A5036926643- Advanced Neuroimaging Techniques and Applications
- Opioid Use Disorder Treatment
- HIV, Drug Use, Sexual Risk
- EEG and Brain-Computer Interfaces
- Microtubule and mitosis dynamics
- Functional Brain Connectivity Studies
- Neurobiology of Language and Bilingualism
- Hedgehog Signaling Pathway Studies
- Transcranial Magnetic Stimulation Studies
- Cancer-related Molecular Pathways
- Substance Abuse Treatment and Outcomes
- Advanced MRI Techniques and Applications
Drexel University
2023
University of Pennsylvania
2021-2022
Penn Center for AIDS Research
2021
Johns Hopkins Medicine
2021
Johns Hopkins University
2021
Most solid tumors are aneuploid, and p53 has been implicated as the guardian of euploid genome. Previous experiments using human cell lines showed that aneuploidy induction leads to accumulation p21-mediated G1 cycle arrest. We find adherent 2-dimensional (2D) cultures immortalized or cancer activate upon induction, whereas suspension a lymphoid line undergo p53-independent Surprisingly, 3D mouse organotypic from neural, intestinal, mammary epithelial tissues do not arrest in following...
We hypothesized that measures of cortical thickness and volume in language areas would correlate with response to treatment high-definition transcranial direct current stimulation (HD-tDCS) persons primary progressive aphasia (PPA). In a blinded, within-group crossover study, PPA patients (N = 12) underwent 2-week intervention HD-tDCS paired constraint-induced therapy (CILT). Multi-level linear regression (backward-fitted models) were performed assess as predictors tDCS-induced naming...
Background: The opioid epidemic is an increasingly severe problem affecting public health and leading to significant economic burdens on healthcare systems. Overdose reversal training de-stigmatization efforts are common strategies used combat this epidemic. Nevertheless, professionals report a lack of confidence in administering naloxone high stigmatization levels toward people with use disorder (OUD). While one-time educational reduces stigma improves administration confidence, we...
Abstract Background Recent models propose that spread of Alzheimer's disease (AD) pathology may be mediated by white matter connectivity. AD clinical variants exhibit partially distinct patterns gray atrophy. However, it is less clear whether phenotypic differences extend to patients' connectomes. We hypothesized connectivity would differ between healthy controls, amnestic (aAD), and non‐amnestic (naAD), including behavioral variant (bvAD), logopenic‐variant primary progressive aphasia...