A5075478681- Bone and Dental Protein Studies
- dental development and anomalies
- Oral and Maxillofacial Pathology
- Bone Metabolism and Diseases
- Periodontal Regeneration and Treatments
- RNA regulation and disease
- Molecular Biology Techniques and Applications
- Oral microbiology and periodontitis research
- Digestive system and related health
- Dental materials and restorations
- RNA modifications and cancer
- Pleistocene-Era Hominins and Archaeology
- Bone Tumor Diagnosis and Treatments
- Endodontics and Root Canal Treatments
- Dental Erosion and Treatment
- Bone health and treatments
Université Paris Cité
2015-2022
Inserm
2015-2022
Sorbonne Université
2015-2022
Centre de Recherche des Cordeliers
2015-2022
Craniofacial and jaw bones have unique physiological specificities when compared to axial appendicular bones. However, the molecular profile of osteoblast (OB) remains incomplete. The present study aimed decipher bone site-specific profiles transcription factors (TFs) expressed in OBs vivo. Using RNA sequencing analysis, we mapped transcriptome confirmed from 2 different skeletal sites: mandible (Md) tibia (Tb). OB contains 709 TF genes: 608 are similarly Md-OB Tb-OB, referred as "OB-core";...
Background and objective:FAM20A gene mutations result in enamel renal syndrome (ERS) associated with amelogenesis imperfecta (AI), nephrocalcinosis, gingival fibromatosis, impaired tooth eruption. FAM20A would control the phosphorylation of peptides thus mineralization. Here, we characterized structure chemical composition unerupted from ERS patients healthy subjects. Methods: Tooth sections were analyzed by Scanning Electron Microscopy (SEM), Energy Dispersive Spectroscopy (EDS), X-Ray...
Dentin differs in composition and morphology depending on its anatomical location circumstances of formation (1). Circumpulpal dentinogenesis patterns, either a physiological or reparative c...
L’émail dentaire est un matériau modèle pour appliquer une approche physicochimique. Des pathologies ou l’environnement peuvent induire destruction, dégradation des malformations amélaires. Contrairement à la plupart autres tissus biologiques minéralisés, l’émail incapable de se régénérer naturellement. Comprendre les mécanismes l'émail présente intérêt scientifique et économique. Cette revue propose donner aperçu bibliographique travaux dix dernières années. Les études par techniques...