To evaluate the efficacy of coronally advanced flap (CAF) versus tunnel technique (TUN) in covering isolated mid-facial peri-implant soft tissue dehiscences (PSTDs).Twenty-eight participants presenting with non-molar implants exhibiting PSTDs were enrolled and randomized to receive either CAF or TUN, both a connective graft (CTG). The primary outcome study was percentage mean PSTD coverage at 12 months. Secondary endpoints included frequency complete coverage, changes keratinized mucosa...

Abstract Aim To assess the Doppler ultrasonographic tissue perfusion at dental implant sites augmented with connective graft (CTG) using coronally advanced flap (CAF) or tunnel technique (TUN). Materials and Methods Twenty‐eight patients presenting isolated healthy peri‐implant soft‐tissue dehiscence (PSTD) were included in this randomized clinical trial. PSTDs treated either CAF + CTG TUN CTG. Ultrasound scans taken baseline, 1 week, month, 6 months 12 months. Tissue mid‐facial, mesial...

Abstract Aim To investigate whether the lack of keratinized mucosa (KM) affects peri‐implant health after 10 years loading. Materials and Methods Data from 74 patients with 148 implants two randomized controlled studies comparing different implant systems were included analyzed. Clinical parameters including bleeding on probing (BOP), depth (PD), plaque index, marginal bone loss (MBL), KM width (KMW) at buccal sites collected baseline (time final prosthesis insertion), 5‐year postloading....

To evaluate the efficacy of recombinant human platelet-derived growth factor (rhPDGF)-BB combined with a cross-linked collagen matrix (CCM) for treatment multiple adjacent gingival recession type 1 defects (MAGRs) in combination coronally advanced flap (CAF).Thirty patients were enrolled this triple-blind, randomized, placebo-controlled trial and treated either CAF + CCM rhPDGF, or saline. The primary outcome was mean root coverage (mRC) at 6 months. Complete coverage, gain thickness (GT),...

Abstract Background To evaluate the risk indicators associated with midfacial gingival recessions (GR) in natural dentition esthetic regions. Methods Cone‐beam computed tomography (CBCT) results of thirty‐seven subjects presenting 268 eligible teeth were included cross‐sectional study. Clinical measurements presence/absence GR; depth midfacial, mesial, and distal recession; recession type (RT); keratinized tissue width (KT); attached gingiva (AG). Questionnaires utilized to capture...

The field of regeneration interventions in oral and maxillofacial surgeries still represents a challenge for researchers clinicians. Understanding the biological morphological behaviour human cells towards materials used is key to successfully choosing applying appropriate biomaterials specific clinical situations. aim study was evaluation autologous platelet concentrate obtained with different protocols, culture periodontal ligament fibroblasts (HPLF). design included...

Several types of deproteinised bovine bone mineral (DBBM) are available on the market, and each one is obtained with a thermic chemical process that can differ, achieving different results. Currently, several protocols using low temperature suggested to reduce possible particle crystallisation during production process. This study aimed evaluate biomorphological reaction periodontal fibroblast cultures in contact DBBM particles treated low-temperature protocol (Thermagen®) without exposure...

Abstract Aim To apply high‐frequency ultrasound (HFUS) echo intensity for characterizing peri‐implant tissues at healthy and diseased sites to investigate the possible ultrasonographic markers of health versus disease. Materials Methods Sixty patients presenting 60 implants diagnosed as ( N = 30) peri‐implantitis were assessed with HFUS. HFUS scans imported into a software where first‐order greyscale outcomes [i.e., mean (EI)] second‐order assessed. Other interest involved vertical extension...

SARS-CoV-2 propagation in the world has led to rapid growth and an acceleration discoveries publications of various interests. The main focus a consistent number studies been role angiotensin-converting enzyme 2 (ACE2) binding virus its expression inflammatory response after transmission. ACE2 is involved renin–angiotensin system (RAS), whose key regulate counter (ACE), reducing amount angiotensin II increasing 1–7 (Ang1–7), making it promising drug target for treating cardiovascular...

Understanding the biological and morphological reactions of human cells towards different dentinal derivate grafting materials is fundamental for choosing type dentin specific clinical situations. This study aimed to evaluate periodontal ligament fibroblasts (hPLF) exposed derivates particles. The design included in vitro evaluation mineralized dentine (SG), deproteinized demineralized (DDP), (TT) as test bovine bone (BIOS) positive control material. were kept with hPLF cell line,...

It is well known that keratinized mucosa (KM) plays a crucial role for maintaining peri implant health and esthetic outcomes. The Strip Gingival Graft (SGG) technique, which involved an apically positioned flap (APF), in combination with autogenous SGG xenogeneic collagen matrix (XCM), demonstrated its efficacy re-establishing adequate amount of KM width at sites. Nevertheless, it still unclear whether harvesting the from palate (pSGG) or buccal aspect natural dentition (bSGG) affects...

ABSTRACT Aim To assess tissue perfusion changes and wound healing biomarker levels after root coverage procedures with coronally advanced flap in combination the cross‐linked xenogeneic collagen matrix (CCMX), loaded either a placebo or recombinant human platelet‐derived growth factor‐BB (rhPDGF). Methods This study was designed as secondary analysis from previously published clinical trial, it assessed over 6 months around multiple gingival recession defects, treated CCMX alone (control) +...

This study was performed to evaluate the effects of flap design, grafting material, and graft dimension on tension initial volume increase achieved in soft tissue augmentation. Six fresh porcine jaw cadavers were used this study. Each side randomly assigned receive either a standard split-thickness or with palatal island. Following preparation, random allocation employed determine order 4 treatment modalities: 3 mm volume-stable collagen matrix (VCMX), 6 VCMX, subepithelial connective...

As stability is a key determinant of successful regeneration, this paper introduces tack engagement as novel alternative to conventional suturing techniques, aimed at improving the positioning and fixation autogenous tissue grafts. Rigid engagement, widely utilized technique in guided bone regeneration (GBR) protocols for securing membranes, offers stable time-efficient solution that mitigates risks early graft displacement resulting from or delayed volume changes due physiological healing...

To evaluate the long-term dimensional stability of dental ridges two years after soft tissue augmentation using a porcine-derived volume-stable collagen matrix (VCMX) at healing abutment connections. A retrospective study was conducted private clinic from 2021 to 2023, involving 13 patients who underwent delayed single implant placement in both maxillae and mandible. Three months placement, buccal adjacent augmented with VCMX. Intraoral scans were taken three points: (baseline), one-month...

Soft tissue augmentation procedures are often needed at anterior dental implants to address esthetic concerns. The surgical techniques for vertical soft and papilla implant sites, their predictability, outcomes have recently gained popularity among clinicians meet patients' high demands. This study describes the application of tunneled coronally advanced flap reconstruction (verTCAF) treatment peri-implant dehiscences (PSTDs) characterized by loss. Twelve patients with isolated PSTD in...