- Intensive Care Unit Cognitive Disorders
- Palliative Care and End-of-Life Issues
- Restless Legs Syndrome Research
- Dysphagia Assessment and Management
- Parkinson's Disease Mechanisms and Treatments
- Cardiac Arrest and Resuscitation
- Geriatric Care and Nursing Homes
- Anesthesia and Sedative Agents
- Healthcare Decision-Making and Restraints
- Frailty in Older Adults
- Emergency and Acute Care Studies
- Dementia and Cognitive Impairment Research
- Family and Patient Care in Intensive Care Units
- Health Systems, Economic Evaluations, Quality of Life
- Esophageal and GI Pathology
- Child Nutrition and Feeding Issues
- Patient-Provider Communication in Healthcare
- Mental Health and Psychiatry
- Patient Dignity and Privacy
- Sleep and Wakefulness Research
- Anesthesia and Neurotoxicity Research
- Hip and Femur Fractures
- Vitamin C and Antioxidants Research
- Alcoholism and Thiamine Deficiency
- Vitamin D Research Studies
University Hospital Galway
2016-2025
University of Limerick
1998-2024
Google (United States)
2023
Merlin Park University Hospital
2010-2021
Saolta University Health Care Group
2021
Regeneron (United States)
2020
Ollscoil na Gaillimhe – University of Galway
2014-2020
Health Service Executive
2020
Technological University Dublin
2020
University Hospital Waterford
2020
The relationship between iron status and the restless legs syndrome (RLS) was examined in 18 elderly patients with RLS matched control subjects. A rating scale a maximum score of 10 used to assess severity symptoms. Serum ferritin levels were reduced compared subjects (median 33 μg/1 vs. 59 μg/1, p<0.01, Wilcoxon signed rank test); serum iron, vitamin B12 folate haemoglobin did not differ two groups. inversely correlated symptoms (Spearman's rho -0.53, p < 0.05). Fifteen treated ferrous...
To determine whether delirium is an independent predictor of adverse outcomes hospitalization in older patients.Cohort study.A total 225 people admitted as emergency to acute geriatric unit a university teaching hospital.Subjects were screened for delirium, defined by Diagnostic and Statistical Manual, 3rd Edition criteria, every 48 hours. Outcome measures included mortality, duration hospital stay, hospital-acquired complications, institutional placement. The influence on these was...
To examine the reproducibility and responsiveness to change of a six minute walk test quality life measure in elderly patients with heart failure.Longitudinal within patient study.60 failure (mean age 82 years) attending geriatric outpatient clinic, 45 whom underwent repeat assessment three eight weeks later.Subjects standardised completed chronic questionnaire (CHQ), specific questionnaire. Intraclass correlation coefficients (ICC) were calculated using random effects one way analysis...
to examine the relative frequency and outcome of clinical subtypes delirium in older hospital patients.prospective observational study.acute geriatric unit a teaching hospital.94 patients with from prospective study 225 admissions.clinical were determined according predefined criteria. Characteristics examined these subgroups included illness severity on admission, prior cognitive impairment, mortality, duration stay hospital-acquired complications.of 94 patients, 20 (21%) had hyperactive...
Since the publication of first European Federation Neurological Societies (EFNS) guidelines in 2005 on management restless legs syndrome (RLS; also known as Willis-Ekbom disease), there have been major therapeutic advances field. Furthermore, RLS is now a part routine neurological practice Europe. New drugs become available, and further randomized controlled trials undertaken. These were undertaken by EFNS collaboration with Society Sleep Research Society.To provide an evidence-based update...
Gait disturbance is common in patients with Alzheimer's disease (AD). The aim of this study was to analyse the clinical gait syndromes AD using Nutt's classification. Fifty-five who satisfied NINCDS-ADRDA criteria for probable and 55 controls were recruited from a geriatric psychogeriatric unit. Patients classical musculoskeletal or neurological causing excluded. A standardized examination carried out all subjects. Twenty-two (40%) ten (18%) had higher level disorder (p < 0.01). pattern...
Delirium is a common and serious complication of acute illness in elderly patients. The aim this study was to develop validate model for predicting development delirium medical inpatients who did not have on admission. Consecutive admissions an geriatric unit underwent standardized cognitive assessment every 48 hours. diagnosed according DSM-3 criteria. Independent predictors derivation group 100 patients were determined using stepwise logistic regression analysis; the predictive comprised...
Summary The prevalence and significance of restless legs syndrome was assessed in 307 patients presenting to an acute-care geriatric medical service. Fifteen (5%) had syndrome; 13 (87%) these insomnia 10 (67%) reported troublesome or frequent leg symptoms. Of 147 with current insomnia, iron deficiency (serum ferritin &lt; 18 ng/ml) present 4/13 (31%) 8/134 (6%) without (P 0.025). Improvement symptoms noted repletion. These findings suggest that is relatively common the elderly causes...
Abstract Background Use of modified texture diets—thickening liquids and modifying the foods—in hope preventing aspiration, pneumonia choking, has become central to current management dysphagia. The effectiveness this intervention been questioned. We examine requirements for a valid informed consent process approach whether need treatment is always understood or applied by practitioners. Main text Valid requires provision accurate balanced information, that agreement given freely someone who...
Restless legs syndrome is characterized by unpleasant, deep-seated paresthesias in the and sometimes arms. These sensations occur at rest are relieved movement. Sleep disturbance common. Many patients also have periodic movements of sleep. Mild symptoms restless up to 5% population. idiopathic most patients, but it may be presenting feature iron deficiency common uremia, pregnancy, diabetes mellitus, rheumatoid arthritis, polyneuropathy. Treatment underlying cause, when possible, usually...
To determine the responsiveness of serial Mini-Mental State Examinations (MMSEs) for diagnosis and monitoring delirium in elderly hospital patients.Prospective study.University teaching hospital.One hundred sixty-five people admitted to an acute geriatric service.Subjects were assessed using MMSE Confusion Assessment Method on Days 1 6. Changes scores compared between patients who remained free (n=124) those by Day 6 had developed (n=14) or resolution present admission (n=22).A number...
Objective: To investigate the prevalence of headaches and recurrent chest pain in patients with primary Raynaud disease. Design: Postal survey. Setting: disease clinic at Lahey Clinic Medical Center, a tertiary care hospital. Participants: A consecutive series 120 who had been observed for least 2 years, 97 whom received 93 completed questionnaire, control group age- sex-matched hospital employees without phenomenon. Results: Migraine was diagnosed 57 (61%) 21 (23%) (odds ratio, 5.4; 95% Cl,...
A retrospective review of 274 patients who received in-hospital cardiopulmonary resuscitation was performed to determine whether age is independently associated with survival discharge. Eighty-two (29.9 per cent) the were resuscitated initially, but only 25 (9.1 discharged alive. Survival discharge significantly poorer in aged greater than or equal 70 years (6/175; 3.4 less old (19/99; 19.2 (p 0.001). Severity illness, assessed by number diagnoses and a multifactorial morbidity index, did...
Testing of orientation to time is an important part mental status examination. The validity errors in different aspects temporal was examined older hospital patients as a guide the presence dementia or delirium and measure severity dementia, defined by Global Deterioration Scale.Inpatients outpatients attending acute underwent independent assessments two doctors on same day determine cognitive status. Optimum cut-offs for error scores were calculated maximise sum sensitivity specificity...
Sixty patients (mean age 80 years) with cognitive impairment who required parenteral fluids for at least 48 h were randomized to receive either intravenous (i.v.) or subcutaneous (s.c.) fluids. There was no significant difference in the mean volume of fluid prescribed over two groups (s.c. 3.3 litres vs. i.v. 3.6 litres) proportion actually administered 0.82 0.76). After adjusting baseline differences, there between serum urea creatinine levels h. Agitation related infusion reported 11 (37%)...
OBJECTIVE To determine the prevalence of restraint and bedrail use in a British hospital. DESIGN Cross‐sectional observational study. SUBJECTS Six hundred sixty‐eight patients acute medical, surgical, geriatric beds large teaching hospital on single night MEASUREMENTS Observed restraints bedrails. Reasons for were determined by interviews with nursing staff examination case notes. RESULTS Fifty‐six (8.4%) had bedrails raised. No other use. Reported indications were: prevention falls (52...
Necropsy studies suggest that thiamine deficiency is under-diagnosed in life, part because the classical clinical presentations are uncommon. Anecdotal reports may contribute to development of delirium, heart failure and peripheral neuropathy elderly patients, but little systematic research has been reported. We examined levels 36 consecutive non-demented, community-dwelling patients admitted an acute geriatric unit. Marginal [thiamine pyrophosphate effect (TPPE) 15-24%] was present 11 (31%)...