A5068038114- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Renal Transplantation Outcomes and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical studies and practices
- Pneumocystis jirovecii pneumonia detection and treatment
- Drug-Induced Adverse Reactions
- Antimicrobial Resistance in Staphylococcus
- Chronic Lymphocytic Leukemia Research
- Pneumonia and Respiratory Infections
- Asthma and respiratory diseases
- Renal Diseases and Glomerulopathies
- Antifungal resistance and susceptibility
- Chemotherapy-induced organ toxicity mitigation
- Innovations in Medical Education
- Allergic Rhinitis and Sensitization
- Cancer Treatment and Pharmacology
- Vascular Anomalies and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Analytical Methods in Pharmaceuticals
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Anesthesia and Pain Management
- Problem and Project Based Learning
- Systemic Sclerosis and Related Diseases
- Anesthesia and Sedative Agents
Hopital Universitaire Hedi Chaker
2020-2025
University of Sfax
2022-2025
Tunis El Manar University
2015-2024
Tunis University
2014-2024
Faculté de médecine de Tunis
2012-2024
Hopital Universitaire Habib Bourguiba
2023
University of Hassan II Casablanca
2022
Centre Hospitalier Universitaire de Clermont-Ferrand
2022
Université Ibn Zohr
2022
University of Monastir
2018
The catechol-O-methyltranferase (COMT) is one of the main enzymes that metabolise dopamine in brain. Val158Met polymorphism <i>COMT</i> gene (<i>rs4680</i>) causes a trimodal distribution high (Val/Val), intermediate (Val/Met) and low (Met/Met) enzyme activity. We tested whether modifier age at onset (AAO) Parkinson9s disease (PD). <i>rs4680</i> was genotyped total 16 609 subjects from five independent cohorts European North American origin (5886 patients with PD 10 723 healthy controls)....
Abstract Background Dihydrolipoamide dehydrogenase deficiency (DLDD) (OMIM# 246,900) is an extremely rare inherited metabolic disorder causing neurological and/or liver impairment. The clinical manifestations are mostly characterized by severe impairment in early childhood, hepatic presentations and rarely myopathic manifestations. Case Here, we describe two patients presenting with recurrent episodes of vomiting dysfunction. DLDD was confirmed via sanger sequencing identification the...
Abstract Objectives Thiopurine S-methyltransferase (TPMT) polymorphisms are associated with low or absent enzyme activity and, consequently, increased myelosuppression risk after conventional doses of azathioprine. The distribution frequencies for deficient TPMT genotypes differs between ethnic groups. Due to limited data in Tunisia, we aimed detect variant alleles ( *2, *3B, *3C, *4) Tunisian patients on azathioprine, and investigate the concordance phenotyping genotyping common alleles....
Background This trial aimed to assess the efficacy of Atorvastatin reloading on prevention Contrast-induced nephropathy (CIN) in patients pre-treated with this statin and undergoing coronary catheterization. Methods was a prospective randomized controlled study including chronic atorvastatin therapy. We randomly assigned population Reloading group (AR group), by 80 mg one day before three days after procedure, Non-Reloading (NR who received their usual dose without dose. The primary...
The Common Myrtle (Myrtus communis L.) is rich in antioxidants, particularly anthocyanin. It was recognized for its anti-inflammatory, anti-cancer and anti-thrombotic effects. aim of our work to evaluate the effect on a model hepatic ischemia-reperfusion Rat. Two morphs were chosen: white fruit black Myrtle. Within each morph, leaf separated determine extract organ. Our conducted three steps: (1) Induction ischemia (90 minutes) Wistar Rat; (2) injection 15 minutes before reperfusion; (3)...