Ikhwan Rinaldi

ORCID: 0000-0002-6872-8802
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Research Areas
  • Acute Myeloid Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • COVID-19 Clinical Research Studies
  • COVID-19 and healthcare impacts
  • Nutrition and Health in Aging
  • Chronic Lymphocytic Leukemia Research
  • Liver Disease Diagnosis and Treatment
  • Frailty in Older Adults
  • Lymphoma Diagnosis and Treatment
  • Inflammatory Biomarkers in Disease Prognosis
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Sepsis Diagnosis and Treatment
  • Hematological disorders and diagnostics
  • Gut microbiota and health
  • Neutropenia and Cancer Infections
  • Venous Thromboembolism Diagnosis and Management
  • SARS-CoV-2 and COVID-19 Research
  • Diet and metabolism studies
  • Dialysis and Renal Disease Management
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer Genomics and Diagnostics
  • Acute Lymphoblastic Leukemia research
  • Public Health and Nutrition
  • Cancer Immunotherapy and Biomarkers
  • Hemophilia Treatment and Research

University of Indonesia
2015-2024

Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2015-2024

Dharmais Cancer Hospital
2021

We investigated the gut microbiota in patients with non-alcoholic fatty liver disease (NAFLD) and its correlation fibrosis steatosis stratified by body mass index, as reflected controlled attenuation parameter transient elastography values. A cross-sectional study was performed on 37 NAFLD at Cipto Mangunkusumo National General Hospital from December 2018 to March 2019. The fecal samples 16S RNA sequencing using MiSeq next-generation platform (Illumina). more common metabolic syndrome....

10.12938/bmfh.2020-046 article EN Bioscience of Microbiota Food and Health 2020-09-14

Dysbiosis of the gut microbiota has been considered to have a role in nonalcoholic fatty liver disease (NAFLD) progression. However, there is still lack studies regarding this phenomenon.To find difference proportion NAFLD patients based on stages fibrosis.A cross-sectional study was conducted at Dr. Cipto Mangunkusumo Hospital, which largest tertiary referral center. Human fecal samples from who came outpatient clinic were collected consecutively. The stool sample examination performed...

10.1159/000498946 article EN cc-by-nc Case Reports in Gastroenterology 2019-03-07

Abstract Background Readmission is related to high cost, burden, and risk for mortality in geriatric patients. A scoring system can be developed predict the readmission of older inpatients perform earlier interventions prevent readmission. Methods We followed prospectively aged 60 years 30 days, with initial comprehensive assessment (CGA) on admission a tertiary referral centre. Patients were assessed CGA tools consisting FRAIL scale (fatigue, resistance, ambulation, illness, loss weight),...

10.1186/s12877-021-02198-7 article EN cc-by BMC Geriatrics 2021-04-17

Objective This study will test the performance of anal swab PCR when compared with nasopharyngeal as a diagnostic tool for COVID-19. Design An observational descriptive which included hospitalised suspected, or probable cases hopitalised COVID-19 patients, conducted in Dr. Cipto Mangunkusumo National Hospital, Ciputra Mitra Keluarga Depok Hospital and Kelapa Gading Indonesia. Epidemiological, clinical, laboratory radiology data were obtained. Nasopharyngeal swabs specimens collected...

10.1136/bmjgast-2020-000590 article EN cc-by-nc BMJ Open Gastroenterology 2021-05-01

Leukostasis is a medical emergency with high mortality which often occurs in acute myeloid leukemia patients hyperleukocytosis. One of the therapies that can be used for leukostasis leukapheresis. However, whether leukapheresis provide better survival benefit when compared not receiving still unclear. Hence, we aimed to evaluate effect chemotherapy plus combination versus only on 28-day leukostasis.This study was dual-center retrospective cohort using secondary data from records collected...

10.2147/jbm.s312140 article EN cc-by-nc Journal of Blood Medicine 2021-07-01

Background Obesity is a traditional risk factor for type 2 diabetes mellitus (T2DM). However, recent studies reported that metabolically unhealthy obesity (MUO) exerts higher of developing T2DM than healthy (MHO) because its state insulin resistance. This may happen due to metabolic endotoxemia through gut dysbiosis and increased intestinal permeability. Our study aimed know the association permeability using fatty acid-binding protein (I-FABP) with obesity-related patients in Indonesia....

10.1371/journal.pone.0279915 article EN cc-by PLoS ONE 2023-01-26

Since the beginning of COVID-19 pandemic, there has been an overall improvement in patient mortality. However, haematological malignancy patients continue to experience significant impacts from COVID-19, including high rates hospitalization, intensive care unit (ICU) admissions, and In comparison other patients, individuals with chronic myeloid leukemia (CML) generally have better prognosis. This study, conducted using a large database (EPICOVIDEHA), demonstrated that majority CML...

10.1080/10428194.2023.2280886 article EN cc-by Leukemia & lymphoma/Leukemia and lymphoma 2023-11-15

Patients with deep vein thrombosis (DVT) pose high morbidity and mortality risk thus needing fast accurate diagnosis. Wells clinical prediction scores D-dimer testing are traditionally used to rule out patients low probability of DVT. However, has a few limitations regarding its relatively specificity. Neutrophil-lymphocyte ratio (NLR), marker inflammation, was found increase in Hence, we aimed evaluate the role NLR for DVT diagnosis.Data were collected from medical records suspected at...

10.2147/jbm.s291226 article EN cc-by-nc Journal of Blood Medicine 2021-05-01

Background: Non-alcoholic fatty liver disease (NAFLD) is a chronic inflammatory with excessive fat accumulation in the liver. Transient elastography (TE) controlled attenuation parameter (CAP) device and method to examine degree of fibrosis steatosis. However, this not widely available across Indonesia. Neutrophil lymphocyte ratio (NLR) simple marker for inflammation, which has potency predict outcome. This study aims know diagnostic value NLR as indicator steatosis severity. Methods: was...

10.2147/dmso.s330526 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2022-01-01

Malnutrition during hospitalization is linked to increased morbidity and mortality, but there are insufficient studies observing clinical factors contributing weight loss in Indonesia. This study was therefore undertaken determine the rate of factors.

10.4162/nrp.2023.17.2.218 article EN Nutrition Research and Practice 2023-01-01

Introduction: Anemia is a common blood disorder in the elderly which associated with numerous poor medical outcomes. However, there currently no study that assesses anemia prevalence of Indonesian population aged ≥60 years old multiple provinces and analyzes its association handgrip muscle strength using large sample size.

10.7759/cureus.25290 article EN Cureus 2022-05-24

Optimized treatments for relapsed isolated CNS lymphoma (RI-SCNSL) remains under investigation. Temozolomide combination-based therapy, which is often used in glioblastoma may be as potential treatment RI-SCNSL.

10.1002/ccr3.8409 article EN cc-by-nc-nd Clinical Case Reports 2024-03-01

<ns3:p>Background Cytogenetics is a fundamental examination in the course and management of myelodysplastic syndrome (MDS) since it widely used as diagnostic prognostic indicator for disease. Some cytogenetic profiles are associated with higher risk acute myeloid leukemia (AML) transformation. This first study to evaluate profile Indonesian patients MDS. Methods prospective cohort was conducted at Cancer Center several other referral hospitals. Patients primary MDS aged &gt;18 years were...

10.12688/f1000research.143170.1 preprint EN cc-by F1000Research 2024-03-08

Because the majority of colubrid species are considered harmless to human beings, snakebites rarely reported. However, venom Rhabdophis, which is part Colubridae family, procoagulant and leads severe coagulopathy. Here, we present a case disseminated intravascular coagulation with enhanced fibrinolysis following Rhabdophis bite. Although coagulopathy can be treated effectively specific antivenom, this antivenom not widely available in Indonesia. We also found transient hypertension secondary...

10.1590/0037-8682-0314-2015 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2016-08-01

Background: sepsis is a life-threatening organ dysfunction caused by an excessive host immunological response to infection. The incidence of increasing every year, and the primary cause mortality in intensive care units (ICUs). DIC coagulopathy syndrome that causes microvascular macrovascular thrombosis increases risk bleeding due consumptive coagulopathy. pathophysiology complex, further research required investigate involved mechanisms factors. Method: this study prognostic analysis...

10.3390/jcm11216480 article EN Journal of Clinical Medicine 2022-10-31
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