A5045742216- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Diet and metabolism studies
- Medicinal Plant Extracts Effects
- Adipose Tissue and Metabolism
- Essential Oils and Antimicrobial Activity
- Medicinal Plants and Neuroprotection
- Computational Drug Discovery Methods
- Nutritional Studies and Diet
- Consumer Attitudes and Food Labeling
- Gut microbiota and health
- Agricultural and Food Sciences
- Seed and Plant Biochemistry
- Antioxidant Activity and Oxidative Stress
- Nutrition, Genetics, and Disease
- Medicinal Plant Research
- Agriculture Sustainability and Environmental Impact
- Zebrafish Biomedical Research Applications
- Alzheimer's disease research and treatments
- Diet, Metabolism, and Disease
- Dietary Effects on Health
- Food, Nutrition, and Cultural Practices
- Bee Products Chemical Analysis
- Food composition and properties
- Fish biology, ecology, and behavior
Universidade Federal do Rio Grande do Norte
2019-2025
Sidney Kimmel Comprehensive Cancer Center
2023
Johns Hopkins University
2023
Universidade Estadual de Campinas (UNICAMP)
2013-2023
Universidade Federal do Rio Grande
2023
New York University Press
2021
Cambridge University Press
2021
Universidade Federal de Alfenas
2008
Universidade Federal Rural de Pernambuco
2008
Passion fruit (Passiflora edulis), including its leaves, is a rich source of bioactive compounds, as polyphenols. This study investigated the in vitro and vivo antioxidant potential aqueous extract P. edulis leaves identification phenolic compounds by HPLC-PDA ESI-MS/MS analysis. Male Wistar rats were divided two groups (n = 6 per group). Control group received water experimental leaf (Tea) (1.1 mg dry mL− 1), both ad libitum. Total phenols (DPPH, FRAP, ABTS ORAC assay) determined extract....
The bioactive compounds of freeze-dried jaboticaba peel (FJP), serum lipids and the antioxidant status rats fed high-fat diets containing different doses FJP were evaluated. Obesity was induced three groups obese animals received diet with 1%, 2% 4% added (J1, J2 J4, respectively). HPLC–DAD analyses polyphenols in showed four compounds: gallic acid, cyanidin 3-glucoside, ellagic quercetin. saturated fatty acids reduced J1 J4-fed animals. defenses plasma increased All prevented lipid...
Copaifera langsdorffii (copaiba) is a Brazilian exotic fruit, poorly studied regarding its bioactive composition. The aim of this study was to determine compounds, antioxidant and antimutagenic activities copaiba pulp. samples were extracted with different solvents in order analyze polyphenol compounds (Folin Ciocalteau HPLC–DAD), total flavonoids (reaction AlCl3) capacity (FRAP, ORAC, DPPH). fruit showed high content capacity. Phenolic such as gallic acid, epicatechin gallate, catechin,...
Abstract The hyperphosphorylation of microtubule‐associated protein tau (tau) in the hippocampus can be caused by central and peripheral insulin resistance these alterations are related to development tauopathies, such as Alzheimer's disease. In this study, we used a high‐fat diet induce obesity adult Swiss mice checked whether supplementation with Myrciaria jaboticaba berry peel for 10 weeks could improve sensitivity, learning/memory performance, prevent phosphorylation hippocampus....
Passion fruit (Passiflora edulis) peel, a waste from food industrial processing, is still little explored. It contains fibers, including soluble which may be substrate for enteric bacteria and contribute to maintaining bowel health. The purpose of this work was investigate the action P. edulis peel in microbiota, production short-chain fatty acids (SCFAs), antioxidant potential colon Wistar rats. Seventy-seven-day-old male rats were divided into two groups: Peel Control (n = 4). Both groups...
O objetivo do estudo foi avaliar a composição centesimal da farinha obtida casca maracujá e sua atividade antioxidante in vitro, buscando viabilizar suas potencialidades para incorporação em produtos alimentares. Os frutos foram higienizados, as cascas separadas polpa, secas estufa com circulação de ar moídas obtenção uma farinha. Foi determinada os polifenóis presentes na extraídos por três metodologias, tendo sido quantificados o teor fenóis totais métodos distintos (sequestro radical...
The antioxidant and anti-inflammatory effects of the aqueous extract Passiflora edulis leaves, which is a source vitexin, isovitexin isoorientin, was investigated in 2,4,6-trinitrobenzenesulphonic acid induced colitis model. oral intake P. (1100 µg mL−1) improved significantly (P < 0.05) endogenous status decreased lipid peroxidation serum, liver, colon. consumption level pro-inflammatory colon tissue, especially by reducing IL-1β five-fold TNF-α two-fold compared to control group. leaves...
Inflammatory bowel disease is a chronic relapsing that affects millions of people worldwide; its pathogenesis influenced by genetic, environmental, microbiological, and immunological factors. The aim this study was to evaluate the effects short- long-term Passiflora edulis peel intake on antioxidant status, microbiota, short-chain fatty acids formation in rats with 2,4,6-trinitrobenzenesulphonic acid-induced colitis using two "in vivo" experiments: (prevention) acute (treatment). damage...
Abstract BACKGROUND Grape juice consumption may prevent several chronic diseases owing to the presence of phenolic compounds, which have an important role in reduction oxidative stress. This study investigated polyphenol content and antioxidant activities grape juices from two cultivars: BRS ‐Cora Isabella. Total ( TPC ), anthocyanins, capacity (oxygen radical absorbance capacity, ferric reducing power 1,1‐diphenyl‐2‐picrylhydrazyl), profile (high‐performance liquid chromatography with diode...
Natural compounds could be a complementary alternative to inflammatory bowel disease (IBD) management. This study determined the effects of an aqueous extract Myrciaria jaboticaba peel (EJP) (50 g L-1) on 2,4,6-trinitrobenzenesulfonic acid-induced colitis. Wistar rats were randomized into five groups: HC-healthy control, CC-colitis DC-drug SJ-short-term treatment with EJP, and LJ-long-term EJP. The EJP treatments reduced body weight loss, stool consistency score, spleen enlargement. Gut...
Scientists have warned for several years that food systems become major drivers of environmental degradation, malnutrition, and insecurity. In this paper, we present arguments from specialists suggest that, in the transition to more sustainable systems, biodiversity security can be mutually supportive, rather than conflicting goals. We divided opinions these scientists into two "Big Topics". First, they examine synergies challenges intersection security. second section, explain how various...
Passion fruit (Passiflora edulis) is a native species from Brazil explored in culture. Peels are byproducts of juice industrial processing and usually discarded. They source fibers other bioactive substances, which may have antioxidant role to protect cells against oxidative stress. This study aimed evaluate the status P. edulis peel flour vivo. The male Wistar rats (77 days old) were divided Peel Control groups (n = 4). group was fed with standard diet (AIN-93M) group, received fifty...
Food biodiversity is vital for human health and sustainable food systems. However, research on neglected underutilized species limited by funding, uneven capacity, the challenge of balancing ecological, cultural, public considerations, requiring innovative prioritization approaches. Using Brazil as a model, this study inventories 369 across algae, aquatic fauna, wild terrestrial vertebrates, insects, mushrooms, plants. A mixed-methods approach, combining expert knowledge explainable AI...
In this study, we supplemented a high-fat diet (HF) with 5% powder of freeze-dried Syzygium malaccense fruit (HS) and investigated proofs peripheral insulin resistance, hippocampal AKT–GSK3-β–tau activation, learning/memory performance, brain frontal lobe oxidative stress. The intake HS did not prevent weight gain but promoted sensitivity, improved AKT signaling in the hippocampus, which prevented activation GSK3-β lowered tau phosphorylation induced HF. results from Morris water maze...
Previous studies have assessed the properties of aqueous extracts, using byproducts such as jaboticaba peel. We potential antioxidant effects extract (Plinia jaboticaba) (JAE = 50 g/L) in vitro and vivo. Healthy Wistar rats received ad libitum JAE for either 15 or 49 days Cyanidin-3-O-glucoside, delphinidin-3-O-glucoside, gallic acid, rutin, myricetin, quercetin were identified main polyphenols JAE. Lipid peroxidation values serum colon similar throughout groups. In addition, did not disturb...