The immunoglobulin light-chain gene enhancers E kappa 3', lambda 2-4, and 3-1 contain a conserved cell type-specific composite element essential for their activities. This binds B cell-specific heterodimeric protein complex that consists of the Ets family member PU.1 second factor (NF-EM5), whose participation in formation is dependent on presence DNA-bound PU.1. In this report we describe cloning characterization Pip (PU.1 interaction partner), lymphoid-specific most likely NF-EM5. As...

Pip is a lymphoid-restricted IRF transcription factor that recruited to composite elements within immunoglobulin light-chain gene enhancers through specific interaction with the Ets PU.1. We have examined transcriptional regulatory properties of as well requirements for its PU.1 and DNA form ternary complex. demonstrate dichotomous regulator; it specifically stimulates in conjunction PU.1, but represses alpha/beta-interferon-inducible absence Thus, during B-cell activation differentiation,...

Aim . To correlate the prevalence of dental caries to body mass index, daily sugar intake, and oral hygiene status 12-year-old school children Mathura city. Material Methods The study design was cross-sectional included 100 aged 12 years (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn mathvariant="normal">50</mml:mn></mml:math>boys and<mml:math id="M2"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn...

Background: Plagiarism is stealing of some others work or idea without proper citation. It one the biggest challenges faced by scholarly world and far a grim form delinquency in academics. Aim: The study was designed to explore knowledge attitudes dental professionals toward plagiarism. Materials Methods: A questionnaire having 14 questions sent either via e-mails sending printed copies 5000 professionals, while maintaining anonymity all participants. Result: Most know about plagiarism, they...

Aim . To estimate the prevalence of coronal pulp stones in molar teeth dental outpatients Sunam, Sangrur district, Punjab, India, to report any association between occurrence with age, gender, arch, side, and status find out correlation systemic diseases. Materials Methods 500 routine within age group 18–67 years were involved study. Molar bitewing left right side each patient was taken XCP instrument size 2 film. The presence or absence recorded. Chi-square analysis used record compare it...

Science is a dynamic subject and it was never free of misconduct or bad research. Indeed, the scientific method itself intended to overcome mistakes misdeeds. So, we aimed assess various factors associated with retraction articles from 2004 2013. Data were retrieved PubMed Medline using keywords articles, notice, withdrawal article in April 2014 detect retracted Statistical analysis carried out t-test Karl Pearson's correlation coefficient. Results showed that total 2343 between 2013,...

Background: Intricate relationship between epithelium and connective tissue is believed to play a significant role in pathogenesis of odontogenic lesions. Role its well established at the same time mesenchyme cannot be underestimated. Aim: To investigate, compare correlate different types pattern collagen fibers cysts using picrosiriusred stain under polarizing microscopy order delineate exact biological behavior these Materials Methods: The color orientation wall 15 odontogenickeratocysts,...

In head and neck cancer patients undergoing radiotherapy, osteoradionecrosis (ORN) of the jaw is one major but uncommon complications. Satisfactorily results have been observed while treating ORN with upcoming treatment modalities such as combination therapy pentoxifylline Vitamin E (PVe). It believed that in dental extractions, these can be used prophylactically for lowering risk development ORN. Hence, keeping all things mind, we planned present study to assess prophylactic role tocopherol...

This study was to correlate and analyze the imaging features epithelial cell proliferation pattern in different cases of keratocystic odontogenic tumors (KCOT) role inflammation using proliferative markers radiographic patterns KCOT determine its biological behavior. One hundred eighty-six were taken together grouped based on patterns. Forty randomly selected stained a proliferating cellular nuclear antigen marker. The correlation between with without determined. Unilocular variety is most...

Oral diseases are largely preventable and it is hoped that with the early exposure to oral health-care activities, prevalence of will be reduced in children they would more receptive dental services.

Neurilemmoma (Schwannoma) is a benign tumour of neuroectodermal origin. It usually occurs as asymptomatic, solitary, smooth-surfaced and slow growing lesion, emerging at any age, with such, no gender prelidiction. Occurring common in the head neck region, its intraoral presentation very rare. Here, we are reporting rare case schwannoma posterior palate which occurred 34-year-old female patient who had chief complaint painless, swelling on palate.

Clear cell squamous carcinoma (SCC) is an extremely rare heterogenous group of malignant tumour with incompletely understood aetiology. We, hereby present a case clear variant on buccal mucosa in 52-year-old male patient. Histopathology showed sheets cells differentiation and features. Histochemical findings negative staining for Periodic Acid-Schiff (PAS), mucicarmine Oil Red O. Immunohistochemical investigations revealed positive CK 8-18 S-100. We conclude by emphasizing the need careful...

To determine and compare the reliability of pulp tissue in determination sex to analyze whether caries have any effect on fluorescent body test.

Trigeminal neuralgia (TN) is characterized by recurrent attacks of lancinating pain in the trigeminal nerve distribution. Various medicinal and surgical procedures have been utilized for treatment TN. Over time, several drugs other than carbamazepine used but none them shown satisfying results.The objective study to evaluate effectiveness combination with baclofen or capsaicin management TN.A total 45 patients diagnosed TN were randomly divided into three groups. The prescribed Group 1, 2,...

Ameloblastomas are regarded as a homogeneous group of neoplasms with locally invasive character. They generally do not show induction dental hard tissue formation except in few cases. Biological behavior and histogenesis these tumors is still unexplored there lack relevant studies long follow-up patients. So, we aimed to report this rare case dentinoameloblastoma unique presence ghost cells middle-aged female involving maxilla emphasis on its biological behavior. We conclude that although...