A5039782204- Phytochemistry Medicinal Plant Applications
- Probiotics and Fermented Foods
- Advanced Drug Delivery Systems
- Healthcare Regulation
- Postharvest Quality and Shelf Life Management
- Nanocomposite Films for Food Packaging
- Listeria monocytogenes in Food Safety
- Protein Hydrolysis and Bioactive Peptides
- Wound Healing and Treatments
- Analytical Methods in Pharmaceuticals
- Drug Solubulity and Delivery Systems
- Smart Agriculture and AI
- Food Safety and Hygiene
- Lichen and fungal ecology
- Proteins in Food Systems
- Food composition and properties
- Diagnosis and Treatment of Venous Diseases
- Infection Control and Ventilation
- Polysaccharides and Plant Cell Walls
- Syphilis Diagnosis and Treatment
- Tissue Engineering and Regenerative Medicine
- Spectroscopy and Chemometric Analyses
- Bacterial biofilms and quorum sensing
- Polysaccharides Composition and Applications
- Intraocular Surgery and Lenses
Universidade Federal de Pernambuco
2009-2024
Universidade Federal de Pelotas
2015
Blücher (Germany)
2014
The effect of microencapsulation L. acidophilus La-05 (8 log CFU/mL) by external ionic gelation technique in alginate (30 g/L; AM) and coated with a low molecular weight chitosan solution (5 AC5M) on the survival freeze-dried probiotic culture during storage (7 °C; 0, 7, 15, 30, 60, 90 120 days), exposure to temperature (72, 85 °C), pH (2, 4, 6), NaCl (10, 15 20 g/L) were studied. Furthermore, vegan milks (soybean rice milks) added microencapsulated cultures evaluated for physicochemical...
The present study aimed to evaluate the in vitro antibacterial and antibiofilm activity of bacterial cellulose hydrogel produced by Zoogloea sp. (HYDROGEL) containing vancomycin (VAN) against strains that cause wound infections, such as multidrug-resistant (MDR) Staphylococcus aureus epidermidis. Initially, HYDROGEL was obtained from sugar cane molasses, scanning electron microscopy (SEM) performed determine morphological characteristics. Then, VAN incorporated into (VAN-HYDROGEL). VAN,...
Abstract Chronic venous ulcers (CVU) of the lower limbs (LL) are common and cause psychological changes significant social impact, as they make patient susceptible to pain, absence from work bonds. Some materials suggested dressings for treatment CVU, but expensive generally not available use in public health services. To evaluate efficacy chronic ulcer using bacterial cellulose (BC), gel multi-perforated film associated. A randomized controlled clinical-intervention study was performed...
Mycobacterium tuberculosis (Mtb) has acquired resistance and consequently the antibiotic therapeutic options available against this microorganism are limited. In scenario, use of usnic acid (UA), a natural compound, encapsulated into liposomes is proposed as new approach in multidrug-resistant (MDR-TB) therapy. Thus aim study was to evaluate effect encapsulation UA liposomes, well its combination with antituberculous agents such rifampicin (RIF) isoniazid (INH) MDR-TB clinical isolates. The...
The present study describes the use of fucoidan, a negative sulfated polysaccharide, as coating material for development liposomes targeted to macrophages infected with Mycobacterium tuberculosis . First, fucoidan was chemically modified obtain hydrophobized-fucoidan derivative (cholesteryl-fucoidan) using two-step microwave-assisted (μW) method. total reaction time decreased from 14 hours 1 hour while maintaining overall yield. Cholesterylfucoidan then used prepare surface-modified...
To determine the release profile of moxifloxacin encapsulated in liposomes aqueous humor as a controlled system for intracameral application.Liposomes containing were obtained using lipid film hydration method and characterized by particle size encapsulation efficiency. Female rabbits used vivo study. Liposomes was injected into anterior chamber right eye each animal. The divided five groups, sample collected 2, 4, 8, 24, 48 h after administration administration. Moxifloxacin concentrations...
Background/objective The aim was to evaluate the use of bacterial cellulose film and bile duct autograft in repairing critical common injury pigs. Methods A prospective experimental analytical study carried out on 20 Sus Domesticus, Piau suidae swine, divided into a control group ( n = 10) an two subgroups: E1 E2 which randomly allocated. underwent complete sections 10 mm apart, while with single defect section longitudinal shaft edge resection. defects were treated end-to-end conventional...
Gums are polysaccharide compounds widely used by food, pharmaceutical and biomedical industries for different purposes, in particular due to their ability stabilize emulsions. In this work, the raw gum of Schinopsis brasiliensis Engl., popularly known as Barauna (GB) was employed oil/water formulations order evaluate its emulsifying activity comparison with commercial Arabic (GA) a positive control. Rheological properties GB GA were also evaluated similar behavior observed. To study each...
The aim of this study was to develop and validate a UV spectrophotometric method for determination LPSF/AC04 from inclusion complex encapsulated into liposomes. validation parameters were determined according the International Conference on Harmonisation (ICH) National Health Surveillance Agency (ANVISA) guidelines. at 250 nm in methanol by method, exhibiting linearity range 0.3 2 µg.mL−1 (Absorbance=0.18068 x [LPSF/AC04 µg.mL-1] + 0.00348), (r2=0.9995). limits detection quantification...
Anadenanthera colubrina var. cebil (Griseb.) Altschul, a plant often found in areas of the Caatinga northeastern Brazil, is widely used unconventional medicine for treatment infections and inflammations. Thus, aim present study was to evaluate antibacterial activity A. bark extracts against methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates, investigate if intact regenerated have same effect MRSA determine interaction between these antibiotics. The performed by...
O ácido retinóico (AR) tem sido utilizado para o tratamento de acne severa, rugas, estrias e celulite, no entanto, provoca irritação na pele sofre rápida degradação quando exposto à luz ao calor. Métodos analíticos rápidos quantificação do AR são, portanto, necessários ensaios cinética liberação in vitro. Nesse contexto, objetivo deste trabalho foi desenvolver validar um método rápido sensível doseamento em microcápsulas alginato/quitosana contendo óleo babaçu dispersas gel natrosol® por...
O tratamento de infecções causadas por enterobactérias produtoras enzimas β-lactamases espectro estendido (ESBLs) está cada vez mais desafiador, forma que o uso indiscriminado e exacerbado antibióticos promoveu a resistência disseminação bacteriana destes patógenos, tornando destas bactérias um desafio para saúde pública. Levando em consideração os aminoglicosídeos são indicados clínico pelas enterobactérias, objetivo dessa revisão foi descrever utilização eficácia dos como estratégia...
O objetivo deste estudo foi avaliar o nível de conhecimento universitários Vitória Santo Antão sobre a sífilis. Trata-se uma pesquisa exploratória transversal com abordagem quantitativa e qualitativa, realizada os estudantes em Antão, Pernambuco, através da aplicação um questionário. Esse questionário possuía 39 questões objetivas 3 subjetivas para dos sífilis, estimando prevalência infecção por sífilis entre relacionando presença as condições socioeconômica demográfica estudantes. Os...
Introdução: O surgimento e disseminação de bactérias multirresistentes consistem em relevantes problemas saúde pública. Neste contexto, infecções ocasionadas por Staphylococcus aureus resistentes à meticilina (MRSA) podem apresentar elevada morbimortalidade. Nesse âmbito, a comunidade científica tem empreendido esforços para desenvolver ou descobrir novas classes antibióticos, assim como propor o sinergismo entre moléculas. Desta forma, objetivo deste estudo consistiu avaliar extratos da...
Este estudo teve como objetivo analisar a segurança e eficácia da celulose bacteriana (CB) produzida partir do melaço de cana-de- açúcar, através estudos conduzidos publicados pelo Grupo Pesquisa sobre Biopolímeros Cana-de-Açúcar, vinculados à POLISA©, para Saúde. Trata-se uma revisão narrativa literatura que foi conduzida acervo publicações biopolímero cana-de-açúcar, Foram selecionados 21 entre os anos 2002 2020, sendo 11 relacionados avaliação pré-clínica 10 clínica. Os envolvendo...