This study showed that impoverished Nigerian children at risk for cancrum oris (noma) had significantly reduced plasma concentrations of zinc (< 10.8 micromol/L), retinol 1.05 ascorbate 11 and the essential amino acids, with prominently increased saliva levels free cortisol, compared their healthy counterparts. The nutrient deficiencies, in concert previously reported widespread viral infections (measles, herpesviruses) children, would impair oral mucosal immunity. We postulate, subject...

Summary: The need to identify high risk features of atherosclerotic cardiovascular disease (ASCVD) in indigenous Black African adolescents is urgent now more than ever. In ASCVD, an imunoinflammatory pathology, plaques lipid origin progressively gather wall human blood vessels and partially or completely obscure the lumen.

Introduction This study aimed to determine whether triglyceride/high-density lipoprotein cholesterol (TG/HDL-c) ratio, which has been shown be an innovative proxy marker of atherogenic indicator in the human plasma, and metabolic syndrome (MetS) insulin resistance (IR), can predict systolic hypertension (SHT), diastolic (DHT), diabetic fasting plasma glucose (dFPG), hypertriglyceridemia (HTG), hypercholesterolemia (HCHOL) low high-density lipoprotein-cholesterol (HDL-c) high low-density...

A total of 446 infants in the first 6 months life who presented at an urban children's hospital with complaints any illness whatsoever were recruited into a study aim determining contribution malaria to infant morbidity malaria-endemic area Nigeria. Sixty-eight their month and 79, 77, 61, 97, 64 second, third, fourth, fifth sixth life, respectively. Overall, 107 (24.0%) clinically diagnosed as having malaria. This included 3 12 15 17 33 fifth, 27 (4.4, 15.2, 19.5, 27.9, 34.0, 42.1%,...

Brain monoamine levels may underlie aspects of the cerebral component falciparum malaria. Since circulating amino acids are precursors for brain synthesis, we measured them in malaria patients and controls. Malaria elicited significantly elevated plasma phenylalanine, particularly comatose patients, with Tyr/Phe (%) ratio reduced from 83.3 controls to 39.5 infected children, suggesting an impaired phenylalanine hydroxylase enzyme system infection. increased apparent K(m) Trp, Tyr His, no...

Contraceptives are advocated to be used against unwanted pregnancy and sexually transmitted diseases as unsafe abortion contributes high maternal mortality in Nigeria while pregnancies have terminated the educational development of many females.This questionnaire-based survey aimed describe knowledge, nonuse, use various contraceptive methods among women different child-bearing age groups rural Lagos, Nigeria.Between 2012 2013, 816 females communities within Lagos State were surveyed for...

Among the strategies being tested to improve prompt and appropriate treatment of febrile illness, especially malaria, in young children is prepackaging antimalarial drugs easy use daily dosages. A TDR-sponsored study three rural communities southern Nigeria a delivery system for prepackaged chloroquine cotrimoxazole aged 6 months years. variety distributors were trained including village health workers (VHWs), patent medicine vendors (PMVs), clinic staff. These also performed community...

Journal Article Effect of chlorpheniramine on the pharmacokinetics and response to chloroquine Nigerian children with falciparum malaria Get access C.A. Okonkwo, Okonkwo 1Nigerian Institute Medical Research, Yaba, Lagos, Nigeria Search for other works by this author on: Oxford Academic PubMed Google Scholar H.A.B. Coker, Coker 2School Pharmacy, College Medicine University P.U. Agomo, Agomo ⋆ ⋆Address correspondence: Dr P. U. Biochemistry Division, M. B. 2013, Nigeria. J.A. Ogunbanwo,...

To determine the hourly density of vector mosquitoes in coastal Nigeria, compare seasonal human-biting and sporozoite rates density, locate breeding sites mosquitoes, larval population at sites.Indoor outdoor a Nigerian community were caught during early late wet seasons harmattan period, time dusty wind from Sahara on western coast Africa. Larvae collected various locations study period. The physically characterized their salivary glands dissected for rate. was calculated. Human-biting rate...

Background Endometriosis is a debilitating disease in women of child-bearing age. Objective To describe the pattern presentation, stage endometriosis and biophysical profile patients with endometriosis. Method A retrospective study 61 consecutive infertile between June 2003 November 2014. Results The means (±SD) age (years) body mass index (BMI) (kg/m 2 ) were 34.1 (4.3) 25.8 (5.0), respectively. relatively high percentage (43, 70.5%) range 31-40 years; had normal BMI (27, 44.3%);...

AbstractThe efficacy of amodiaquine against Plasmodium falciparum malaria was assessed in an area confirmed chloroquine resistance the cool, north-central plateau Nigeria, using a 14-day protocol. The patients were all children aged <5 years age. drug proved highly efficacious, giving cure 'rate' 100% on day 14 and mean fever- parasite-clearance times 1.11 3.11 days, respectively. It also well tolerated. Following treatment, packed-cell volumes (PCV) generally increased (65% patients) but...

Introduction: Men without sperm (azoospermic) make up about 15% of all infertile men in reproductive age fatherhood. Male infertility is a health and social problem many communities. Subjects Methods: This retrospective study was carried from 2010 to 2015. Initially, 907 were included the among whom 109 (12.02%), 346 (38.15%) 452 (49.83%) azoospermic, oligospermic normospermic, respectively. only investigated association between age, BMI, semen volume, liquefaction time pus cells...

Background: Malaria parasitemia during pregnancy is a most important public health problem to governments and individuals in malaria endemic regions of the world.Moderate or severe anemia may be associated with heavy parasitic infestation.However, not only cause pregnant women developing countries.Objective: To determine prevalence different trimester, gravida age group Study design: A cross-sectional study that recruited 113 who were screened for parasites anemia. Setting:The was conducted...

_Introduction:_ Metabolic syndrome (MetS) is a group of risk factors which together increase the chance heart disease, stroke, and type 2 diabetes. In MetS, especially among overweight obese people, blood pressure glucose are elevated, excess body fat accumulates abdominally, there dyslipidemia (notably low level high-density lipoprotein (HDL) cholesterol high triglycerides). There scarcity data available on MetS secondary school children in Lagos, Nigeria. _Objective: _To determine...

Context: Bacterial vaginosis has been prospectively linked to various adverse reproductive and pregnancy related events. Objective: To determine the prevalence of bacteria among first time antenatal clinic attendees in Northwest Nigeria. Study design, setting subjects: A Cross sectional study conducted at Antenatal Ahmadu Bello University Teaching Hospital, Zaria, north-west total 228 consecutive booking clients were enrolled from April June, 2008. Main outcome measures: Presence least three...

Background: Male infertility is approaching an epidemic proportion. Almost 50% of all cases may be associated with a male factor. The diagnostic usefulness sperm DNA integrity now accessible as additional tool to Seminal Fluid Analysis. Objective: To assess fragmentation index (SDFI) in and its relationship obesity, alcohol consumption cigarette smoking among infertile Nigerians. Patients Methods: who presented for at three health facilities Nordica Fertility Center Lagos, Asaba Abuja cities...

The dilemma and psycho–social challenges of un–intentional infertility in sub–saharan Africa

Objective: The objective of this study was to examine patterns douching practices and their association vaginal infection among Hausa-Fulani pregnant women in Zaria, Northwest Nigeria. Study design: This health facility-based a descriptive cross-sectional investigation, with laboratory analysis for bacterial vaginosis other flora. Results: Of 220 participants, 85.5% consented regular practices. Commonly identified methods were using hand insert plain water (80.0%), insertion toilet soap...