- HIV/AIDS Impact and Responses
- Air Quality and Health Impacts
- HIV/AIDS Research and Interventions
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Occupational exposure and asthma
- Occupational Health and Safety Research
- Medical Coding and Health Information
- Diagnosis and treatment of tuberculosis
- Global Cancer Incidence and Screening
- COVID-19 Clinical Research Studies
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Hepatitis B Virus Studies
- Immune responses and vaccinations
National Health Laboratory Service
2022-2024
University of the Witwatersrand
2019
Introduction Despite advances in antiretroviral therapy (ART), notable proportion of individuals still present with advanced HIV disease (AHD) at treatment initiation, defined by CD4 counts <200cells/mm3 or WHO stage 3/4 conditions. This group faces higher mortality and more opportunistic infections. While clinical guidelines are available, they do not adequately address the unique needs AHD patients, particularly early treatment. Addressing these gaps could improve care outcomes. Methods...
Outcomes of HIV-infected children have improved dramatically over the past decade, but are undermined by patient loss to follow-up (LTFU). We assessed patterns LTFU among receiving antiretroviral treatment (ART) at a large inner-city HIV clinic in Johannesburg, South Africa between 2005 and 2014. Demographic clinical data were extracted from records under 12 years. Differences characteristics retained care using Wilcoxon rank sum tests or Pearson χ2 tests. Cox proportional hazard models then...
Abstract Background Drug-resistant tuberculosis (DR-TB) epidemic is driven mainly by the effect of ongoing transmission. In high-burden settings such as South Africa (SA), considerable demographic and geographic heterogeneity in DR-TB transmission exists. Thus, a better understanding risk-factors for clustering can help to prioritise resources specifically targeted high-risk groups well areas that contribute disproportionately Methods The study analyzed potential recent SA, using data...
Objective To assess whether decentralising colposcopy services to a primary care facility in inner-city Johannesburg, South Africa raises access colposcopy. Design Before–after study comparing 2 years before and after decentralisation, using clinical records laboratory data on cervical cytology histology. Primary outcome The proportion of all women attending Hillbrow Community Health Centre (HCHC) with an abnormal Papanikolaou (Pap) smear who had post-decentralisation. Setting Charlotte...
Cement workers are exposed to various kinds of occupational hazards, dust being the most hazardous. Despite certain exposure limits on emission air pollutants in place, several people die each year due complications from respiratory disease. This study aimed assess prevalence chronic symptoms among cement dust. A quantitative, descriptive cross-sectional design was employed 81 two production companies Gauteng, South Africa 2018. self-administered questionnaire, anthropometric measurements,...