A5058277244- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Renal and Vascular Pathologies
- Vasculitis and related conditions
- Platelet Disorders and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Systemic Lupus Erythematosus Research
- Urticaria and Related Conditions
- Organ Donation and Transplantation
- Hepatitis C virus research
- Dialysis and Renal Disease Management
- Systemic Sclerosis and Related Diseases
- Pregnancy and preeclampsia studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Diet and metabolism studies
- Erythropoietin and Anemia Treatment
- Reproductive System and Pregnancy
- T-cell and B-cell Immunology
- Pharmacological Effects and Toxicity Studies
- Renal cell carcinoma treatment
- Eosinophilic Disorders and Syndromes
- Pharmaceutical Economics and Policy
- Lymphoma Diagnosis and Treatment
- Cell Adhesion Molecules Research
- Clinical practice guidelines implementation
University of Bari Aldo Moro
2013-2023
Charles University
2021
RELX Group (Netherlands)
2021
RELX Group (United States)
2021
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
1998-2018
Ospedale San Giovanni Bosco
2007
IRCCS Istituto Auxologico Italiano
2006
University of Milan
2006
Azienda Ospedaliero-Universitaria Careggi
2006
Ospedale Maggiore
2006
Background. Immunoglobulin A nephropathy (IgAN) is the most common cause of chronic renal failure among primary glomerulonephritis patients. The best treatment for IgAN remains poorly defined. We planned a long-term, prospective, open-label, multicentre, centrally randomized controlled trial to assess whether combination prednisone and ramipril was more effective than alone in patients with proteinuric IgAN.
<h3>Abstract</h3> Cost reduction of high-throughput technologies has enabled the monitoring same biological sample across multiple omics studies and timepoints. The goal is to combine longitudinal multi-omics data detect temporal relationships between molecules interactions layers. This can finally lead uncover new regulation mechanisms that could be responsible for causing complex phenotype or disease. However integration diverse still challenging due heterogeneous designs. Moreover,...
Membranoproliferative glomerulonephritis (MPGN) may be a component of generalized vasculitis as well the clinical expression type-II mixed cryoglobulinemia (MC). Several studies have established striking association between hepatitis C virus (HCV) infection and MC. The potential role HCV in pathogenesis MPGN, which occurs almost half cases MC patients, has not been fully investigated, demonstration proteins antigenic constituent glomerular immune deposits remained elusive. Kidney biopsy...
Renal sinus fat (RSF) has been recognized as a risk factor for arterial hypertension. This study was addressed to examine whether also para- and perirenal accumulation is associated higher 24-h mean systolic (SBP) and/or diastolic blood pressure (DBP) levels in overweight obese subjects.A cohort of 42 patients, 29 women 13 men, aged 25-55 years, not treated with any kind drug, examined. Body mass index (BMI), waist circumference (WC), fasting insulin glucose serum levels, resistance...
Background Oat and barley beta-glucans are prebiotic fibers known for their cholesterol-lowering activity, but action on the human gut microbiota metabolism is still under research. Although induction of short-chain fatty acids (SCFA) following ingestion has previously been reported, no study investigated effects proteolytic uremic toxins p-cresyl sulfate (pCS) indoxyl (IS) levels, while others have failed to demonstrate an effect endothelial function measured through flow-mediated dilation...
Abstract Systemic reactive (AA) amyloidosis, leading to renal failure, is a severe complication of most hereditary periodic fever syndromes. The risk developing this life‐threatening condition varies widely among these disorders, being higher for patients affected by familial Mediterranean and tumor necrosis factor receptor–associated syndrome. In spite an acute‐phase response during attacks, amyloidosis has never, date, been described in with the hyperimmunoglobulinemia D syndrome (HIDS)....
ABSTRACT. Primary IgA nephropathy (IgAN) is characterized by recurrent episodes of macroscopic hematuria accompanied upper respiratory tract infections or persistent asymptomatic microscopic with without proteinuria. IgAN may involve one more members a family. Three generations cohort 110 patients biopsy-proven IgAN, living in Southern Italy, were checked for urinalysis, and the relative risk (RR) developing disease was evaluated. A total 19 unrelated familial, 37 suspected, 54 sporadic...