The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, this is considered to be a marker of cardiovascular risk. Although many studies have demonstrated importance apoB/apoA-I in predicting presence or absence disease, less known about as plasma atherogenicity.A total 157 normolipidemic men aged 20-59 years were included study. levels cholesterol (TC), triglycerides (TG), high-density lipoprotein...

Objectives: It is known that professional occupation affects the heart rate variability (HRV).However, most studies have not taken into account seasonal features of HRV.The aim this study has been to evaluate HRV differences in winter and summer case Ministry Russian Federation for Civil Defense, Emergencies Elimination Consequences Natural Disasters (EMERCOM) workers scientific from Komi Science Center Ural Branch Academy Sciences.Material Methods: The short-term was examined 13 EMERCOM...

The ratio of low-density lipoprotein cholesterol to apolipoprotein-B (LDL-C/apoB) conventionally represents an alternative index LDL particle size.This study was undertaken determine the importance LDL-C/apoB in overall evaluation atherogenicity lipid profile.The plasma levels total (TC), triglycerides (TG), high-density (HDL-C), apolipoprotein (apo) A-I, apoB and apoE were measured 186 apparently healthy men using enzymatic immunoturbidimetric methods.The subjects with low values ratio,...

Background One of the topics discussed in sports science is use medium-chain saturated fat as an energy-saving nutrient additive when approaching high-intensity exercise. The purpose this study was to compare blood concentrations and long-chain fatty acids (FAs) across different intensity loads. Methods Fifteen male highly trained athletes from Russian cross-country skiing team participated study. Blood samples were drawn at rest, peak veloergometric test with a growing exercise load till...

The importance of blood lipids in the pathogenesis sudden sensorineural hearing loss (SSNHL) is widely discussed literature. However, published results that hyperlipidaemia causes problems are contradictory. objective this study was to establish whether increased lipid levels affect risk idiopathic SSNHL.A case-controlled conducted 27 patients with SSNHL and 24 healthy control subjects. All subjects underwent complete audiological examination. plasma total cholesterol (TC), triglycerides...

Background Among n-3 polyunsaturated fatty acids (PUFAs), the most important is α-linolenic acid (ALA). The biological activity of ALA not equivalent to that long-chain PUFAs, and it has pleiotropic effects, such as functioning an energy substrate during long-term training when carbohydrate reserves are depleted. purpose this investigation was study link between essential dietary plasma aerobic performance, which estimated via maximal fat oxidation (MFO), among skiers.Methods Twenty-four...

Apolipoprotein-E (apoE) is one of the metabolically active apoproteins and plays an important role in lipid metabolism. However, there are no data on levels apoE residents North spite fact that specific features metabolism northerners described. The present work was designed to study plasma European Russia.A total 937 native Russia (463 men 474 women) aged 13-60 years were included study. ApoE concentrations blood measured by immunoturbidimetric method.Plasma low. below defined normal values...

Hypertension and obesity often coexist. There are sex differences in the mechanisms of obesity-related hypertension but reasons for these still not fully understood.The aim this study was to investigate development associated with obesity.A total 866 men 1022 women were selected study. Anthropometric measurements, including arterial pressure performed. The plasma lipid levels measured using an enzymatic method commercially available kits.In both overweight obesity, hypertensive had more...

Abstract Among the many factors considered relevant to hypertension, obesity and metabolic disturbances play an important role in development of this pathology. Therefore, lipid accumulation product (LAP), index visceral adiposity, is a simple effective indicator hypertension risk. To date, reference cut-off values for LAP have not been defined. The aim study was determine age-adjusted optimal prediction This cross-sectional case–control comprised 1960 subjects ranging from 20 64 years age....

Background: The aim of this study was to investigate the relationships between levels n-3 essential polyunsaturated fatty acids (n-3 PUFAs) and stable nitric oxide (NO) metabolites in plasma athletes. Methods: Highly trained cross-country skiers (males, n = 39) were examined. acid profile total lipids determined by gas chromatography. NO level studied a colorimetric method via reaction with Griess reagent. Results: A widespread deficiency PUFAs athletes (more than 80% subjects) demonstrated...

Background: The Russian Arctic covers an enormous landmass with diverse environments. It inhabits more than 20 different ethnic groups, all of them various living conditions and food traditions. Indigenous populations a traditional way are exposed to large number anthropogenic pollutants, such as persistent organic pollutants (POPs) toxic metals, mainly through the diet. Human monitoring heavy metals in has only been performed on irregular intervals over past 15 years, thus, there is still...

Ожирение является важной медико-социальной проблемой, поскольку представляет серьезную угрозу для здоровья населения вследствие частого развития тяжелых сопутствующих заболеваний.Самым опасным видом ожирения считается висцеральное ожирение.Своевременная диагностика висцерального как на скрининговых осмотрах условно здорового населения, так и у лиц с сердечно-сосудистыми заболеваниями становится важным направлением первичной, вторичной профилактики.В обзоре рассматривается современный маркер...

Polyunsaturated fatty acid (PUFA) metabolites play important roles in the modulation of vascular tone, heart rate variability (HRV), and cardiovascular diseases. This study was undertaken to examine relationship between HRV plasma levels essential acids. Methods: Highly trained cross-country skiers participated (n = 19). Time-domain frequency-domain analyses were performed. The acids determined using gas–liquid chromatography. Results: Plasma eicosapentaenoic docosahexaenoic found be...

Background and Objectives: A sustained mismatch between energy intake (EI) exercise expenditure (EEE) can lead to Low Energy Availability (LEA), as well health performance impairments characteristic of Relative Deficiency in Sport (RED-S). Research females has identified specific LEA cut-points for the risks developing physiological disturbances. Cut-points males have yet be evaluated; therefore, this study examined prevalence highly trained male cross-country skiers. The key purpose was...

The objective of this study was to test the vectorelectrocardiographic T-wave characteristics for their associations with oxygen consumption (VO2) and physical performance during a maximal cardiopulmonary exercise (CPET) in highly trained cross-country skiers. Male skiers (n = 30) performed CPET on bicycle ergospirometric "Oxycon Pro" system simultaneous electrocardiogram recording. measurements were done at rest; stage preceding anaerobic threshold (preAnT); peak load; recovery. estimated...

The goal of this study was to examine the fatty acid (FA) composition total plasma lipids native inhabitants Russian European North, taking into consideration differences in lifestyles and nutritional habits as well interrelationship between FA profile nutrition.In total, 78 residents North (61 men 17 women) from two regions Komi Republic Northern Russia (Izhma settlement city Syktyvkar), aged 25-45 years, were included study. Izhma group consisted reindeer herders (17 women). comparison (44...

BACKGROUND: Obesity is a major health problem in modern society and its prevalence throughout the world has reached epidemic level. The unfavorable outcomes of obesity are associated with high risk numerous diseases due to metabolic disorders. Finding diagnostic criteria for early detection priority biomedical research. Therefore, particular interest new visceral marker lipid accumulation product (LAP). Meanwhile, date, reference values LAP not defined, data on sex- age-related changes...

The purpose of this study is to assess the production nitric oxide in professional cross-country skiers with normotensive and hypertensive responses physical activity at maximum load. observation group included (22.2 ± 7.1 years, = 107) who were current members national team Komi Republic. All examined athletes performed exercise test on a cycle ergometer “until exhaustion.” following parameters determined for each participant while they sitting rest, their anaerobic threshold level, during...

The purpose of our study was to identify the features metabolic regulation in highly trained cross-country skiers different qualifications at stages maximum load test. We examined 124 (male, ages 17-24). group consisted two subgroups based on their competition performance: 61 nonelite athletes (Group I) and 63 elite (group II), who were current members national team Komi Republic Russia. bicycle ergometer test performed by using OxyconPro system (Erich Jaeger, Hoechberg, Germany). All...

The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex ) from swimming. first group was randomly divided into six subgroups and subjected swimming test without load or 2%-10% body weight (BW). In group, we established that for rats, 4% BW optimal endurance assessment comparison other loads. second went through preliminary then two subgroups: long time (LST, Tex > 240 min) short (SST,...