Shaun T. O’Keeffe

ORCID: 0000-0002-7682-5004
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About
Contact & Profiles
Research Areas
  • Intensive Care Unit Cognitive Disorders
  • Palliative Care and End-of-Life Issues
  • Restless Legs Syndrome Research
  • Dysphagia Assessment and Management
  • Parkinson's Disease Mechanisms and Treatments
  • Cardiac Arrest and Resuscitation
  • Geriatric Care and Nursing Homes
  • Anesthesia and Sedative Agents
  • Healthcare Decision-Making and Restraints
  • Frailty in Older Adults
  • Emergency and Acute Care Studies
  • Dementia and Cognitive Impairment Research
  • Family and Patient Care in Intensive Care Units
  • Health Systems, Economic Evaluations, Quality of Life
  • Esophageal and GI Pathology
  • Child Nutrition and Feeding Issues
  • Patient-Provider Communication in Healthcare
  • Mental Health and Psychiatry
  • Patient Dignity and Privacy
  • Sleep and Wakefulness Research
  • Anesthesia and Neurotoxicity Research
  • Hip and Femur Fractures
  • Vitamin C and Antioxidants Research
  • Alcoholism and Thiamine Deficiency
  • Vitamin D Research Studies

University Hospital Galway
2016-2025

University of Limerick
1998-2024

Google (United States)
2023

Merlin Park University Hospital
2010-2021

Saolta University Health Care Group
2021

Regeneron (United States)
2020

Ollscoil na Gaillimhe – University of Galway
2014-2020

Health Service Executive
2020

Technological University Dublin
2020

University Hospital Waterford
2020

The relationship between iron status and the restless legs syndrome (RLS) was examined in 18 elderly patients with RLS matched control subjects. A rating scale a maximum score of 10 used to assess severity symptoms. Serum ferritin levels were reduced compared subjects (median 33 μg/1 vs. 59 μg/1, p<0.01, Wilcoxon signed rank test); serum iron, vitamin B12 folate haemoglobin did not differ two groups. inversely correlated symptoms (Spearman's rho -0.53, p < 0.05). Fifteen treated ferrous...

10.1093/ageing/23.3.200 article EN Age and Ageing 1994-01-01

To determine whether delirium is an independent predictor of adverse outcomes hospitalization in older patients.Cohort study.A total 225 people admitted as emergency to acute geriatric unit a university teaching hospital.Subjects were screened for delirium, defined by Diagnostic and Statistical Manual, 3rd Edition criteria, every 48 hours. Outcome measures included mortality, duration hospital stay, hospital-acquired complications, institutional placement. The influence on these was...

10.1111/j.1532-5415.1997.tb04503.x article EN Journal of the American Geriatrics Society 1997-02-01

To examine the reproducibility and responsiveness to change of a six minute walk test quality life measure in elderly patients with heart failure.Longitudinal within patient study.60 failure (mean age 82 years) attending geriatric outpatient clinic, 45 whom underwent repeat assessment three eight weeks later.Subjects standardised completed chronic questionnaire (CHQ), specific questionnaire. Intraclass correlation coefficients (ICC) were calculated using random effects one way analysis...

10.1136/hrt.80.4.377 article EN Heart 1998-10-01

to examine the relative frequency and outcome of clinical subtypes delirium in older hospital patients.prospective observational study.acute geriatric unit a teaching hospital.94 patients with from prospective study 225 admissions.clinical were determined according predefined criteria. Characteristics examined these subgroups included illness severity on admission, prior cognitive impairment, mortality, duration stay hospital-acquired complications.of 94 patients, 20 (21%) had hyperactive...

10.1093/ageing/28.2.115 article EN Age and Ageing 1999-03-01

Since the publication of first European Federation Neurological Societies (EFNS) guidelines in 2005 on management restless legs syndrome (RLS; also known as Willis-Ekbom disease), there have been major therapeutic advances field. Furthermore, RLS is now a part routine neurological practice Europe. New drugs become available, and further randomized controlled trials undertaken. These were undertaken by EFNS collaboration with Society Sleep Research Society.To provide an evidence-based update...

10.1111/j.1468-1331.2012.03853.x article EN European Journal of Neurology 2012-09-03

Gait disturbance is common in patients with Alzheimer's disease (AD). The aim of this study was to analyse the clinical gait syndromes AD using Nutt's classification. Fifty-five who satisfied NINCDS-ADRDA criteria for probable and 55 controls were recruited from a geriatric psychogeriatric unit. Patients classical musculoskeletal or neurological causing excluded. A standardized examination carried out all subjects. Twenty-two (40%) ten (18%) had higher level disorder (p < 0.01). pattern...

10.1093/ageing/25.4.313 article EN Age and Ageing 1996-01-01

Delirium is a common and serious complication of acute illness in elderly patients. The aim this study was to develop validate model for predicting development delirium medical inpatients who did not have on admission. Consecutive admissions an geriatric unit underwent standardized cognitive assessment every 48 hours. diagnosed according DSM-3 criteria. Independent predictors derivation group 100 patients were determined using stepwise logistic regression analysis; the predictive comprised...

10.1093/ageing/25.4.317 article EN Age and Ageing 1996-01-01

Summary The prevalence and significance of restless legs syndrome was assessed in 307 patients presenting to an acute-care geriatric medical service. Fifteen (5%) had syndrome; 13 (87%) these insomnia 10 (67%) reported troublesome or frequent leg symptoms. Of 147 with current insomnia, iron deficiency (serum ferritin &amp;lt; 18 ng/ml) present 4/13 (31%) 8/134 (6%) without (P 0.025). Improvement symptoms noted repletion. These findings suggest that is relatively common the elderly causes...

10.1136/pgmj.69.815.701 article EN Postgraduate Medical Journal 1993-09-01

Abstract Background Use of modified texture diets—thickening liquids and modifying the foods—in hope preventing aspiration, pneumonia choking, has become central to current management dysphagia. The effectiveness this intervention been questioned. We examine requirements for a valid informed consent process approach whether need treatment is always understood or applied by practitioners. Main text Valid requires provision accurate balanced information, that agreement given freely someone who...

10.1186/s12910-023-00885-1 article EN cc-by BMC Medical Ethics 2023-02-07

Restless legs syndrome is characterized by unpleasant, deep-seated paresthesias in the and sometimes arms. These sensations occur at rest are relieved movement. Sleep disturbance common. Many patients also have periodic movements of sleep. Mild symptoms restless up to 5% population. idiopathic most patients, but it may be presenting feature iron deficiency common uremia, pregnancy, diabetes mellitus, rheumatoid arthritis, polyneuropathy. Treatment underlying cause, when possible, usually...

10.1001/archinte.1996.00440030025004 article EN Archives of Internal Medicine 1996-02-12

To determine the responsiveness of serial Mini-Mental State Examinations (MMSEs) for diagnosis and monitoring delirium in elderly hospital patients.Prospective study.University teaching hospital.One hundred sixty-five people admitted to an acute geriatric service.Subjects were assessed using MMSE Confusion Assessment Method on Days 1 6. Changes scores compared between patients who remained free (n=124) those by Day 6 had developed (n=14) or resolution present admission (n=22).A number...

10.1111/j.1532-5415.2005.53266.x article EN Journal of the American Geriatrics Society 2005-05-01

Objective: To investigate the prevalence of headaches and recurrent chest pain in patients with primary Raynaud disease. Design: Postal survey. Setting: disease clinic at Lahey Clinic Medical Center, a tertiary care hospital. Participants: A consecutive series 120 who had been observed for least 2 years, 97 whom received 93 completed questionnaire, control group age- sex-matched hospital employees without phenomenon. Results: Migraine was diagnosed 57 (61%) 21 (23%) (odds ratio, 5.4; 95% Cl,...

10.7326/0003-4819-116-12-985 article EN Annals of Internal Medicine 1992-06-15

A retrospective review of 274 patients who received in-hospital cardiopulmonary resuscitation was performed to determine whether age is independently associated with survival discharge. Eighty-two (29.9 per cent) the were resuscitated initially, but only 25 (9.1 discharged alive. Survival discharge significantly poorer in aged greater than or equal 70 years (6/175; 3.4 less old (19/99; 19.2 (p 0.001). Severity illness, assessed by number diagnoses and a multifactorial morbidity index, did...

10.1093/qjmed/81.3.1005 article EN QJM 1991-12-01

Testing of orientation to time is an important part mental status examination. The validity errors in different aspects temporal was examined older hospital patients as a guide the presence dementia or delirium and measure severity dementia, defined by Global Deterioration Scale.Inpatients outpatients attending acute underwent independent assessments two doctors on same day determine cognitive status. Optimum cut-offs for error scores were calculated maximise sum sensitivity specificity...

10.1136/jnnp.2010.214817 article EN Journal of Neurology Neurosurgery & Psychiatry 2010-09-18

Sixty patients (mean age 80 years) with cognitive impairment who required parenteral fluids for at least 48 h were randomized to receive either intravenous (i.v.) or subcutaneous (s.c.) fluids. There was no significant difference in the mean volume of fluid prescribed over two groups (s.c. 3.3 litres vs. i.v. 3.6 litres) proportion actually administered 0.82 0.76). After adjusting baseline differences, there between serum urea creatinine levels h. Agitation related infusion reported 11 (37%)...

10.1159/000213768 article EN Gerontology 1996-01-01

OBJECTIVE To determine the prevalence of restraint and bedrail use in a British hospital. DESIGN Cross‐sectional observational study. SUBJECTS Six hundred sixty‐eight patients acute medical, surgical, geriatric beds large teaching hospital on single night MEASUREMENTS Observed restraints bedrails. Reasons for were determined by interviews with nursing staff examination case notes. RESULTS Fifty‐six (8.4%) had bedrails raised. No other use. Reported indications were: prevention falls (52...

10.1111/j.1532-5415.1996.tb02944.x article EN Journal of the American Geriatrics Society 1996-09-01

Necropsy studies suggest that thiamine deficiency is under-diagnosed in life, part because the classical clinical presentations are uncommon. Anecdotal reports may contribute to development of delirium, heart failure and peripheral neuropathy elderly patients, but little systematic research has been reported. We examined levels 36 consecutive non-demented, community-dwelling patients admitted an acute geriatric unit. Marginal [thiamine pyrophosphate effect (TPPE) 15-24%] was present 11 (31%)...

10.1159/000213570 article EN Gerontology 1994-01-01
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