- Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Systems, Economic Evaluations, Quality of Life
- Respiratory Support and Mechanisms
- Healthcare Policy and Management
- Delphi Technique in Research
- Global Health Care Issues
- Asthma and respiratory diseases
- Chronic Disease Management Strategies
- School Health and Nursing Education
- Health Promotion and Cardiovascular Prevention
- Health disparities and outcomes
- Dutch Social and Cultural Studies
- Emergency and Acute Care Studies
- Financial Reporting and Valuation Research
- Smoking Behavior and Cessation
- Healthcare cost, quality, practices
- Cystic Fibrosis Research Advances
- Respiratory and Cough-Related Research
- Inhalation and Respiratory Drug Delivery
- Auditing, Earnings Management, Governance
- Time Series Analysis and Forecasting
- Multi-Agent Systems and Negotiation
- Health, psychology, and well-being
- Occupational Health and Safety Research
- Quality Function Deployment in Product Design
Erasmus University Rotterdam
2014-2025
Erasmus MC
2005-2023
Institute of Technology Assessment
2005-2016
Institute of Health Economics
2009
University of Calgary
2009
University of Alberta
2009
New York University Press
2009
Cambridge University Press
2009
Section:ChooseTop of pageAbstract <<Executive SummaryContentsOverviewIntroductionMethodsDefinition and ConceptExercise TrainingPulmonary Rehabilitation ...Behavior Change Colla...Body Composition Abnormal...Physical ActivityTiming Pulmonary Rehab...Patient-centered OutcomesProgram OrganizationHealth Care UseMoving ForwardReferencesCITING ARTICLES
<h3>Background:</h3> The effectiveness of pulmonary rehabilitation in advanced COPD is well established, but few data are available less disease. <h3>Methods:</h3> In a 2 year randomised controlled trial, 199 patients with an average moderate airflow obstruction impaired exercise capacity (mean (SD) forced expiratory volume 1 s (FEV<sub>1</sub>) 60 (16)%, peak work load (Wmax) <70%) were to the INTERdisciplinary COMmunity-based management programme (INTERCOM) or usual care. Intervention...
The aim of this study was to determine the total medical costs for treating displaced femoral neck fractures with hemi- or hip arthroplasty in fit elderly patients. mean per patient at 2 years follow-up were €26,399. These results contribute cost awareness. absolute number is rising and increases already significant burden on society. population Dutch sample an international randomized controlled trial consisting fracture patients treated arthroplasty. Patient data health care utilization...
Abstract We aimed to estimate the prevalence, healthcare costs and number of deaths among people with chronic obstructive pulmonary disease (COPD) in England Scotland 2011–2030. adapted Dutch COPD Model by using English Scottish demographic, incidence, smoking prevalence mortality data make projections. In England, was estimated be 1.79% (95% uncertainty interval 1.77–1.81) 2011, increasing 2.19% (1.85–2.33) 2030. Scotland, 2.03% (1.96–2.10) 2011 2.20% (1.98–2.40) These increases were driven...
Despite the increasing popularity of multi-model comparison studies and their ability to inform policy recommendations, clear guidance on how conduct comparisons is not available. Herein, we present guidelines provide a structured approach multiple models interventions against infectious diseases. The primary target audience for these are researchers carrying out model policy-makers using decisions. consensus process used development included systematic review existing effectiveness...
To contribute to evidence-based policy making, a dynamic Dutch population model of chronic obstructive pulmonary disease (COPD) progression was developed. The projects incidence, prevalence, mortality, and costs diagnosed COPD by the Global Initiative for Chronic Obstructive Lung Disease-severity stage 2000–2025, taking into account dynamics changes in smoking prevalence over time. It estimated that all patients 2000, 27% had mild, 55% moderate, 15% severe 3% very COPD. severity distribution...
The study aimed to estimate the cost-effectiveness of interdisciplinary community-based chronic obstructive pulmonary disease (COPD) management in patients with COPD. We conducted a analysis alongside 2-yr randomised controlled trial, which 199 less advanced airflow obstruction and impaired exercise capacity were assigned INTERCOM programme or usual care. consisted training, education, nutritional therapy smoking cessation counselling offered by physiotherapists dieticians hospital-based...
Objective: To examine the cost-effectiveness of varenicline, a new pharmacotherapy to support smoking cessation, compared with currently available pharmacologic alternatives in Netherlands.Methods: The BENESCO-model was used estimate long-term health and economic benefits cessation for cohort smokers making one-time quit attempt. represented population Dutch respect gender, age, prevalence smoking-related diseases included model: COPD, lung cancer, CHD, stroke, asthma exacerbations. model...
Background and objectives: Exacerbations are important outcomes in COPD both from a clinical an economic perspective. Most studies investigating predictors of exacerbations were performed patients participating pharmacological trials who usually have moderate to severe airflow obstruction. This study was aimed investigate whether depend on the population studied. Methods: A network health modelers used data five sources – two population-based (COPDGene ® The Obstructive Lung Disease...
Studies reporting on the cost-effectiveness of cancer screening usually account for quality life losses and healthcare costs owing to but do not future related competing risks. This study aims demonstrate impact medical other diseases in years gained U.S. screening.Cost-effectiveness studies breast, cervical, colorectal were identified using a systematic literature review. Incremental ratios eligible articles updated by adding lifetime expenditures health per quality-adjusted year because...
Estimating the burden of obesity in five European countries (Germany, Greece, Netherlands, Spain and UK) potential health benefits changes care costs associated with a reduction body mass index (BMI).A Markov model was used to estimate long-term obesity. Health states were based on occurrence diabetes, ischaemic heart disease stroke. Multiple registries literature sources derive demographic, epidemiological cost input parameters. For base-case analyses, run for starting cohort healthy obese...
Objectives. To evaluate the impact of adding a respiratory dimension (a bolt-on dimension) to EQ-5D-5L health state valuations. Methods. Based on extensive regression and principal component analyses, 2 candidates were formulated: R1, limitations in physical activities due shortness breath, R2, breathing problems. Valuation interviews for selected bolt-ons performed with representative sample from Dutch general public using standardized interview protocol software EuroQol group. Hybrid...
Background. Evaluation of personalized treatment options requires health economic models that include multiple patient characteristics. Patient-level discrete-event simulation (DES) are deemed appropriate because their ability to simulate a variety characteristics and pathways. However, DES scarce in the literature, details about methods often missing. Methods. We describe 4 challenges associated with modeling heterogeneity structural, stochastic, parameter uncertainty can be encountered...