Laura Benaglia

ORCID: 0000-0002-7404-9830
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About
Contact & Profiles
Research Areas
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Gynecological conditions and treatments
  • Ovarian function and disorders
  • Reproductive System and Pregnancy
  • Intestinal and Peritoneal Adhesions
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive Biology and Fertility
  • Sexual Differentiation and Disorders
  • Growth Hormone and Insulin-like Growth Factors
  • Thyroid Disorders and Treatments
  • Ovarian cancer diagnosis and treatment
  • Ectopic Pregnancy Diagnosis and Management
  • Maternal and Perinatal Health Interventions
  • Maternal and fetal healthcare
  • Reproductive Health and Contraception
  • Urological Disorders and Treatments
  • Genetic Syndromes and Imprinting
  • Pregnancy-related medical research
  • Menstrual Health and Disorders
  • Gender Roles and Identity Studies
  • Female Genital Mutilation/Cutting Issues
  • Sperm and Testicular Function
  • Omental and Epiploic Conditions
  • Muscle and Compartmental Disorders

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2016-2025

University of Milan
1999-2020

Ospedale Maggiore
2006-2015

Imperial College London
2013

IVI Madrid Clinic
2011

Newton Wellesley Hospital
2009

Cleveland Clinic
2009

Instituto Tropical de Medicina Reprodutiva
2009

Istituti di Ricovero e Cura a Carattere Scientifico
2008

Weatherford College
2008

There is growing and consistent evidence showing that ovarian reserve affected following surgical excision of endometriomas. Of particular concern the risk severe damage leading to unresponsiveness hyperstimulation. In this study, we aimed determine rate complication.Ninety-three women underwent surgery for monolateral endometriomas were recruited. Patients who IVF selected and, in all cases, follicular growth was monitored by serial transvaginal ultrasonography. The main outcome measure...

10.1093/humrep/dep464 article EN Human Reproduction 2010-01-17

The influence of previous conservative surgery for endometriomas on IVF-ICSI outcome is debated. Conflicting information emerging from the literature may be consequent to fact that are mostly monolateral. contralateral intact ovary adequately supply reduced function affected one. To clarify this point, we assess in women operated bilateral endometriomas.Women selected cycles who previously underwent cystectomy were matched (1:2) age and study period with patients did not undergo prior...

10.1093/humrep/den133 article EN Human Reproduction 2008-04-18

A growing body of evidence suggests that ovarian reserve is damaged after excision endometriomas. However, it may not be excluded gonadal damage at least partly caused by the very presence an endometrioma per se, thus preceding surgery. To clarify this aspect, we set up a prospective study in women with monolateral endometriomas order to assess rate ovulation affected ovaries.Seventy who had undergone previous adnexal surgery underwent serial ecographic examinations determine side...

10.1093/humrep/dep202 article EN Human Reproduction 2009-06-05

Recent in vitro and vivo experimental evidence supports a role of vitamin D insufficiency as an important factor the development uterine leiomyomas. However, epidemiological data supporting this possibility are scanty.Our objective was to investigate status women with without leiomyomas.This case-control study referring 2 infertility units Italy. Women were eligible cases if they diagnosed at least 1 leiomyoma mean diameter ≥10 mm transvaginal ultrasound. Each them matched subsequent same...

10.1210/jc.2013-1777 article EN The Journal of Clinical Endocrinology & Metabolism 2013-07-04

The increasing confidence with the techniques of oocyte and ovarian cortex freezing has prompted their potential use for patient categories other than those at risk early menopause due to cancer treatments. Women affected by every iatrogenic or pathologic condition known compromise function severely have been considered as candidates fertility preservation. Among them, women endometriosis may represent a particularly suitable group since they are increased premature exhaustion about half...

10.1093/humrep/dev078 article EN Human Reproduction 2015-04-16

Are women with endometriosis who conceive IVF at increased risk of preterm birth?Women do not face an birth.The eutopic endometrium has been repeatedly shown to present molecular and cellular alterations. On this basis, it hypothesized that pregnancy outcome may be altered in affected women. However, date, available evidence from epidemiological studies is scanty conflicting. Data tended partly consistent only for birth placenta previa.Retrospective matched case-control study achieving...

10.1093/humrep/dew210 article EN Human Reproduction 2016-09-24

BACKGROUNDThere is a growing consensus that ovarian endometriomas should not be systematically removed in women selected for IVF. However, some recent evidence suggested the presence of these cysts may negatively affect course pregnancy.

10.1093/humrep/des054 article EN Human Reproduction 2012-03-23

A possible and neglected concern in women with endometriosis undergoing IVF is the potential risk of progression disease. We set up a prospective study mainly aimed at evaluating impact on endometriosis-related symptoms.Women surgical or echographic diagnosis selected for were included. In month preceding attempt second evaluation 3-6 months after cycle, who did not get pregnant underwent clinical assessment transvaginal ultrasonography. Each patient was requested to complete questionnaire...

10.1093/humrep/der208 article EN Human Reproduction 2011-06-29

BACKGROUND The impact of fibroids, not encroaching the endometrial cavity, have on rate success IVF is still controversial. Recent meta-analyses suggest a detrimental effect intramural lesions but subserosal lesions. However, they also emphasize need for further evidence. In order to elucidate this, we designed prospective cohort study compare in women with and without fibroids. METHODS Exposed were those asymptomatic or fibroids diameter below 50 mm who selected IVF. Unexposed free matched...

10.1093/humrep/der015 article EN Human Reproduction 2011-02-11

Abstract There is growing interest on the potential clinical relevance of endometrial microbiome. However, insufficient attention has been given to methodology sampling. To minimize contamination, we advocate use double-lumen catheters commonly employed for embryo transfer. Endometrial fluid samples obtained from 53 women scheduled IVF were studied microbiome characterization. Control vagina these same concomitantly obtained. Samples analysed by V3–V4–V6 regions 16S rRNA gene sequencing with...

10.1038/s41598-022-12095-7 article EN cc-by Scientific Reports 2022-05-19

There is a growing consensus that ovarian reserve reduced after surgical excision of endometriomas. However, it remains to be fully clarified whether this damage precedes or follows surgery. In order further elucidate aspect, we evaluated responsiveness hyperstimulation in women selected for IVF with unilateral unoperated The main aim study was compare the number developing follicles affected ovary contralateral intact gonad as control. Patients who were diagnosed one more monolateral...

10.1093/humrep/der097 article EN Human Reproduction 2011-04-07

Several studies aimed to disentangle whether pregnancy influences the growth of uterine fibroids but results were inconsistent. In this study, we speculated that fibroid enlargement during may not be linear and hypothesized phenomenon mainly occur initial pregnancy. To test hypothesis, set up a prospective cohort study women with undergoing IVF. Cases achieving viable Controls subsequent failing become pregnant. Twenty-five cases 25 controls recruited. The total number in two groups was 46...

10.1371/journal.pone.0085933 article EN cc-by PLoS ONE 2014-01-20
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