application in biotechnology. Herein, we report a new class nanocarriers, composed imidazolium (IM)-functionalized single-walled carbon nanotubes (SWNTs), which can efficiently traverse past barriers deliver genes...
Abstract This study investigated attentional bias toward game-related cues in Internet gaming disorder (IGD) using electrophysiological markers of late positive potential (LPP) and identifying the sources LPP. In addition, association between LPP decision-making ability was investigated. The IGD ( n = 40) healthy control (HC; 39) participants viewed a series neutral pictures, while their event-related potentials (ERPs) were recorded. LPPs calculated as mean amplitudes 400 700 ms at...
Although internet gaming disorder (IGD) and obsessive-compulsive (OCD) represent opposite ends of the impulsivity compulsivity dimensions, two disorders share common neurocognitive deficits in response inhibition. However, similarities differences neurophysiological features altered inhibition between IGD OCD have not been investigated sufficiently. In total, 27 patients with IGD, 24 OCD, 26 healthy control (HC) subjects participated a Go/NoGo task electroencephalographic recordings. N2-P3...
Abstract Internet gaming disorder (IGD) leading to serious impairments in cognitive, psychological and social functions has gradually been increasing. However, very few studies conducted date have addressed issues related the event-related potential (ERP) patterns IGD. Identifying neurobiological characteristics of IGD is important elucidate pathophysiology this condition. P300 a useful ERP component for investigating electrophysiological features brain. The aims present study were...
Internet gaming disorder (IGD) is a newly identified potential addiction associated with compulsive internet-game playing behavior and attentional bias toward online gaming- related cues. Attentional addiction-related cues the core feature of that craving, but pathophysiology in IGD not well-understood, such as its relationship to compulsivity. In this study, we used electrophysiological marker late positive (LPP) compare obsessive (OCD). Twenty patients IGD, 20 OCD, 23 healthy control (HC)...
Minkyung Park, Young-Lai Cho, Yumin Choi, Jeong-Ki Min, Young-Jun Sung-Jin Yoon, Dae-Soo Kim, Mi-Young Son, Su Wol Chung, Heedoo Lee & Seon-Jin Lee. BMB Reports -0001;0:. https://doi.org/10.5483/BMBRep.2022-0139
We introduce a general and versatile methodology that allows facile incorporation of the functional components with completely different chemistry hydrophilic/hydrophobic properties within nanocomposite films, furthermore combine number distinctive advantages traditional electrostatic layer-by-layer (LbL) assembly in aqueous media covalent LbL nonpolar media. Our approach, amphiphilic assembly, is based on high affinity between sulfonic (or phosphonic) acid-functionalized materials...
The corona phase—the adsorbed layer of polymer, surfactant, or stabilizer molecules around a nanoparticle—is typically utilized to disperse nanoparticles into solution solid phase. However, this phase also controls molecular access the nanoparticle surface, property important for catalytic activity and sensor applications. Unfortunately, few methods can directly probe structure phase, which is subcategorized as either hard, immobile soft, transient in exchange with components bulk solution....
This study assessed the effects of transcranial direct current stimulation (tDCS) on cue reactivity and craving for game-related cues using event-related potentials (ERPs) in internet gaming disorder (IGD) patients. At baseline, a series neutral pictures were shown to both IGD healthy controls (HCs) while ERPs recorded. Late positive (LPP) used investigate reactivity. During intervention, patients received 10 sessions (two sessions/day 5 consecutive days, 2 mA 20 min/session) tDCS left...
The increased prevalence of Internet Gaming Disorder (IGD) and the inclusion IGD in DSM-5 ICD-11 emphasizes importance measuring describing symptoms. We examined psychometric properties Diagnostic Interview for Addiction (DIA), a semi-structured diagnostic interview tool IGD, verified application DIA clinical practice Korean adolescents. is conducted manner that interviews both adolescents their caregivers, each item has standardized representative question various examples. It consists 10...
The ability to detect and correct errors is a critical aspect of human cognition. Neuronal dysfunction in error processing has been reported addictive disorders. aim this study was investigate neural systems underlying using event-related potentials (ERPs) current source localization as well neurocognitive executive function tests patients with Internet gaming disorder (IGD). A total 68 individuals (34 IGD 34 healthy controls [HCs]) were included, two ERP components, error-related negativity...