A5101404564- Crystallization and Solubility Studies
- Plant Gene Expression Analysis
- X-ray Diffraction in Crystallography
- Plant biochemistry and biosynthesis
- Phytochemicals and Antioxidant Activities
- Metal complexes synthesis and properties
- Plant tissue culture and regeneration
- Glioma Diagnosis and Treatment
- Enzyme Production and Characterization
- Metal-Catalyzed Oxygenation Mechanisms
- Wheat and Barley Genetics and Pathology
- Advanced biosensing and bioanalysis techniques
- Cancer Immunotherapy and Biomarkers
- Metal-Organic Frameworks: Synthesis and Applications
- Biofuel production and bioconversion
- MicroRNA in disease regulation
- Folate and B Vitamins Research
- RNA modifications and cancer
- Natural product bioactivities and synthesis
- Musculoskeletal pain and rehabilitation
- Phytase and its Applications
- CRISPR and Genetic Engineering
- Nonlinear Waves and Solitons
- Transgenic Plants and Applications
- Genomics, phytochemicals, and oxidative stress
First Affiliated Hospital of Zhengzhou University
2019-2025
Inner Mongolia University
2025
Nanjing University of Finance and Economics
2025
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
2024
Liaocheng University
2007-2024
Soochow University
2024
First Affiliated Hospital of Henan University
2022-2023
Anhui Agricultural University
2022-2023
Zhengzhou University
2019-2023
Health Biomed (China)
2023
Rheumatoid arthritis (RA) is a chronic inflammatory disorder linked to oxidative stress of rheumatoid fibroblast-like synoviocytes (RA-FLSs). The effects and potential mechanism salicin on inflammation RA-FLSs were examined by MTT, ELISA, Western blot methods. Salicin significantly reduced cell viability (82.03 ± 7.06, P < 0.01), cytokines (47.70 1.48 ng/L for TNF-α, 30.03 3.49 IL-6) ( matrix metalloproteinases-1/-3 expression 0.01) in IL-1β-induced inhibited ROS generation p65...
Radish [Raphanus sativus (Rs)] is an important dietary vegetable in Asian countries, especially China, Japan, and Korea. To elucidate the molecular mechanisms of anthocyanin accumulation radish, gene expression enzymes directly involved biosynthesis was analyzed. These genes include phenylalanine ammonia lyase (PAL), cinnamate 4-hydroxylase (C4H), 4-coumarate-CoA ligase (4CL), chalcone synthase (CHS), isomerase (CHI), flavanone 3-hydroxylase (F3H), dihydroflavonol reductase (DFR),...
This study investigated the effect of methyl jasmonate (MeJA) on metabolic profiles and rosmarinic acid (RA) biosynthesis in cell cultures Agastache rugosa Kuntze. Transcript levels phenylpropanoid biosynthetic genes, i.e., ArPAL, Ar4CL, ArC4H, maximally increased 4.5-fold, 3.4-fold, 3.5-fold, respectively, compared with untreated controls, culture contained relatively high amounts RA after exposure cells to 50 µM MeJA. were 2.1-, 4.7-, 3.9-fold higher 10, 50, 100 MeJA, than those controls....
Summary Excessive production of reactive oxygen species (ROS) by an overactive nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system in penile tissue is important mechanism erectile dysfunction (ED). S ‐allyl cysteine (SAC), a bioactive component derived from garlic, was recently reported to exert versatile antioxidant properties. We hypothesized that SAC would be able resolve diabetes‐related ED reducing ROS generation, and designed this study investigate possibility as well...
Anthocyanins are distributed ubiquitously to terrestrial plants and chalcone isomerase (CHI) catalyzes the stereospecific isomerization of chalcones - a committed step in anthocyanin biosynthesis pathway. In this study, one gene encoding CHI was isolated from Ophiorrhiza japonica designated as OjCHI. Multiple sequence alignments phylogenetic analysis revealed that OjCHI had conserved active site residues classified into type I group. order better understand mechanisms synthesis O. japonica,...
Late spring coldness (LSC) is critical for wheat growth and development in the Huang-Huai valleys of China. However, little known about molecular mechanisms young spikes responding to low temperature (LT) stress during anther connective tissue formation phase (ACFP). To elucidate associated with temperature, we performed a comparative transcriptome analysis cultivars Xinmai26 (XM26: cold-sensitive) Yannong19 (YN19: cold-tolerant) using RNA-seq data. Over 4000 differently expressed genes...
Late spring cold (LSC) occurred in the reproductive period of wheat impairs spike and floret differentiation during period, when young spikelets are very cold-sensitive. However, under LSC, responses at various positions, leaves, stems interactions between them physiological levels remain unclear. In present study, two-year treatments terminal spikelet stage two temperatures (2 °C, −2 °C) durations (1, 2, 3 days) were imposed an artificial climate chamber to compare effects LSC on grain...
Korean mint (Agastache rugosa), a perennial, medicinal plant of the Labiatae family, has many useful constituents, including monoterpenes and phenylpropanoids. Among these, tilianin rosmarinic acid, 2 well-known natural products, have pharmacologically properties. Chalcone synthase (CHS) chalcone isomerase (CHI) catalyze first second committed steps in phenylpropanoid pathway plants, leading to production tilianin. In this study, cDNAs encoding CHS (ArCHS) CHI (ArCHI) were isolated from A....
Open AccessCCS ChemistryRESEARCH ARTICLE1 May 2022Extracellular Milieu and Membrane Receptor Dual-Driven DNA Nanorobot for Accurate in Vivo Tumor Imaging Kun Yuan, Hong-Min Meng, Yanan Wu, Juan Chen, Hui Xu, Lingbo Qu, Lele Li Zhaohui Yuan College of Chemistry, Green Catalysis Center, Henan Joint International Research Laboratory Construction Functional Molecules Their Bioanalytical Applications, Zhengzhou Key Nanomaterial Medical Theranostic, University, 450001 , Meng *Corresponding...
This research intended to investigate vitamin B6, B9, and B12 consumption in relation the risk of low cognitive performance (LCP) among elderly adults.We analyzed data 2421 participants retrieved from National Health Nutrition Examination Survey (NHANES) 2011-2014 database this cross-sectional study. Cognitive was evaluated by Consortium Establish a Registry for Alzheimer's disease (CERAD) word learning recall modules, animal fluency test (AF), digit symbol substitution (DSST). Participants...
Rosmarinic acid, an important phenolic compound, is commonly found in species of the Boraginaceae and subfamily Nepetoideae Lamiaceae. However, it also other higher plant families some fern hornwort species. acid has a number interesting biological activities, e.g. antiviral, antibacterial, anti-inflammatory, antioxidant. The presence rosmarinic medicinal plants, herbs spices beneficial health promoting effects. In supposed to act as preformed constitutively accumulated defence compound....
The ginsenoside content of berries and roots three cultivars Korean ginseng have been investigated. For all cultivars, Re was the most abundant in berries. However, produced more total ginsenosides, berry profile differed from that roots. 4-6 times than Averaged across amounts five ginsenosides > Rc approximately = Rg1 Rb1 Rd. roots, were Roots Yunpoong cultivar had greatest content, followed by Chunpoong Gumpoong cultivar. amount (especially Rb1, Re, Rg1)
Amomum villosum Lour., produced from Yangchun, Guangdong Province, China, is a Daodi medicinal material of Amomi Fructus in traditional Chinese medicine. This herb germplasm should be accurately identified and collected to ensure its quality safety medication. In the present study, single nucleotide polymorphism typing method was evaluated on basis DNA barcoding markers identify Fructus. Genomic extracted leaves 29 landraces representing three species (A. A. xanthioides Wall. ex Baker...
SWEETs (sugars will eventually be exported transporters) are a novel class of recently identified sugar transporters that play important roles in diverse physiological processes. However, only few species the plant SWEET gene family have been functionally identified. Up till now, there has no systematic analysis Cucurbitaceae crops. Here, genome-wide characterization this was conducted cucumber (Cucumis sativus L.). A total 17 CsSWEET genes were identified, which not evenly distributed over...
Medicago ruthenica is a forage legume crop that widely used as fodder and for ecological restoration in arid semi-arid areas Northcentral Asia. During the seedling stage, weeds challenge growth development of M. ruthenica, especially fields sown seed production. However, strategies to effectively control crops using herbicides have not been investigated. We evaluate efficacy different pre- post-emergence ruthenica. The results indicated most effective pre-emergence herbicides, imazethapyr...
Integrating multimodal data can uncover causal features hidden in single-modality analyses, offering a comprehensive understanding of disease complexity. This study introduces fusion subtyping (MOFS) framework that integrates radiological, pathological, genomic, transcriptomic, and proteomic from 122 patients with IDH-wildtype adult glioma, identifying three subtypes: MOFS1 (proneural) favorable prognosis, elevated neurodevelopmental activity, abundant neurocyte infiltration; MOFS2...