A5084746931- Field-Flow Fractionation Techniques
- Proteins in Food Systems
- Food composition and properties
- RNA and protein synthesis mechanisms
- Polysaccharides Composition and Applications
- thermodynamics and calorimetric analyses
- Chemical and Physical Properties in Aqueous Solutions
- Hip and Femur Fractures
- Toxin Mechanisms and Immunotoxins
- Microbial Metabolites in Food Biotechnology
- Phase Equilibria and Thermodynamics
- Hip disorders and treatments
- Pickering emulsions and particle stabilization
- Chemical Synthesis and Analysis
- Reproductive Biology and Fertility
- Polymer Surface Interaction Studies
- Fluorine in Organic Chemistry
- Fluid Dynamics and Mixing
- Orthopaedic implants and arthroplasty
- Bacterial Genetics and Biotechnology
- Sperm and Testicular Function
- Chemical Synthesis and Reactions
- Reproductive Health and Technologies
- Protein purification and stability
- Surfactants and Colloidal Systems
Lund University
2016-2025
Umeå University
2024
Getinge (Sweden)
2021
Faculty (United Kingdom)
2019
Engineering (Italy)
2019
Sahlgrenska University Hospital
1992-2017
Stockholm University
1986-2014
Technical University of Denmark
2008
University of Copenhagen
2008
AstraZeneca (Sweden)
2008
The analysis of aggregates therapeutic proteins is crucial in order to ensure efficacy and patient safety. Typically, the performed finished formulation that are not present. An important question is, however, what happens proteins, with regard oligomerization aggregation, after they have been administrated (i.e., blood). In this paper, separation whole blood, plasma, serum shown using asymmetric flow field-flow fractionation (AF4) a minimum sample pre-treatment. Furthermore, size...
The adsorption of starch that had been hydrophobically modified with octenyl succinate anhydride (OSA) at the oil/water interface during emulsification was studied. samples were waxy barley origin and varied in molar mass degree substitution (DS). particle size emulsions measured adsorbed amount determined through serum depletion. results show is governed by relationship between interfacial area OSA-starch concentration. surface load can some cases become very high, reaching 16 mg/m2. occurs...
The behavior of antioxidants in emulsions is influenced by several factors such as pH and emulsifier type. This study aimed to evaluate the interaction between selected food emulsifiers, phenolic compounds, iron, their effect on oxidative stability n-3 polyunsaturated lipids a 10% oil-in-water emulsion. emulsifiers tested were Tween 80 Citrem, compounds naringenin, rutin, caffeic acid, coumaric acid. Lipid oxidation was evaluated at all levels, that is, formation radicals (ESR),...
This study reveals specific ion effects on particle formation during peristaltic pumping of a monoclonal Antibody (Antibody A). For this purpose, three anions in the direct Hofmeister series were selected, ranging from kosmotropic SO42- to more neutral Cl- and chaotropic SCN-. Protein is described primarily as surface-driven mechanism. Therefore, effect was hypothesised affect with smallest amount protein adsorbing least particles formed presence SCN-, followed by highest SO42-. The...
Epidemiological studies suggest that foods rich in flavonoids might reduce the risk of cardiovascular disease and cancer. The objective present study was to investigate effect green tea extract (GTE) used as a food antioxidant on markers oxidative status after dietary depletion catechins. designed 2×3 weeks blinded human cross-over intervention (eight smokers, eight non-smokers) with GTE corresponding daily intake 18·6 mg catechins/d. incorporated into meat patties consumed strictly...
In this paper, we study the mechanical degradation and changes in conformation of a branched ultrahigh molar mass biomacromolecule, hydrophobically modified starch, as caused by high-pressure homogenization. The characterization was performed with asymmetrical flow field-flow fractionation (AsFlFFF) multiangle light scattering (MALS) refractive index detection. starch which had been chemically octenyl succinate anhydride (OSA) proved to be very large polydisperse. Upon homogenization, rms...
In this paper, we studied the adsorption at emulsion droplets of potato starch, which was hydrophobically modified with octenyl succinate anhydride (OSA), a surface active macromolecule containing ultrahigh molar mass components. The results show that substance works as an efficient emulsifier and it can in some cases generate high loads (10 mg/m2). be explained interplay between kinetic factors during formation physical-chemical properties such degree substitution, mass, radius. turbulent...
In the present study, we applied a regularized inversion method to extract particle size, magnetic moment and relaxation-time distribution of nanoparticles from small-angle x-ray scattering (SAXS), DC magnetization (DCM) AC susceptibility (ACS) measurements. For measurements particles were colloidally dispersed in water. At first approximation could be assumed spherically shaped homogeneously magnetized single-domain particles. As model functions for inversion, used form factor sphere...
In eight undisplaced intracapsular fractures of the femoral neck, an hematoma was diagnosed by computed tomography. 99mTc-MDP scintimetry revealed markedly reduced or absent blood supply to head femur. The pressure 23 (2.7-43) kPa with hip in neutral position. Following aspiration 12 (0.5-36) ml blood, zero, and postaspiration restitution head. Hip joint tamponade these patients has caused ischemia, reversible aspiration.
Casein (CN) micelles are naturally occurring colloidal protein aggregates present in a dispersed state milk. In this paper we aim to obtain detailed description of physicochemical properties CN over the entire size distribution using asymmetrical flow field-flow fractionation (AsFlFFF) connected multiangle light scattering (MALS) and refractive index (RI) detection. Conclusions drawn on level regarding shape conformation by comparison with models particles. By AsFlFFF-MALS-RI, it is...
An extraction method for mixed-linkage β-glucan from oat and barley was developed in order to minimize the effect of on structure. β-Glucan were characterized terms molecular size molar mass distributions using asymmetric flow field-flow fractionation (AF4) coupled multiangle light scattering (MALS), differential refractive index (dRI) fluorescence (FL) detection. The carbohydrate composition extracts analysed polysaccharide analysis by gel electrophoresis (PACE) high-performance...
Abstract The structural and magnetic properties of multi-core particles were determined by numerical inversion small angle scattering isothermal magnetisation data. investigated consist iron oxide nanoparticle cores (9 nm) embedded in poly(styrene) spheres (160 nm). A thorough physical characterisation the included transmission electron microscopy, X-ray diffraction asymmetrical flow field-flow fractionation. Their structure was ultimately disclosed an indirect Fourier transform static light...