A5056418892- Nosocomial Infections in ICU
- Respiratory Support and Mechanisms
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Antibiotic Use and Resistance
- Sepsis Diagnosis and Treatment
- Influenza Virus Research Studies
- Asthma and respiratory diseases
- Emergency and Acute Care Studies
- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Central Venous Catheters and Hemodialysis
- Dysphagia Assessment and Management
- Reproductive tract infections research
- Cervical Cancer and HPV Research
- Neuroendocrine Tumor Research Advances
- Patient Satisfaction in Healthcare
- Animal Disease Management and Epidemiology
- School Health and Nursing Education
- Healthcare Systems and Practices
- Congenital Diaphragmatic Hernia Studies
- IL-33, ST2, and ILC Pathways
Siriraj Hospital
1999-2024
Mahidol University
2002-2024
National Institute of Health
2022
Harborview Medical Center
2004
University of Washington
2004
Most international guidelines recommend empirical therapy for community-acquired pneumonia (CAP) to be based on site of care. Some patients with severe CAP are managed in general wards because limited intensive care unit (ICU) bed or unrecognition the severity. Appropriate initial antibiotic treatment outside ICU has not yet been established. This study aimed determine prevalence and impact selection outcomes who were admitted managing wards.This prospective observational included...
We explored the self-reported antibiotic stewardship (AS), and infection prevention control (IPC) activities in intensive care units (ICUs) of different income settings. A cross-sectional study was conducted using an online questionnaire to collect data about IPC AS measures participating ICUs. The participants were Infectious Diseases-International Research Initiative (IDI-IR) members, committed as per their institutional agreement form. analyzed responses from 57 ICUs 24 countries...
Inhaled corticosteroids (ICS) represent an alternative treatment option to systemic (SCS) in the of asthma and chronic obstructive pulmonary disease (COPD); however, detailed clinical guidance on use nebulized ICS, such as budesonide, management COPD remains scarce. To review literature develop Delphi consensus statements ICS for adults. An expert panel 13 respiratory physicians, comprising pulmonologists (n = 9), allergists 1), emergency department consultants 3) from tertiary medical...
Abstract Background Respiratory syncytial virus (RSV) is an increasingly common cause of respiratory illness in adult non‐immunocompromised patients. Oral ribavirin was reported to improve outcomes RSV infection immunocompromised This study aimed determine the patients hospitalized with RSV‐associated acute illnesses (RSV‐ARI), factors independently associated and effect oral treatment. Methods retrospective, observational cohort included 175 adults admitted hospital virologically confirmed...
Abstract The objective of this study was to evaluate the value bronchoalveolar lavage (BAL) and postbronchoscopic sputum cytology in diagnosing peripheral lung cancer. We performed a prospective 55 patients with lesions on chest radiographs who were suspected having cancer had non‐endoscopically visible fiberoptic bronchoscopy. sequence procedures all cases BAL transbronchial forceps biopsy. final diagnosis these primary 30 patients, metatastic five benign diseases 20. In group, positive for...
Background We wanted to determine the impact of combined Clinical Pulmonary Infection Score (CPIS) and a spot serum procalcitonin (PCT)-guided protocol shorten duration antibiotic treatment in patients with ventilator-associated pneumonia (VAP), mainly caused by nonfermentative gram-negative bacilli (NF-GNB). Methods Patients VAP who received appropriate antibiotics for 7 days, temperature ⩽ 37.8°C, without shock, CPIS 6 were allocated PCT group or conventional according treating physicians’...
We aimed to determine the prevalence of bacterial coinfection (CoBact) and superinfection (SuperBact), causative pathogens, initial antibiotic-prescribing practice, associated clinical outcomes hospitalized patients with respiratory syncytial virus-associated acute illness (RSV-ARI). This retrospective study included 175 adults RSV-ARI, virologically confirmed via RT-PCR, during period 2014-2019. Thirty (17.1%) had CoBact, 18 (10.3%) SuperBact. The independent factors CoBact were invasive...
Objective: The aim of this study was to assess the frequency and type adverse reactions following influenza vaccination its effects on lung function, dyspnoeic symptoms, exercise capacity, clinical acute respiratory illness (ARI) in patients with COPD, relationship these degree airflow obstruction. Methodology: A stratified, randomized, double‐blind placebo‐controlled conducted over an 18‐month period at a single university hospital. In total, 125 COPD were randomized vaccine group (62 who...
Transforming growth factor-β-associated kinase 1 (TAK1) mediates non-canonical TGF-β signalling by promoting adhesive, migratory, proliferative and contractile responses of fibroblasts to TGF-β1. However, TAK1 expression status in asthmatic patients with or without fixed airway obstruction (FAO) is unknown.A total 60 adult asthmatics FAO were recruited compared 43 those (nFAO). TGF-β1 concentrations, phosphorylated (p-TAK1) levels determined sputum supernatants, cytospin, whole cell lysate...
Archival serum samples from elderly individuals with underlying chronic obstructive pulmonary disease (COPD) who were enrolled in a double-blind case-control study of seasonal influenza vaccine efficacy assayed for cross-neutralizing antibody formation to avian A (H5N1) virus. Of 118 samples, 58 collected vaccinees (mean age 68.5 y), and 60 placebo controls 68.4 y) received vitamin B injections. Blood before at 1 mo after vaccination all subjects; addition, longitudinal follow-up period y...
Objectives: The present study was conducted to determine the degree of agreement between interpretation spirometry using a specified percentage predicted value (SPC) and fifth percentile (FPC) as cut off normal abnormal. Methodology: Spirometric values were collected for 1754 subjects attending respiratory service at Siriraj Hospital February 2000 April 2001. These included forced vital capacity (FVC), expiratory volume in 1 s (FEV ), FEV /FVC, maximal mid‐expiratory flow (FEF 25–75% ) peak...