Zhiyuan Wang

ORCID: 0000-0002-7510-087X
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About
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Research Areas
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Orthodontics and Dentofacial Orthopedics
  • Advanced machining processes and optimization
  • Dental Implant Techniques and Outcomes
  • dental development and anomalies
  • Advanced Surface Polishing Techniques
  • Cleft Lip and Palate Research
  • Advanced Machining and Optimization Techniques
  • Dental Radiography and Imaging
  • Hip and Femur Fractures
  • Craniofacial Disorders and Treatments
  • Nerve injury and regeneration
  • Metal complexes synthesis and properties
  • Spinal Cord Injury Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Knee injuries and reconstruction techniques
  • Temporomandibular Joint Disorders
  • Endodontics and Root Canal Treatments
  • Pelvic and Acetabular Injuries
  • Neurological Disease Mechanisms and Treatments
  • Dental materials and restorations
  • Hip disorders and treatments
  • Reconstructive Surgery and Microvascular Techniques
  • Ferrocene Chemistry and Applications

Guangxi University
2021-2025

Fudan University
2025

Harbin University of Science and Technology
2022-2024

First Affiliated Hospital of Kunming Medical University
2019-2024

Kunming Medical University
2019-2024

Infotech Soft (United States)
2024

Xi'an Honghui Hospital
2017-2024

Xi'an Jiaotong University
2017-2024

Hunan Cancer Hospital
2010-2024

Weatherford College
2024

Neural stem cells (NSCs) are considered to be prospective replacements for neuronal cell loss as a result of spinal cord injury (SCI). However, the survival and differentiation NSCs strongly affected by unfavorable microenvironment induced SCI, which critically impairs their therapeutic ability treat SCI. Herein, strategy fabricate PDGF-MP hydrogel (PDGF-MPH) microspheres (PDGF-MPHM) instead bulk hydrogels is proposed dramatically enhance efficiency platelet-derived growth factor mimetic...

10.1021/acsnano.2c12017 article EN ACS Nano 2023-02-14

Pelvic reconstruction after hemipelvectomy can greatly improve the weight-bearing stability of supporting skeleton and patients' quality life. Although an autograft be used to reconstruct pelvic defects, most suitable choice autograft, i.e., use either femur or tibia, has not been determined. We aimed analyze mechanical stresses a ring reconstructed using tibia finite element (FE) analysis.FE models normal pelvis were established based on computed tomography images, stress distributions...

10.1186/1477-7819-12-1 article EN cc-by World Journal of Surgical Oncology 2014-01-01

Abstract Topographical guidance and chemotaxis are crucial factors for peripheral nerve regeneration. This study describes the preparation of highly aligned poly(ε‐caprolactone) (PCL) fiber conduits coated with a concentration gradient growth factor (NGF) (A/G‐PCL) using newly designed electrospinning receiving device. The A/G‐PCL confirmed in vitro to enhance attract neurite longitudinal dorsal root ganglion (DRG) neurons toward their high‐concentration side. In vivo, observed direct...

10.1002/adfm.202002610 article EN cc-by-nc Advanced Functional Materials 2020-08-13

Clear aligner treatment has become popular over recent years. It is necessary to identify methods by which we could avoid the bowing effect in extractions with clear aligner. The present study was appropriate method design torque movement involving upper anterior teeth of extraction cases, order maintain or improve axis and a during closure space.As height power ridge increased, rotation angle central incisor sagittal direction decreased gradually location center changed significantly; moved...

10.1186/s40510-022-00421-8 article EN cc-by Progress in Orthodontics 2022-08-01

Abstract Introduction The effects of upper-molar distalization using clear aligners in combination with Class II elastics for anchorage reinforcement have not been fully investigated yet. objective this study is to analyze the movement and stress whole dentition further explore guidelines selection traction methods. Methods Three-dimensional (3D) finite element models are established simulate sequential molar process, including initial 2 nd (Set I) 1 st II). Each group set features three...

10.1186/s12903-022-02526-2 article EN cc-by BMC Oral Health 2022-12-01

The aim of this study was to investigate the pro-angiogenic potential olfactory ensheathing cells (OECs) activated by curcumin (CCM) and lipopolysaccharide (LPS) possible underlying mechanisms.Vascular endothelial or tissues were cultured treated with conditioned medium (CM) extracted from OECs through addition LPS CCM unactivated controls. Concomitantly, assessed in vitro aortic ring sprouting assay, wound healing CCK-8 tube formation assay. Subsequently, co-cultured evaluate their...

10.1186/s13578-022-00765-y article EN cc-by Cell & Bioscience 2022-03-04

The intricate electrophysiological functions and anatomical structures of spinal cord tissue render the establishment in vitro models for cord-related diseases highly challenging. Currently, both vivo are still underdeveloped, complicating exploration development effective therapeutic drugs or strategies. Organoids cultured from human induced pluripotent stem cells (hiPSCs) hold promise as suitable diseases. However, cultivation organoids predominantly relies on Matrigel, a matrix derived...

10.1021/acsbiomaterials.4c00029 article EN ACS Biomaterials Science & Engineering 2024-04-01

Spinal cord organoids are of significant value in the research spinal cord-related diseases by simulating disease states, thereby facilitating development novel therapies. However, complexity structure and physiological functions, along with lack human-derived inducing components, presents challenges vitro construction human organoids. Here, we introduce a decellularized placenta-derived extracellular matrix hydrogel (DPECMH) and, combined new induction protocol, successfully construct The...

10.1021/acsbiomaterials.4c00067 article EN ACS Biomaterials Science & Engineering 2024-04-09

Summary Shenyang in Northern China has one of the highest reported prevalence rates oral clefts world. To explore risk factors for Shenyang, we carried out a population‐based case‐control study. A total 360 990 births 2000 to 2007 were screened clefts; overall was 1.76 per 1000. The ratio cleft lip with or without palate (CL ± P) : only (CP) 5.60:1. male female 2.02:1. CLP and CL more common males than females sex (SR) 2.88:1 1.86:1 respectively, whereas CP an SR 0.71:1. Using multivariable...

10.1111/j.1365-3016.2009.01025.x article EN Paediatric and Perinatal Epidemiology 2009-03-11

Long noncoding RNA host gene 16 (SNHG16) has a key role in variety of cancer progression. However, the and mechanism SNHG16 osteosarcoma (OS) remain unknown. In this study, we examined functional OS cells through knocked-down by using siRNA. We found that is overexpressed tissues cell lines. Inhibition reduced proliferation, stimulated apoptosis, decreased migration invasion. addition, miR-340 expression cells. The results showed involves invasion sponging miRNA-340. Together, our data...

10.1089/dna.2018.4424 article EN DNA and Cell Biology 2019-02-01

The Chinese IBDV novel variant (nvIBDV), belonging to the genotype A2dB1b, an emerging pathotype that can cause subclinical disease with severe, prolonged immunosuppression, poses a new threat poultry industry. process of global origin, evolution and transmission dynamics nvIBDV, however, is poorly understood. In this study, phylogenetic trees, site substitutions amino acid (aa) highly accurate protein structure modelling, selection pressure, evolutionary nvIBDV were analysed. Interestingly,...

10.1111/tbed.14634 article EN Transboundary and Emerging Diseases 2022-06-19

Abstract Objective To analyse the anterior teeth effects of clear aligners on five different patterns mandibular molar movement and to define most effective configuration be implemented with through finite element analysis. Methods A three-dimensional model a deep overbite in mandible was constructed using cone beam computerized tomography (CBCT) data. The included dentition, periodontal ligaments, attachments, aligners. Five models were created: (1) A: second distalization (0.25 mm); (2) B:...

10.1186/s12903-024-03906-6 article EN cc-by BMC Oral Health 2024-02-10

Eleven copper chloride complexes with substituted 4′-phenyl-terpyridine ligands: high antiproliferative activities against five human carcinoma cell lines, strong affinity for binding DNA as intercalators and multiple molecular docking results.

10.1039/d0dt03989f article EN Dalton Transactions 2021-01-01

Abstract Background Despite the popularity of clear aligner treatment, effect thickness these aligners has not been fully investigated. The objective this study was to assess effects incisor torque compensation with different thicknesses on three-dimensional displacement tendency teeth in cases extraction. Methods Three-dimensional finite element models maxillary dentition extracted first premolars, maxilla, periodontal ligaments, attachments, and were constructed subject Finite Element...

10.1186/s12903-022-02521-7 article EN cc-by BMC Oral Health 2022-11-16

Class II elastics, in combination with clear aligners (CA), are efficient for molar distalization. However, the effects of this on intermaxillary relationship correction have yet to be investigated. This study aimed investigate actual contribution ratio maxillary and mandibular molars total during distalization using elastics CA further explore therapeutic recommendations clinical practice.Finite element models (FEMs) were established, including second (Set I), followed by first II). Model A...

10.1016/j.ajodo.2023.07.007 article EN cc-by-nc-nd American Journal of Orthodontics and Dentofacial Orthopedics 2023-08-20
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