A5103217581- Antimicrobial Peptides and Activities
- Oral microbiology and periodontitis research
- Spinal Fractures and Fixation Techniques
- Dental materials and restorations
- Genomics and Rare Diseases
- Bacterial Identification and Susceptibility Testing
- Pelvic and Acetabular Injuries
- Diagnosis and Treatment of Venous Diseases
- Invertebrate Immune Response Mechanisms
- Genomic variations and chromosomal abnormalities
- Genetic Neurodegenerative Diseases
- Cardiomyopathy and Myosin Studies
- Corrosion Behavior and Inhibition
- Cardiovascular and Diving-Related Complications
- COVID-19 diagnosis using AI
- Ubiquitin and proteasome pathways
- Tryptophan and brain disorders
- Biotin and Related Studies
- Antibiotic Resistance in Bacteria
- Muscle Physiology and Disorders
- Alzheimer's disease research and treatments
- Neonatal Health and Biochemistry
- Antibiotic Use and Resistance
- Aquaculture disease management and microbiota
- Prenatal Screening and Diagnostics
Qinghai University
2025
Vanderbilt University
2023-2024
Harvard University
2020-2022
Boston Children's Hospital
2020-2022
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
2020-2021
Emory University
2018-2020
Southern Illinois University School of Medicine
2020
University of British Columbia
2016-2020
IntroductionIn late 2019, an outbreak of a new coronavirus named severe acute respiratory syndrome 2 was detected in Wuhan, China. A great percentage patients with this disease developed symptoms dry cough, malaise, and high fever. During time, several requiring assessment treatment endodontic emergencies were directed to the School Hospital Stomatology at Wuhan University, We examined characteristics these patients.MethodsA total 96 mean age 42.24 ± 18.32 years visited general emergency...
Several neurodegenerative diseases including Alzheimer's Disease (AD) are characterized by ubiquitin-positive pathological protein aggregates. Here, an immunoaffinity approach is utilized to enrich ubiquitylated isopeptides after trypsin digestion from five AD and age-matched control postmortem brain tissues. Label-free MS-based proteomic analysis identifies 4291 unique ubiquitylation sites mapping 1682 proteins. Differential enrichment shows that over 800 significantly altered between...
Almost all dental diseases are caused by biofilms that consist of multispecies communities. DJK-5, which is a short D-enantiomeric, protease-resistant peptide with broad-spectrum anti-biofilm activity, was tested for its effect on oral biofilms. Peptide DJK-5 at 10 μg/mL effectively prevented the growth these microbes in culture media time-dependent manner. In addition to prevention growth, completely killed both Streptococcus mutans and Enterococcus faecalis suspended from after 30 minutes...
The genus Caragana, known for its adaptability and high forage value, is commonly planted to rehabilitate barren land prevent desertification. Several Caragana species are also used medicinal purposes. Analysis of synonymous codon usage bias their primary influencing factors in chloroplast genomes aims provide insights into molecular research germplasm innovation plants. GC content the five ranged from 36.00% 37.10%, showing a preference codons ending A/U, although was weak. screening...
Abstract 3‐Hydroxyisobutyryl‐CoA dehydrogenase (HIBCH) deficiency is a rare error in valine catabolism associated with Leigh syndrome‐like phenotype, mitochondrial dysfunction, and increased C4‐OH. We report the most severe case to date full‐term female who presented poor feeding nystagmus on day of life (DOL) 1. Although initial neuroimaging findings were concerning for metabolic disease, further testing was nondiagnostic she discharged DOL 18. She readmitted 22 after apneic episodes...
Titanium alloys have gained popularity in implant dentistry for the restoration of missing teeth and related hard tissues because their biocompatibility enhanced strength. However, titanium corrosion infection caused by microbial biofilms remains a significant clinical challenge leading to failure. This study aimed evaluate effectiveness antibiofilm peptides 1018 DJK-5 on resistance presence
Abstract Pathogenic variants in HPRT1 lead to deficiency hypoxanthine‐guanine phosphoribosyltransferase and are responsible for a spectrum of disorders. The severe phenotype is termed Lesch–Nyhan syndrome (LNS) inherited an X‐linked recessive manner. Most individuals with LNS have profound intellectual physical disabilities throughout life including self‐mutilating behaviors. Here, we present the case male infant who was diagnosed at 3 weeks age via rapid exome sequencing (ES), which...